Cell ID: CL0000895

Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell

CSI Thresholds:

Select	Context	Threshold
	Overall	8.6289
	Post-COVID-19 disorder	192.6146
	Blood + Post-COVID-19 disorder	192.4113
	Mesenteric lymph node + Healthy	67.9991
	Mesenteric lymph node	67.9939
	Ileum + Healthy	61.0923
	Thoracic lymph node	57.4185
	Thoracic lymph node + Healthy	57.3973
	Follicular lymphoma	56.3548
	Lymph node + Follicular lymphoma	56.1361
	Blood + Juvenile dermatomyositis	45.8741
	Juvenile dermatomyositis	45.8656
	Ileum	40.1581
	Omentum	28.4186
	HIV infectious disease	28.1749
	Blood + HIV infectious disease	28.0817
	Breast + Healthy	26.1700
	Respiratory system disorder	24.0488
	Blood + Respiratory system disorder	24.0469
	Jejunal epithelium	22.4218
	Jejunal epithelium + Healthy	22.3620
	Breast	19.0560
	Bone marrow + Healthy	14.4829
	COVID-19	14.2326
	Lamina propria + Healthy	13.1226
	Lamina propria	12.9948
	Blood + Healthy	12.0479
	Skeletal muscle tissue	11.8030
	Skeletal muscle tissue + Healthy	11.7824
	Blood + COVID-19	11.6587
	Blood + B-cell acute lymphoblastic leukemia	11.3234
	B-cell acute lymphoblastic leukemia	11.3130
	Blood + Common variable immunodeficiency	9.8779
	Common variable immunodeficiency	9.8731
	Kidney	9.6976
	Healthy	9.6076
	Liver + Healthy	8.5487
	Lymph node	8.4508
	Liver	8.4503
	Adrenal tissue	8.2104
	Lung	7.2974
	Omentum + Healthy	7.0484
	Blood	6.8849
	Nonpapillary renal cell carcinoma	6.2335
	Spleen	6.1801
	Spleen + Healthy	6.1565
	Bone marrow	3.9211
	Skin of body	3.8672
	Adrenal tissue + Healthy	3.8592
	Skin of body + Healthy	3.8341
	Kidney + Nonpapillary renal cell carcinoma	3.8162
	Lymph node + Healthy	3.8065
	Kidney + Kidney oncocytoma	3.7608
	Kidney oncocytoma	3.7419
	Perirenal fat + Healthy	3.6006
	Perirenal fat	3.5862
	Trachea + Healthy	3.5571
	Lower lobe of left lung + Healthy	3.5565
	Lower lobe of left lung	3.5497
	Blood + Rheumatoid arthritis	3.4193
	Rheumatoid arthritis	3.3865
	Thymus	3.1065
	Thymus + Healthy	3.0451
	Vein	3.0305
	Vein + Nonpapillary renal cell carcinoma	3.0250
	Trachea	3.0218
	Lung + Healthy	2.9550
	Caecum + Healthy	2.9526
	Caecum	2.9338
	Upper lobe of left lung + Healthy	1.9463
	Upper lobe of left lung	1.9431
	Bronchus + Healthy	1.8465
	Bronchus	1.8403
	Adrenal tissue + Nonpapillary renal cell carcinoma	0.6927
	Kidney + Healthy	0.6358
	Skin of chest	0.3829
	Skin of chest + Healthy	0.3786
	Skin of abdomen + Healthy	0.1068
	Skin of abdomen	0.0871
	Yolk sac	-0.2621
	Yolk sac + Healthy	-0.2639

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(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: An antigen inexperienced CD4-positive, alpha-beta T cell with the phenotype CCR7-positive, CD127-positive and CD62L-positive. This cell type develops in the thymus. This cell type is also described as being CD25-negative, CD62L-high, and CD44-low.

Synonyms: naive CD4+ T cell, T.4Nve.Sp, Th0, naive thymus-derived CD4-positive, alpha-beta T lymphocyte, naive thymus-derived CD4-positive, alpha-beta T-cell, naive thymus-derived CD4-positive, alpha-beta T-lymphocyte