Details for: CL0002204

Cell ID: CL0002204

Cell Name: brush cell

Marker Score Threshold: 913
(Derived using integrated single-cell and genomic data)

Description: A cell type found in the gastrointestinal and respiratory tracts that is characterized by the presence of a tuft of blunt, squat microvilli (120-140 per cell). Function of this cell type is not known.

Synonyms: caveolated cell, fibrillovesicular cell, multivesicular cell, tuft cell

Genes (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Gene Symbol: RNU1 14P (ENSG00000199629)
    Fold Change: 3.2
    Ensembl ID: ENSG00000199629
  • Gene Symbol: TTTY5 (ENSG00000215560)
    Fold Change: 3.2
    Ensembl ID: ENSG00000215560
  • Gene Symbol: CSPG4P1Y (ENSG00000240450)
    Fold Change: 3.2
    Ensembl ID: ENSG00000240450
  • Gene Symbol: TTTY20 (ENSG00000232808)
    Fold Change: 3.2
    Ensembl ID: ENSG00000232808
  • Gene Symbol: TTTY3B (ENSG00000280961)
    Fold Change: 3.2
    Ensembl ID: ENSG00000280961
  • Gene Symbol: CT45A6 (ENSG00000278289)
    Fold Change: 3.2
    Ensembl ID: ENSG00000278289
  • Gene Symbol: MIR509 2 (ENSG00000212013)
    Fold Change: 3.2
    Ensembl ID: ENSG00000212013
  • Gene Symbol: CXorf51A (ENSG00000224440)
    Fold Change: 3.2
    Ensembl ID: ENSG00000224440
  • Gene Symbol: VTRNA3 1P (ENSG00000199422)
    Fold Change: 3.2
    Ensembl ID: ENSG00000199422
  • Gene Symbol: RNU7 6P (ENSG00000252654)
    Fold Change: 3.2
    Ensembl ID: ENSG00000252654
  • Gene Symbol: RNU7 22P (ENSG00000252482)
    Fold Change: 3.2
    Ensembl ID: ENSG00000252482
  • Gene Symbol: RNU7 53P (ENSG00000252514)
    Fold Change: 3.2
    Ensembl ID: ENSG00000252514
  • Gene Symbol: RNU7 66P (ENSG00000238949)
    Fold Change: 3.2
    Ensembl ID: ENSG00000238949
  • Gene Symbol: RNU7 74P (ENSG00000239010)
    Fold Change: 3.2
    Ensembl ID: ENSG00000239010
  • Gene Symbol: RNY4P14 (ENSG00000200526)
    Fold Change: 3.2
    Ensembl ID: ENSG00000200526
  • Gene Symbol: MIR4317 (ENSG00000283532)
    Fold Change: 3.2
    Ensembl ID: ENSG00000283532
  • Gene Symbol: MIR4283 1 (ENSG00000264426)
    Fold Change: 3.2
    Ensembl ID: ENSG00000264426
  • Gene Symbol: MIR3649 (ENSG00000266043)
    Fold Change: 3.2
    Ensembl ID: ENSG00000266043
  • Gene Symbol: MIR4483 (ENSG00000283656)
    Fold Change: 3.2
    Ensembl ID: ENSG00000283656
  • Gene Symbol: MIR3974 (ENSG00000283665)
    Fold Change: 3.2
    Ensembl ID: ENSG00000283665
  • Gene Symbol: MIR3977 (ENSG00000283359)
    Fold Change: 3.2
    Ensembl ID: ENSG00000283359
  • Gene Symbol: MIR4771 1 (ENSG00000264793)
    Fold Change: 3.2
    Ensembl ID: ENSG00000264793
  • Gene Symbol: RNY3P7 (ENSG00000206800)
    Fold Change: 3.2
    Ensembl ID: ENSG00000206800
  • Gene Symbol: RNY4P30 (ENSG00000222148)
    Fold Change: 3.2
    Ensembl ID: ENSG00000222148
  • Gene Symbol: RNU4 10P (ENSG00000201253)
    Fold Change: 3.2
    Ensembl ID: ENSG00000201253
  • Gene Symbol: RNA5SP18 (ENSG00000212237)
    Fold Change: 3.2
    Ensembl ID: ENSG00000212237
  • Gene Symbol: RNA5SP45 (ENSG00000252563)
    Fold Change: 3.2
    Ensembl ID: ENSG00000252563
  • Gene Symbol: RNA5SP121 (ENSG00000252346)
    Fold Change: 3.2
    Ensembl ID: ENSG00000252346
  • Gene Symbol: RNA5SP136 (ENSG00000222838)
    Fold Change: 3.2
    Ensembl ID: ENSG00000222838
  • Gene Symbol: RNA5SP225 (ENSG00000222806)
    Fold Change: 3.2
    Ensembl ID: ENSG00000222806
  • Gene Symbol: RNA5SP231 (ENSG00000222428)
    Fold Change: 3.2
    Ensembl ID: ENSG00000222428
  • Gene Symbol: RNA5SP281 (ENSG00000252313)
    Fold Change: 3.2
    Ensembl ID: ENSG00000252313
  • Gene Symbol: RNA5SP286 (ENSG00000212454)
    Fold Change: 3.2
    Ensembl ID: ENSG00000212454
  • Gene Symbol: RNA5SP287 (ENSG00000252167)
    Fold Change: 3.2
    Ensembl ID: ENSG00000252167
