Cell ID: CL0000442

Cell Name: follicular dendritic cell

CSI Thresholds:

Select	Context	Threshold
	Overall	6.0045
	Tonsil + Healthy	33.8798
	Tonsil	33.7197
	Lymph node + Follicular lymphoma	30.8719
	Follicular lymphoma	30.4296
	Nasal cavity + Healthy	12.3654
	Nasal cavity + COVID-19	11.4047
	Small intestine	7.3905
	Lymph node	7.3609
	Nasal cavity	7.1010
	Small intestine + Healthy	3.1667
	Healthy	2.6290
	Lymph node + Healthy	2.1675
	COVID-19	2.1354

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the dendritic cell associated with T cells. Follicular dendritic cells have Fc receptors and C3b receptors, but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response.