Cell ID: CL0000826

Cell Name: pro-B cell

CSI Thresholds:

Select	Context	Threshold
	Overall	10.7525
	Blood + B-cell acute lymphoblastic leukemia	43.9259
	B-cell acute lymphoblastic leukemia	43.9202
	Blood	34.2855
	Thoracic lymph node + Healthy	34.1610
	Thoracic lymph node	33.9209
	Gonad	30.2143
	Gonad + Healthy	30.2027
	Ileum	17.4484
	Mesenteric lymph node	15.2991
	Mesenteric lymph node + Healthy	15.2289
	Lymph node	12.4569
	Kidney	12.3923
	Bone marrow + Healthy	10.5093
	Healthy	10.3924
	Large intestine	9.7267
	Bone marrow	8.5961
	Lymph node + Healthy	8.5085
	Spleen	8.2516
	Spleen + Healthy	8.1899
	Lung	8.1561
	Liver	8.0304
	Liver + Healthy	7.8559
	Small intestine	7.7677
	Small intestine + Healthy	4.1888
	Large intestine + Healthy	3.7399
	Skin of body	2.7637
	Skin of body + Healthy	2.7473
	Lung + Healthy	1.6502
	Kidney + Healthy	0.4381
	Ileum + Healthy	-6.9510
	Umbilical cord blood	-6.9824
	Umbilical cord blood + Healthy	-6.9959

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs.

Synonyms: pre-pro B cell, pro-B lymphocyte, pro-B-cell, pro-B-lymphocyte, progenitor B cell, progenitor B lymphocyte, progenitor B-cell, progenitor B-lymphocyte, pre-B cell (Philadelphia nomenclature)