Cell ID: CL0000844

Cell Name: germinal center B cell

CSI Thresholds:

Select	Context	Threshold
	Overall	7.0665
	Transverse colon	77.7681
	Transverse colon + Healthy	47.0406
	Sigmoid colon + Healthy	43.7135
	Ileum + Healthy	41.6860
	Bone marrow + Healthy	29.4778
	Ileum	28.7878
	Thoracic lymph node + Healthy	27.2344
	Thoracic lymph node	27.2011
	Jejunal epithelium	26.5296
	Jejunal epithelium + Healthy	26.5258
	Sigmoid colon	21.5871
	Lamina propria of small intestine	19.9269
	Lamina propria of small intestine + Digestive system disorder	19.8518
	Digestive system disorder	19.7162
	Caecum + Healthy	15.9707
	Mesenteric lymph node	15.9306
	Mesenteric lymph node + Healthy	15.8895
	Liver + Healthy	13.6991
	Caecum	11.2165
	Bone marrow	10.7746
	Liver	10.7240
	Spleen	9.6874
	Spleen + Healthy	9.6751
	Lung	9.6145
	Duodenum + Healthy	9.3653
	Duodenum	9.3520
	Healthy	5.4549
	Small intestine	5.2732
	Thymus	4.0726
	Thymus + Healthy	3.9829
	Lung + Healthy	3.2122
	Small intestine + Healthy	1.9594

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A rapidly cycling mature B cell that has distinct phenotypic characteristics and is involved in T-dependent immune responses and located typically in the germinal centers of lymph nodes. This cell type expresses Ly77 after activation.

Synonyms: GC B cell, GC B lymphocyte, GC B-cell, GC B-lymphocyte, germinal center B lymphocyte, germinal center B-cell, germinal center B-lymphocyte