Details for: CL0001063

Cell ID: CL0001063

Cell Name: neoplastic cell

Marker Score Threshold: 6,062
(Derived using integrated single-cell and genomic data)

Description: An abnormal cell exhibiting dysregulation of cell proliferation or programmed cell death and capable of forming a neoplasm, an aggregate of cells in the form of a tumor mass or an excess number of abnormal cells (liquid tumor) within an organism.

Synonyms: tumor cell, tumour cell

Genes (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Gene Symbol: FBXO31 (ENSG00000103264)
    Fold Change: 4.4
    Ensembl ID: ENSG00000103264
  • Gene Symbol: TTN (ENSG00000155657)
    Fold Change: 1.94
    Ensembl ID: ENSG00000155657
  • Gene Symbol: PTPRS (ENSG00000105426)
    Fold Change: 1.31
    Ensembl ID: ENSG00000105426
  • Gene Symbol: TAS2R13 (ENSG00000212128)
    Fold Change: 1.25
    Ensembl ID: ENSG00000212128
  • Gene Symbol: OR4D2 (ENSG00000255713)
    Fold Change: 1.25
    Ensembl ID: ENSG00000255713
  • Gene Symbol: TP53TG3 (ENSG00000183632)
    Fold Change: 1.25
    Ensembl ID: ENSG00000183632
  • Gene Symbol: TAS2R9 (ENSG00000121381)
    Fold Change: 1.25
    Ensembl ID: ENSG00000121381
  • Gene Symbol: TAS2R43 (ENSG00000255374)
    Fold Change: 1.25
    Ensembl ID: ENSG00000255374
  • Gene Symbol: DEFA4 (ENSG00000164821)
    Fold Change: 1.25
    Ensembl ID: ENSG00000164821
  • Gene Symbol: IFNA5 (ENSG00000147873)
    Fold Change: 1.25
    Ensembl ID: ENSG00000147873
  • Gene Symbol: RNY3 (ENSG00000202354)
    Fold Change: 1.25
    Ensembl ID: ENSG00000202354
  • Gene Symbol: GPR52 (ENSG00000203737)
    Fold Change: 1.25
    Ensembl ID: ENSG00000203737
  • Gene Symbol: OR10A3 (ENSG00000170683)
    Fold Change: 1.25
    Ensembl ID: ENSG00000170683
  • Gene Symbol: PRLH (ENSG00000071677)
    Fold Change: 1.25
    Ensembl ID: ENSG00000071677
  • Gene Symbol: OR6N2 (ENSG00000188340)
    Fold Change: 1.25
    Ensembl ID: ENSG00000188340
  • Gene Symbol: SPATA8 (ENSG00000185594)
    Fold Change: 1.25
    Ensembl ID: ENSG00000185594
  • Gene Symbol: TAS2R19 (ENSG00000212124)
    Fold Change: 1.25
    Ensembl ID: ENSG00000212124
  • Gene Symbol: GJA8 (ENSG00000121634)
    Fold Change: 1.25
    Ensembl ID: ENSG00000121634
  • Gene Symbol: IFNB1 (ENSG00000171855)
    Fold Change: 1.25
    Ensembl ID: ENSG00000171855
  • Gene Symbol: TRGV1 (ENSG00000211701)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211701
  • Gene Symbol: TRBV16 (ENSG00000275243)
    Fold Change: 1.25
    Ensembl ID: ENSG00000275243
  • Gene Symbol: OR6P1 (ENSG00000186440)
    Fold Change: 1.25
    Ensembl ID: ENSG00000186440
  • Gene Symbol: CCT8L2 (ENSG00000198445)
    Fold Change: 1.25
    Ensembl ID: ENSG00000198445
  • Gene Symbol: CBLL2 (ENSG00000175809)
    Fold Change: 1.25
    Ensembl ID: ENSG00000175809
  • Gene Symbol: OR5B21 (ENSG00000198283)
    Fold Change: 1.25
    Ensembl ID: ENSG00000198283
  • Gene Symbol: INSL4 (ENSG00000120211)
    Fold Change: 1.25
    Ensembl ID: ENSG00000120211
  • Gene Symbol: ZRSR2P1 (ENSG00000212643)
    Fold Change: 1.25
    Ensembl ID: ENSG00000212643
  • Gene Symbol: XAGE2 (ENSG00000155622)
    Fold Change: 1.25
    Ensembl ID: ENSG00000155622
  • Gene Symbol: TRAJ5 (ENSG00000211884)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211884
  • Gene Symbol: RIMBP3 (ENSG00000275793)
    Fold Change: 1.25
    Ensembl ID: ENSG00000275793
