Cell ID: CL0000556

Cell Name: megakaryocyte

CSI Thresholds:

Select	Context	Threshold
	Overall	16.1962
	Forelimb	30.3198
	Lung + COVID-19	30.2276
	Forelimb + Healthy	30.1412
	Placenta	25.3468
	Liver	24.5673
	Telencephalon + Healthy	23.2417
	Liver + Healthy	22.8756
	Small intestine	22.8251
	Placenta + Healthy	22.1407
	Colorectum	21.0506
	B-cell non-Hodgkin lymphoma	20.5893
	Bone marrow + B-cell non-Hodgkin lymphoma	20.5225
	Hindlimb + Healthy	20.4197
	Hindlimb	20.2477
	Skeletal muscle tissue	20.0779
	Skeletal muscle tissue + Healthy	20.0237
	Uvea	19.5950
	Uvea + Uveal melanoma	19.3368
	Blood + Clear cell renal carcinoma	19.1090
	Uveal melanoma	19.0125
	Gonad + Healthy	18.7464
	Gonad	18.6725
	Ileum	18.4690
	Blood	17.9973
	Jejunal epithelium + Healthy	16.7019
	Jejunal epithelium	15.9411
	Healthy	15.5413
	Breast	15.2473
	Kidney + Clear cell renal carcinoma	13.8495
	Blood + COVID-19	13.3285
	Bone marrow + Healthy	12.2669
	Lung + Lung cancer	11.9505
	Blood + Healthy	11.7682
	Lung cancer	11.6795
	Ovary	11.4459
	Ovarian cancer	11.3357
	Ovary + Ovarian cancer	11.3303
	Kidney	10.9806
	Clear cell renal carcinoma	9.3241
	Telencephalon	9.3165
	Lower lobe of left lung	9.1177
	Lower lobe of left lung + Healthy	9.0873
	Spleen	8.8749
	Spleen + Healthy	8.8689
	Breast cancer	8.6828
	Lung	7.7096
	COVID-19	7.2852
	Bone marrow	6.2238
	Adrenal gland	4.1988
	Kidney + Healthy	4.1383
	Heart	3.4019
	Heart + Healthy	3.3483
	Thymus + Healthy	3.2426
	Thymus	3.2210
	Large intestine	3.0916
	Lung + Healthy	2.8902
	Colorectum + Colorectal cancer	2.6714
	Colorectal cancer	2.6593
	Large intestine + Healthy	2.6080
	Adrenal gland + Healthy	2.5249
	Skin of body + Healthy	2.3010
	Skin of body	2.2741
	Yolk sac + Healthy	1.9665
	Yolk sac	1.9661
	Upper lobe of left lung + Healthy	1.8861
	Upper lobe of left lung	1.6581
	Small intestine + Healthy	0.2811
	Colorectum + Healthy	0.1456
	Muscle organ	-0.1127
	Muscle organ + Healthy	-0.1182
	Breast + Breast cancer	-0.4107
	Down syndrome	-0.5181
	Bone marrow + Down syndrome	-0.5191
	Ileum + Healthy	-2.2596

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release.

Synonyms: megacaryocyte, megalocaryocyte, megalokaryocyte