Cell ID: CL0000938

Cell Name: CD16-negative, CD56-bright natural killer cell, human

CSI Thresholds:

Select	Context	Threshold
	Overall	10.3626
	Ileum + Healthy	74.6845
	Decidua	70.1158
	Decidua + Healthy	70.0477
	Transverse colon	66.6716
	Liver	54.8750
	Ileum	52.2387
	Nasal cavity + COVID-19	33.4313
	Omentum	32.7706
	Skeletal muscle tissue + Healthy	29.9531
	Skeletal muscle tissue	29.9330
	Nasal cavity + Healthy	24.9797
	Blood + Juvenile dermatomyositis	22.3447
	Juvenile dermatomyositis	22.2724
	Respiratory system disorder	20.3979
	Blood + Respiratory system disorder	20.3786
	Blood	20.0090
	Liver + Healthy	17.5421
	Blood + Post-COVID-19 disorder	16.0965
	Post-COVID-19 disorder	16.0067
	Bronchus + Healthy	13.5275
	Nasal cavity	13.0978
	Blood + COVID-19	12.5146
	Bone marrow + Healthy	11.7845
	Omentum + Healthy	11.5978
	Blood + HIV infectious disease	10.8707
	HIV infectious disease	10.8575
	Duodenum	10.7196
	Duodenum + Healthy	10.5614
	Intercostal muscle + Healthy	9.5518
	Healthy	9.5460
	Intercostal muscle	9.4913
	Common variable immunodeficiency	8.6492
	Blood + Common variable immunodeficiency	8.6381
	Blood + Healthy	7.8205
	Bronchus + COVID-19	7.1009
	COVID-19	6.9739
	Lung	6.8056
	Transverse colon + Healthy	6.5293
	Bone marrow	6.5288
	Thoracic lymph node + Healthy	6.3430
	Thoracic lymph node	6.2935
	Trachea + COVID-19	5.5176
	Bronchus	5.2195
	Mesenteric lymph node + Healthy	4.0319
	Mesenteric lymph node	4.0157
	Lung + Healthy	3.4113
	Spleen	3.3454
	Spleen + Healthy	3.3441
	Caecum + Healthy	1.9396
	Caecum	1.9282
	Trachea	1.4988
	Trachea + Healthy	1.0033
	Lamina propria	0.6321
	Lamina propria + Healthy	0.6280
	Jejunal epithelium	0.3859
	Jejunal epithelium + Healthy	0.3837
	Down syndrome	-4.2232
	Bone marrow + Down syndrome	-4.2507

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: NK cell that has the phenotype CD56-bright, CD16-negative, and CD84-positive with the function to secrete interferon-gamma but is not cytotoxic.

Synonyms: CD16-CD56bright NK cell, CD16-negative, CD56-bright NK cell, CD56-bright cytokine secreting NK cell, CD56-bright cytokine secreting natural killer cell