Cell ID: CL0000037

Cell Name: hematopoietic stem cell

CSI Thresholds:

Select	Context	Threshold
	Overall	17.0939
	Dental pulp + Enamel caries	52.9596
	Enamel caries	52.9203
	Dental pulp + Healthy	26.4100
	Blood + Influenza	25.4265
	Blood + B-cell acute lymphoblastic leukemia	22.8912
	B-cell acute lymphoblastic leukemia	22.8554
	Dental pulp	22.4007
	Blood	21.7524
	Bone marrow + Healthy	19.1690
	Pulpitis	18.7792
	Dental pulp + Pulpitis	18.6304
	Healthy	17.1640
	Liver	14.6379
	Blood + COVID-19	14.3415
	Liver + Healthy	13.3849
	B-cell non-Hodgkin lymphoma	11.9951
	Bone marrow + B-cell non-Hodgkin lymphoma	11.9378
	Blood + Healthy	10.8020
	Influenza	9.3659
	Bone marrow	8.5914
	Lung	7.9164
	COVID-19	7.7721
	Spleen + Healthy	7.5561
	Spleen	7.5447
	Lymph node	7.5138
	Lung parenchyma	4.3970
	Lung parenchyma + Healthy	4.3898
	Yolk sac + Healthy	2.5374
	Yolk sac	2.4610
	Lymph node + Healthy	1.4314
	Skin of body	1.3312
	Skin of body + Healthy	1.3283
	Lung + Healthy	0.4008
	Inguinal lymph node	-1.4889
	Inguinal lymph node + Healthy	-1.6428
	Respiratory airway	-1.9206
	Respiratory airway + Healthy	-1.9581
	Thymus	-2.4711
	Thymus + Healthy	-2.4928

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(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119.

Synonyms: blood forming stem cell, hemopoietic stem cell, HSC, colony forming unit hematopoietic