  • Gene Symbol: TPD52L3 (ENSG00000170777)
    Fold Change: 1.25
    Ensembl ID: ENSG00000170777
  • Gene Symbol: KIR3DL3 (ENSG00000242019)
    Fold Change: 1.25
    Ensembl ID: ENSG00000242019
  • Gene Symbol: PSMB11 (ENSG00000222028)
    Fold Change: 1.25
    Ensembl ID: ENSG00000222028
  • Gene Symbol: TAS2R41 (ENSG00000221855)
    Fold Change: 1.25
    Ensembl ID: ENSG00000221855
  • Gene Symbol: TAS2R20 (ENSG00000255837)
    Fold Change: 1.25
    Ensembl ID: ENSG00000255837
  • Gene Symbol: SEMG2 (ENSG00000124157)
    Fold Change: 1.25
    Ensembl ID: ENSG00000124157
  • Gene Symbol: SPRR2G (ENSG00000159516)
    Fold Change: 1.25
    Ensembl ID: ENSG00000159516
  • Gene Symbol: RNU6 1 (ENSG00000206625)
    Fold Change: 1.25
    Ensembl ID: ENSG00000206625
  • Gene Symbol: BMP10 (ENSG00000163217)
    Fold Change: 1.25
    Ensembl ID: ENSG00000163217
  • Gene Symbol: OR52N1 (ENSG00000181001)
    Fold Change: 1.25
    Ensembl ID: ENSG00000181001
  • Gene Symbol: TSSK1B (ENSG00000212122)
    Fold Change: 1.25
    Ensembl ID: ENSG00000212122
  • Gene Symbol: TXNDC2 (ENSG00000168454)
    Fold Change: 1.25
    Ensembl ID: ENSG00000168454
  • Gene Symbol: DNAJB8 (ENSG00000179407)
    Fold Change: 1.25
    Ensembl ID: ENSG00000179407
  • Gene Symbol: SPZ1 (ENSG00000164299)
    Fold Change: 1.25
    Ensembl ID: ENSG00000164299
  • Gene Symbol: IL3 (ENSG00000164399)
    Fold Change: 1.25
    Ensembl ID: ENSG00000164399
  • Gene Symbol: SNORA73B (ENSG00000200087)
    Fold Change: 1.25
    Ensembl ID: ENSG00000200087
  • Gene Symbol: IGHV4 28 (ENSG00000211952)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211952
  • Gene Symbol: IGHV1 69 2 (ENSG00000281990)
    Fold Change: 1.25
    Ensembl ID: ENSG00000281990
  • Gene Symbol: FTMT (ENSG00000181867)
    Fold Change: 1.25
    Ensembl ID: ENSG00000181867
  • Gene Symbol: PTH2 (ENSG00000142538)
    Fold Change: 1.25
    Ensembl ID: ENSG00000142538
  • Gene Symbol: OR52K2 (ENSG00000181963)
    Fold Change: 1.25
    Ensembl ID: ENSG00000181963
  • Gene Symbol: ANKRD60 (ENSG00000124227)
    Fold Change: 1.25
    Ensembl ID: ENSG00000124227
  • Gene Symbol: KHDC3L (ENSG00000203908)
    Fold Change: 1.25
    Ensembl ID: ENSG00000203908
  • Gene Symbol: DAOA (ENSG00000182346)
    Fold Change: 1.25
    Ensembl ID: ENSG00000182346
  • Gene Symbol: NPBWR2 (ENSG00000125522)
    Fold Change: 1.25
    Ensembl ID: ENSG00000125522
  • Gene Symbol: PRL (ENSG00000172179)
    Fold Change: 1.25
    Ensembl ID: ENSG00000172179
  • Gene Symbol: SNORD13P3 (ENSG00000239128)
    Fold Change: 1.25
    Ensembl ID: ENSG00000239128
  • Gene Symbol: TRBV6 7 (ENSG00000253188)
    Fold Change: 1.25
    Ensembl ID: ENSG00000253188
  • Gene Symbol: TRBJ2 2 (ENSG00000211765)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211765
  • Gene Symbol: CTAG2 (ENSG00000126890)
    Fold Change: 1.25
    Ensembl ID: ENSG00000126890
  • Gene Symbol: OR2B2 (ENSG00000168131)
    Fold Change: 1.25
    Ensembl ID: ENSG00000168131
  • Gene Symbol: PRPS1L1 (ENSG00000229937)
    Fold Change: 1.25
    Ensembl ID: ENSG00000229937
  • Gene Symbol: CHRM4 (ENSG00000180720)
    Fold Change: 1.25
    Ensembl ID: ENSG00000180720
  • Gene Symbol: RNY1 (ENSG00000201098)
    Fold Change: 1.25
    Ensembl ID: ENSG00000201098
  • Gene Symbol: SPRR2F (ENSG00000244094)
    Fold Change: 1.25
    Ensembl ID: ENSG00000244094
