Cell ID: CL0000863

Cell Name: inflammatory macrophage

CSI Thresholds:

Select	Context	Threshold
	Overall	7.6837
	Nasopharynx + Healthy	106.0622
	Caudate lobe of liver + Healthy	100.5799
	Labial gland + Healthy	51.4649
	Dermis + Healthy	49.3764
	Labial gland + Sjogren syndrome	48.8415
	Sjogren syndrome	48.6828
	Dermis	48.5632
	Caudate lobe of liver	37.3362
	Labial gland	28.8431
	Nasopharynx	24.8877
	Skin epidermis	20.9464
	Skin epidermis + Healthy	20.8245
	Ileum	17.3673
	Mesenteric lymph node	16.7558
	Liver + Healthy	16.7080
	Mesenteric lymph node + Healthy	16.6913
	Breast	15.6182
	Liver	14.7688
	Lymph node	12.6076
	COVID-19	10.9975
	Lymph node + Healthy	9.1335
	Small intestine	7.8777
	Nasopharynx + COVID-19	7.4757
	Breast + Healthy	6.5614
	Healthy	5.8001
	Small intestine + Healthy	2.2669
	Respiratory failure	1.6387
	Nasopharynx + Respiratory failure	1.6348
	Large intestine + Healthy	-0.0109
	Large intestine	-1.3058
	Ileum + Healthy	-3.2705

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: An elicited macrophage that is recruited into the tissues in response to injury and infection as part of an inflammatory response, expresses high levels of pro-inflammatory cytokines, ROS and NO, and shows potent microbicidal activity.

Synonyms: classically activated macrophage, M1 macrophage