Cell ID: CL0000492

Cell Name: CD4-positive helper T cell

CSI Thresholds:

Select	Context	Threshold
	Overall	10.1023
	Esophagogastric junction + Healthy	762.1690
	Esophagogastric junction	760.4560
	Lower esophagus + Healthy	612.5230
	Barrett esophagus	406.9179
	Lower esophagus + Barrett esophagus	405.5475
	Cardia of stomach + Gastric intestinal metaplasia	232.1981
	Cardia of stomach	230.6595
	Cardia of stomach	154.6929
	Body of stomach	150.2694
	Body of stomach + Gastric intestinal metaplasia	150.1186
	Lower esophagus	149.4565
	MONDO0004298	144.7946
	Gastric intestinal metaplasia	144.6878
	Body of stomach + Gastritis	116.1955
	Gastritis	115.9376
	Blood + Post-COVID-19 disorder	109.1410
	Post-COVID-19 disorder	108.8728
	Cardia of stomach + Healthy	102.7638
	Submucosal esophageal gland	96.4657
	Submucosal esophageal gland + Healthy	95.2606
	Body of stomach	84.3752
	Lamina propria + Healthy	71.4631
	Lamina propria	71.2171
	Omentum	59.1486
	Caecum + Healthy	57.0242
	Omentum + Healthy	38.2514
	Ileum	34.9042
	Thymus + Healthy	34.6855
	Thymus	34.6755
	Transverse colon	34.0473
	Tonsil	33.4291
	Tonsil + Healthy	33.2632
	Duodenum + Healthy	32.9700
	Duodenum	32.8600
	Ileum + Healthy	28.8365
	Kidney	27.5913
	Liver	25.0736
	Kidney + Healthy	23.3461
	Bone marrow + Healthy	21.8275
	Parotid gland + Healthy	21.3348
	Parotid gland	21.2509
	Breast + Healthy	20.0199
	Thoracic lymph node + Healthy	19.6317
	Sigmoid colon	19.5833
	Thoracic lymph node	19.5531
	Breast	17.6767
	Blood	15.8838
	Blood + COVID-19	13.5440
	Mesenteric lymph node + Healthy	13.0441
	Mesenteric lymph node	12.9972
	Renal cell carcinoma	12.3542
	Skeletal muscle tissue + Healthy	11.4886
	Skeletal muscle tissue	11.4077
	Influenza	10.9377
	Caecum	10.7640
	Lymph node	10.3208
	Jejunal epithelium	9.6630
	Jejunal epithelium + Healthy	9.6459
	Lung + Renal cell carcinoma	9.1227
	Bone marrow	8.8988
	Lymph node + Metastatic melanoma	8.8961
	Metastatic melanoma	8.8956
	Healthy	8.8596
	Liver + Healthy	8.6749
	Spleen + Healthy	8.2286
	Spleen	8.2277
	Lung + Healthy	8.1958
	Sigmoid colon + Healthy	7.9411
	Lung	5.4342
	Body of stomach + Healthy	5.3408
	Transverse colon + Healthy	4.5927
	Blood + Influenza	4.4798
	COVID-19	4.2946
	Blood + Healthy	3.8501
	Skin of body + Healthy	2.8685
	Skin of body	2.8355
	Lymph node + Healthy	1.9101
	Kidney + Renal cell carcinoma	0.0290
	Skin of chest	-6.3458
	Skin of chest + Healthy	-6.4022
	Skin of abdomen	-9.8279
	Skin of abdomen + Healthy	-9.8323

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A CD4-positive, alpha-beta T cell that cooperates with other lymphocytes via direct contact or cytokine release to initiate a variety of immune functions.

Synonyms: CD4-positive T-helper cell, CD4-positive helper T lymphocyte, CD4-positive helper T-cell, CD4-positive helper T-lymphocyte