Cell ID: CL0000134

Cell Name: mesenchymal stem cell

CSI Thresholds:

Select	Context	Threshold
	Overall	9.6744
	Pancreas + Healthy	2284.3075
	Pancreas	2225.3605
	Kidney + Wilms tumor	194.2242
	Wilms tumor	193.9567
	Muscle of abdomen	190.6387
	Muscle of abdomen + Healthy	190.6256
	Intestinal mucosa + Healthy	154.7444
	Intestinal mucosa	154.2059
	Rectus abdominis muscle	142.3375
	Rectus abdominis muscle + Healthy	142.3347
	Muscle of pelvic diaphragm	114.9149
	Muscle of pelvic diaphragm + Healthy	114.8967
	Vault of skull + Healthy	90.3229
	Vault of skull	90.3204
	Muscle tissue + Healthy	85.3956
	Muscle tissue	85.3873
	Adipose tissue	64.2709
	Adipose tissue + Healthy	64.2606
	Kidney + Healthy	64.1344
	Kidney	60.0116
	Uterus	53.4609
	Uterus + Healthy	52.2901
	Temporal lobe + Healthy	36.0839
	Gallbladder	34.0710
	Gallbladder + Healthy	33.4379
	Ovary + Healthy	23.7354
	Ovary	19.3246
	Adrenal gland	17.6116
	Skeletal muscle organ, vertebrate	14.1242
	Skeletal muscle organ, vertebrate + Healthy	14.0891
	Skin of body + Healthy	13.9644
	Skin of body	13.9616
	Rib + Healthy	13.7032
	Rib	13.6839
	Intestine	12.3513
	Lung + Healthy	10.6818
	Spinal cord + Healthy	9.9813
	Healthy	9.9060
	Spinal cord	9.7798
	Chorionic villus + Healthy	8.7430
	Chorionic villus	8.6340
	Omentum + Healthy	7.7584
	Stomach	7.4291
	Lung	7.2458
	Stomach + Healthy	7.1948
	Testis + Healthy	6.1999
	Testis	6.1611
	Eye + Healthy	5.7246
	Eye	5.6926
	Muscle organ + Healthy	5.2268
	Muscle organ	5.2225
	Heart + Healthy	4.9217
	Heart	4.9026
	Intestine + Healthy	4.4148
	Brain	4.3260
	Omentum	3.6009
	Brain + Healthy	2.2560
	Adrenal gland + Healthy	1.5120
	Placenta + Healthy	0.3186
	Bone marrow + Down syndrome	-3.0961
	Bone marrow	-3.1162
	Down syndrome	-3.1393
	Ileum	-4.8237
	Temporal lobe	-6.1567
	Subcutaneous adipose tissue	-7.3809
	Subcutaneous adipose tissue + Healthy	-7.5768
	Esophagus	-8.1590
	Esophagus + Healthy	-8.6854
	Placenta	-8.8569
	Ileum + Healthy	-43.1976
	Transverse colon + Healthy	-50.0101
	Transverse colon	-73.2770
	Ascending colon + Healthy	-198.1509
	Ascending colon	-303.3086

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs.

Synonyms: bone marrow stromal cells, colony-forming unit-fibroblast, marrow stromal cells, BMSC, CFU-F, MSC, mesenchymal precursor cell, mesenchymal progenitor cells, mesenchymal stem cell, mesenchymal stromal cell, mesenchymal stromal cells, stem cells, mesenchymal