Cell ID: CL0000794

Cell Name: CD8-positive, alpha-beta cytotoxic T cell

CSI Thresholds:

Select	Context	Threshold
	Overall	8.0975
	Lung parenchyma + Healthy	173.9132
	Lung parenchyma	173.3311
	Nasopharynx + Healthy	77.2802
	Blood + Post-COVID-19 disorder	76.9341
	Post-COVID-19 disorder	74.6529
	Labial gland + Healthy	46.9566
	Tonsil + Healthy	46.6426
	Tonsil	46.4800
	Blood + Healthy	37.9363
	Sjogren syndrome	35.5937
	Labial gland + Sjogren syndrome	35.4530
	Labial gland	29.1904
	Heart left ventricle + Healthy	26.2850
	Interventricular septum	24.8329
	Blood + B-cell acute lymphoblastic leukemia	23.0108
	B-cell acute lymphoblastic leukemia	23.0006
	Interventricular septum + Healthy	21.9917
	Apex of heart	17.2189
	Apex of heart + Healthy	16.9934
	Heart left ventricle	16.0589
	Nasopharynx	15.1781
	Heart right ventricle	14.9493
	Blood + COVID-19	12.6806
	Heart right ventricle + Healthy	10.4477
	Blood	9.0500
	Healthy	8.6410
	COVID-19	7.5793
	Nasopharynx + COVID-19	7.3783
	Lung	6.7898
	Skin of body	5.9742
	Skin of body + Healthy	5.9673
	Left cardiac atrium + Healthy	5.6334
	Left cardiac atrium	5.6045
	Thymus + Healthy	4.6889
	Thymus	4.6841
	Right cardiac atrium + Healthy	3.4058
	Right cardiac atrium	3.3757
	Lung + Healthy	2.9825
	Respiratory failure	2.3586
	Nasopharynx + Respiratory failure	2.3562
	Nasopharynx + Long COVID-19	2.2330
	Long COVID-19	2.2132
	Epithelium of esophagus + Healthy	1.5857
	Epithelium of esophagus	1.5856
	Skin of abdomen	0.1146
	Skin of abdomen + Healthy	0.1121
	Skin of chest	-0.3295
	Skin of chest + Healthy	-0.3321

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive.

Synonyms: cytotoxic T cell, cytotoxic T lymphocyte, cytotoxic T-cell, cytotoxic T-lymphocyte, killer T cell, killer T lymphocyte, killer T-cell, killer T-lymphocyte, CD8-positive, alpha-beta cytotoxic T lymphocyte, CD8-positive, alpha-beta cytotoxic T-cell, CD8-positive, alpha-beta cytotoxic T-lymphocyte