Cell ID: CL0002062

Cell Name: pulmonary alveolar type 1 cell

CSI Thresholds:

Select	Context	Threshold
	Overall	10.9772
	Upper lobe of right lung	367.9124
	Upper lobe of right lung + Healthy	367.9070
	Middle lobe of right lung + Healthy	225.4663
	Middle lobe of right lung	225.4483
	Lower lobe of right lung + Healthy	220.0259
	Lower lobe of right lung	219.9949
	Upper lobe of left lung + Healthy	160.0163
	Upper lobe of left lung	159.9878
	Alveolus of lung + Healthy	141.0855
	Alveolus of lung + Pulmonary emphysema	122.7798
	Pulmonary emphysema	122.2942
	Alveolus of lung	116.5046
	Lingula of left lung	63.0849
	Lingula of left lung + Healthy	62.6181
	Lung adenocarcinoma	44.3725
	Pancreas + Healthy	42.3891
	Pancreas	42.0532
	Lung parenchyma + Healthy	40.3342
	Alveolar sac	31.3841
	Alveolar sac + Healthy	31.2100
	Respiratory airway	30.5079
	Respiratory airway + Healthy	30.3739
	Intestine	29.6497
	Lung parenchyma	28.2190
	Colon + Healthy	27.1727
	Lung + Lymphangioleiomyomatosis	21.7827
	Lymphangioleiomyomatosis	21.7701
	Lymph node	15.6770
	Colon	14.7835
	Anencephaly	13.9855
	Lung + Anencephaly	13.9638
	Lung + COVID-19	11.3595
	Lung parenchyma + Chronic obstructive pulmonary disease	10.4691
	Chronic obstructive pulmonary disease	10.2694
	Lung + Hypersensitivity pneumonitis	9.8748
	Hypersensitivity pneumonitis	9.8476
	Liver	9.4648
	Healthy	9.2804
	COVID-19	9.0970
	Liver + Healthy	8.9169
	Lower lobe of left lung + Healthy	8.5586
	Lower lobe of left lung	8.5568
	Lung + Pulmonary sarcoidosis	7.5987
	Pulmonary sarcoidosis	7.5876
	Intestine + Healthy	6.7974
	Lung	6.3686
	Non-small cell lung carcinoma	6.2038
	Lung + Non-small cell lung carcinoma	6.1910
	Lung + Non-specific interstitial pneumonia	6.1386
	Non-specific interstitial pneumonia	6.1333
	Lung + Squamous cell lung carcinoma	5.1428
	Squamous cell lung carcinoma	5.1325
	Lymph node + Lung adenocarcinoma	4.8315
	Lung + Interstitial lung disease	4.3113
	Interstitial lung disease	4.2968
	Lung large cell carcinoma	4.2457
	Lung + Lung large cell carcinoma	4.2156
	Lung + Lung adenocarcinoma	3.7034
	Pneumonia	3.5480
	Lung + Pneumonia	3.4945
	Lung + Healthy	3.4114
	Lung + Pleomorphic carcinoma	3.3375
	Pleomorphic carcinoma	3.3373
	Pulmonary fibrosis	3.1603
	Lung + Pulmonary fibrosis	3.1419
	Lung + Chronic obstructive pulmonary disease	2.6058
	Bronchus	2.1246
	Bronchus + Healthy	2.1099
	Chronic rhinitis	1.3804
	Nose + Chronic rhinitis	1.3161
	Nose	1.2812

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A squamous pulmonary alveolar epithelial cell that is flattened and branched. A pulmonary alveolar type 1 cell covers more than 98% of the alveolar surface. This large cell has thin (50-100 nm) cytoplasmic extensions to form the air-blood barrier essential for normal gas exchange.

Synonyms: lung type 1 cells, membranous pneumocytes, pulmonary alveolar type I cell, small alveolar cells, squamous alveolar cell, squamous alveolar lining cell, type 1 alveolar epithelial cells, type 1 pneumocyte, type I alveolar cells, type I alveolar epithelial cells, type I pneumocyte, AT1, ATI