Cell ID: CL0000162

Cell Name: parietal cell

CSI Thresholds:

Select	Context	Threshold
	Overall	9.4597
	Lower esophagus + Barrett esophagus	441.8852
	Barrett esophagus	439.9282
	Lower esophagus + Healthy	292.5672
	Lower esophagus	227.7719
	Body of stomach + Gastric intestinal metaplasia	149.5311
	Body of stomach	148.7235
	Esophagogastric junction + Healthy	135.8689
	Esophagogastric junction	134.3801
	Cardia of stomach + Gastric intestinal metaplasia	131.7613
	Cardia of stomach	131.2198
	MONDO0004298	121.3496
	Gastric intestinal metaplasia	121.1781
	Cardia of stomach	117.1432
	Body of stomach	92.7511
	Cardia of stomach + Healthy	67.6448
	Body of stomach + Gastritis	54.5188
	Gastritis	53.9044
	Body of stomach + Healthy	9.8931
	Healthy	8.8092
	Duodenum + Healthy	-0.0440
	Duodenum	-1.0880

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: An epithelial cell of the stomach that is part of the fundic gastric gland. This cell is characterized by its pyramidal shape, abundant mitochondria, and a complex network of secretory canaliculi lined with microvilli. It secretes hydrochloric acid into the stomach lumen and produces intrinsic factor, essential for vitamin B12 absorption.

Synonyms: gastric parietal cell, oxyntic cell