  • Gene Symbol: IGHV3 73 (ENSG00000211976)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211976
  • Gene Symbol: IGHV3 64 (ENSG00000223648)
    Fold Change: 1.25
    Ensembl ID: ENSG00000223648
  • Gene Symbol: IGHV3 35 (ENSG00000211957)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211957
  • Gene Symbol: IGHV3 20 (ENSG00000211946)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211946
  • Gene Symbol: OR1Q1 (ENSG00000165202)
    Fold Change: 1.25
    Ensembl ID: ENSG00000165202
  • Gene Symbol: OR1E1 (ENSG00000180016)
    Fold Change: 1.25
    Ensembl ID: ENSG00000180016
  • Gene Symbol: MC4R (ENSG00000166603)
    Fold Change: 1.25
    Ensembl ID: ENSG00000166603
  • Gene Symbol: TRGV8 (ENSG00000211696)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211696
  • Gene Symbol: SNORA65 (ENSG00000201302)
    Fold Change: 1.25
    Ensembl ID: ENSG00000201302
  • Gene Symbol: IGLV3 27 (ENSG00000211658)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211658
  • Gene Symbol: IGLV2 33 (ENSG00000211656)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211656
  • Gene Symbol: FOXN3 AS2 (ENSG00000259073)
    Fold Change: 1.25
    Ensembl ID: ENSG00000259073
  • Gene Symbol: OR1I1 (ENSG00000094661)
    Fold Change: 1.25
    Ensembl ID: ENSG00000094661
  • Gene Symbol: CT83 (ENSG00000204019)
    Fold Change: 1.25
    Ensembl ID: ENSG00000204019
  • Gene Symbol: IFNA21 (ENSG00000137080)
    Fold Change: 1.25
    Ensembl ID: ENSG00000137080
  • Gene Symbol: IVL (ENSG00000163207)
    Fold Change: 1.25
    Ensembl ID: ENSG00000163207
  • Gene Symbol: KLK8 (ENSG00000129455)
    Fold Change: 1.25
    Ensembl ID: ENSG00000129455
  • Gene Symbol: OR5H1 (ENSG00000231192)
    Fold Change: 1.25
    Ensembl ID: ENSG00000231192
  • Gene Symbol: RNU5E 1 (ENSG00000199347)
    Fold Change: 1.25
    Ensembl ID: ENSG00000199347
  • Gene Symbol: RNU5B 1 (ENSG00000200156)
    Fold Change: 1.25
    Ensembl ID: ENSG00000200156
  • Gene Symbol: IGHV4 30 2 (ENSG00000231475)
    Fold Change: 1.25
    Ensembl ID: ENSG00000231475
  • Gene Symbol: TRBV23 1 (ENSG00000211749)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211749
  • Gene Symbol: IGLV4 60 (ENSG00000211639)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211639
  • Gene Symbol: OR5P2 (ENSG00000183303)
    Fold Change: 1.25
    Ensembl ID: ENSG00000183303
  • Gene Symbol: OR10G8 (ENSG00000234560)
    Fold Change: 1.25
    Ensembl ID: ENSG00000234560
  • Gene Symbol: HPYR1 (ENSG00000253521)
    Fold Change: 1.25
    Ensembl ID: ENSG00000253521
  • Gene Symbol: OR7A17 (ENSG00000185385)
    Fold Change: 1.25
    Ensembl ID: ENSG00000185385
  • Gene Symbol: TRBV7 7 (ENSG00000253291)
    Fold Change: 1.25
    Ensembl ID: ENSG00000253291
  • Gene Symbol: TRAV36DV7 (ENSG00000211815)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211815
  • Gene Symbol: TRAV20 (ENSG00000211800)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211800
  • Gene Symbol: TRAV13 2 (ENSG00000211791)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211791
  • Gene Symbol: IGLV3 10 (ENSG00000211669)
    Fold Change: 1.25
    Ensembl ID: ENSG00000211669
  • Gene Symbol: UBQLN3 (ENSG00000175520)
    Fold Change: 1.25
    Ensembl ID: ENSG00000175520
  • Gene Symbol: OR4K1 (ENSG00000155249)
    Fold Change: 1.25
    Ensembl ID: ENSG00000155249
  • Gene Symbol: CGB2 (ENSG00000104818)
    Fold Change: 1.25
    Ensembl ID: ENSG00000104818

