Cell ID: CL0000155

Cell Name: peptic cell

CSI Thresholds:

Select	Context	Threshold
	Overall	8.8875
	Barrett esophagus	306.3961
	Lower esophagus + Barrett esophagus	302.0298
	Lower esophagus + Healthy	285.6772
	Esophagogastric junction + Healthy	124.0637
	Esophagogastric junction	118.5866
	Lower esophagus	100.2275
	Cardia of stomach	96.3963
	Gastric intestinal metaplasia	96.3340
	MONDO0004298	96.1816
	Cardia of stomach + Gastric intestinal metaplasia	94.5403
	Body of stomach	83.8218
	Body of stomach + Gastric intestinal metaplasia	83.4689
	Body of stomach	74.1726
	Cardia of stomach	73.3571
	Cardia of stomach + Healthy	64.2643
	Body of stomach + Gastritis	60.1050
	Gastritis	59.9672
	Stomach	18.1032
	Stomach + Healthy	17.9168
	Healthy	9.1843
	Duodenum	7.9696
	Duodenum + Healthy	7.9331
	Body of stomach + Healthy	7.7903

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: An epithelial cell of the stomach that is part of the fundic gastric gland. This cell is characterized by a basally located nucleus, abundant rough endoplasmic reticulum, and large apical secretory granules. It produces and secretes pepsinogen, the inactive precursor of the digestive enzyme pepsin.

Synonyms: chief cell of stomach, gastric chief cell, pepsinogen secreting cell, zymogenic cell