Cell ID: CL0000956

Cell Name: pre-B-I cell

CSI Thresholds:

Select	Context	Threshold
	Overall	4.6975
	Lung	7.8510
	Lung + Healthy	4.1242
	Healthy	2.0224

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein.

Synonyms: pre-BI cell, pro-B cell (Philadelphia nomenclature)