Gene ID: A unique numerical identifier for this specific gene.
Symbol: Shortened abbreviation or name that represents this gene.
Ensembl Gene ID: A unique identifier assigned by Ensembl for genomic data mapping.
Fold Change: Indicates the ratio of the gene's expression level in neoplastic cell cell compared to a baseline. A fold change greater than 1 suggests significant gene expression.

Gene ID: A unique numerical identifier for this specific gene.
Symbol: Shortened abbreviation or name that represents this gene.
Ensembl Gene ID: A unique identifier assigned by Ensembl for genomic data mapping.
Fold Change: Indicates the ratio of the gene's expression level in neoplastic cell cell compared to a baseline. A fold change greater than 1 suggests significant gene expression.
**Key Characteristics** The neoplastic cell has several key characteristics that distinguish it from normal cells: 1. **Dysregulation of cell proliferation**: Neoplastic cells exhibit uncontrolled growth and division, leading to an increase in cell numbers. 2. **Dysregulation of programmed cell death**: Neoplastic cells often exhibit a decrease in programmed cell death, allowing them to survive and proliferate unchecked. 3. **Abnormal gene expression**: Neoplastic cells often exhibit altered gene expression patterns, leading to changes in cellular behavior and function. 4. **Loss of normal cellular functions**: Neoplastic cells often lose normal cellular functions, such as differentiation, migration, and apoptosis. 5. **Increased resistance to apoptosis**: Neoplastic cells often develop mechanisms to evade apoptosis, allowing them to survive and proliferate. **Clinical Significance** Neoplastic cells have significant clinical implications, including: 1. **Cancer development**: Neoplastic cells can lead to the development of cancer, a group of diseases characterized by uncontrolled cell growth and division. 2. **Tumor progression**: Neoplastic cells can progress to more aggressive forms of cancer, leading to increased morbidity and mortality. 3. **Metastasis**: Neoplastic cells can metastasize, or spread, to other parts of the body, leading to the formation of secondary tumors. 4. **Resistance to therapy**: Neoplastic cells can develop resistance to chemotherapy and other therapeutic interventions, making treatment challenging. 5. **Immunosuppression**: Neoplastic cells can suppress the immune system, making it difficult for the body to recognize and eliminate the tumor. **Genes Associated with Neoplastic Cells** Several genes have been associated with neoplastic cells, including: 1. **FBXO31**: A gene involved in the regulation of cell proliferation and apoptosis. 2. **TTN**: A gene involved in the regulation of cardiac muscle cell development and contraction. 3. **PTPRS**: A gene involved in the regulation of neuronal cell development and function. 4. **TAS2R13**: A gene involved in the regulation of bitter taste perception. 5. **OR4D2**: A gene involved in the regulation of olfactory perception. 6. **TP53TG3**: A gene involved in the regulation of cellular response to DNA damage. 7. **TAS2R9**: A gene involved in the regulation of bitter taste perception. 8. **TAS2R43**: A gene involved in the regulation of bitter taste perception. 9. **DEFA4**: A gene involved in the regulation of antimicrobial peptides and innate immune response. 10. **IFNA5**: A gene involved in the regulation of interferon signaling and innate immune response. These genes play important roles in regulating cellular behavior and function, and their dysregulation can contribute to the development of neoplastic cells and cancer.