Cell ID: CL0000502

Cell Name: type D enteroendocrine cell

CSI Thresholds:

Select	Context	Threshold
	Overall	4.1566
	Ileum	15.6556
	Small intestine	6.7095
	Small intestine + Healthy	3.8770
	Large intestine	3.0023
	Large intestine + Healthy	1.9606
	Healthy	1.8202
	Ileum + Healthy	-4.0822
	Jejunum	-96.1270
	Jejunum + Healthy	-96.3366

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin.

Synonyms: D cell