  • Gene Symbol: RNA5SP502 (ENSG00000199564)
    Fold Change: 3.2
    Ensembl ID: ENSG00000199564
  • Gene Symbol: RNA5SP507 (ENSG00000200473)
    Fold Change: 3.2
    Ensembl ID: ENSG00000200473
  • Gene Symbol: RNA5SP299 (ENSG00000212505)
    Fold Change: 3.2
    Ensembl ID: ENSG00000212505
  • Gene Symbol: RNA5SP329 (ENSG00000202147)
    Fold Change: 3.2
    Ensembl ID: ENSG00000202147
  • Gene Symbol: RNA5SP353 (ENSG00000201476)
    Fold Change: 3.2
    Ensembl ID: ENSG00000201476
  • Gene Symbol: RNA5SP359 (ENSG00000201708)
    Fold Change: 3.2
    Ensembl ID: ENSG00000201708
  • Gene Symbol: RNA5SP369 (ENSG00000223046)
    Fold Change: 3.2
    Ensembl ID: ENSG00000223046
  • Gene Symbol: RNA5SP382 (ENSG00000200225)
    Fold Change: 3.2
    Ensembl ID: ENSG00000200225
  • Gene Symbol: RNA5SP428 (ENSG00000201999)
    Fold Change: 3.2
    Ensembl ID: ENSG00000201999
  • Gene Symbol: RNA5SP441 (ENSG00000252618)
    Fold Change: 3.2
    Ensembl ID: ENSG00000252618
  • Gene Symbol: RNA5SP451 (ENSG00000222520)
    Fold Change: 3.2
    Ensembl ID: ENSG00000222520
  • Gene Symbol: RNA5SP481 (ENSG00000252623)
    Fold Change: 3.2
    Ensembl ID: ENSG00000252623
  • Gene Symbol: RNU6 63P (ENSG00000252499)
    Fold Change: 3.2
    Ensembl ID: ENSG00000252499
  • Gene Symbol: RNU6 66P (ENSG00000200267)
    Fold Change: 3.2
    Ensembl ID: ENSG00000200267
  • Gene Symbol: RNU6 71P (ENSG00000207203)
    Fold Change: 3.2
    Ensembl ID: ENSG00000207203
  • Gene Symbol: RNY1P7 (ENSG00000207474)
    Fold Change: 3.2
    Ensembl ID: ENSG00000207474
  • Gene Symbol: RNY1P8 (ENSG00000206697)
    Fold Change: 3.2
    Ensembl ID: ENSG00000206697
  • Gene Symbol: RNY3P4 (ENSG00000207157)
    Fold Change: 3.2
    Ensembl ID: ENSG00000207157
  • Gene Symbol: RNY4P28 (ENSG00000202151)
    Fold Change: 3.2
    Ensembl ID: ENSG00000202151
  • Gene Symbol: RNU5F 6P (ENSG00000199849)
    Fold Change: 3.2
    Ensembl ID: ENSG00000199849
  • Gene Symbol: RNU5F 7P (ENSG00000200566)
    Fold Change: 3.2
    Ensembl ID: ENSG00000200566
  • Gene Symbol: RNU5E 7P (ENSG00000202160)
    Fold Change: 3.2
    Ensembl ID: ENSG00000202160
  • Gene Symbol: PLSCR5 AS1 (ENSG00000241457)
    Fold Change: 3.2
    Ensembl ID: ENSG00000241457
  • Gene Symbol: MIR6862 2 (ENSG00000278340)
    Fold Change: 3.2
    Ensembl ID: ENSG00000278340
  • Gene Symbol: MIR8071 2 (ENSG00000277030)
    Fold Change: 3.2
    Ensembl ID: ENSG00000277030
  • Gene Symbol: RNU6 22P (ENSG00000207083)
    Fold Change: 3.2
    Ensembl ID: ENSG00000207083
  • Gene Symbol: RNA5SP130 (ENSG00000201301)
    Fold Change: 3.2
    Ensembl ID: ENSG00000201301
  • Gene Symbol: RNU7 164P (ENSG00000238730)
    Fold Change: 3.2
    Ensembl ID: ENSG00000238730
  • Gene Symbol: RNU7 167P (ENSG00000238584)
    Fold Change: 3.2
    Ensembl ID: ENSG00000238584
  • Gene Symbol: RN7SKP44 (ENSG00000200472)
    Fold Change: 3.2
    Ensembl ID: ENSG00000200472
  • Gene Symbol: RN7SKP59 (ENSG00000222452)
    Fold Change: 3.2
    Ensembl ID: ENSG00000222452
  • Gene Symbol: RN7SKP155 (ENSG00000251840)
    Fold Change: 3.2
    Ensembl ID: ENSG00000251840
  • Gene Symbol: RN7SKP262 (ENSG00000222950)
    Fold Change: 3.2
    Ensembl ID: ENSG00000222950
  • Gene Symbol: RN7SKP289 (ENSG00000253053)
    Fold Change: 3.2
    Ensembl ID: ENSG00000253053
  • Gene Symbol: RN7SL87P (ENSG00000239390)
    Fold Change: 3.2
    Ensembl ID: ENSG00000239390
  • Gene Symbol: RN7SL140P (ENSG00000266059)
    Fold Change: 3.2
    Ensembl ID: ENSG00000266059
  • Gene Symbol: RN7SL147P (ENSG00000263988)
    Fold Change: 3.2
    Ensembl ID: ENSG00000263988
  • Gene Symbol: RN7SL191P (ENSG00000241198)
    Fold Change: 3.2
    Ensembl ID: ENSG00000241198
  • Gene Symbol: RN7SL214P (ENSG00000242066)
    Fold Change: 3.2
    Ensembl ID: ENSG00000242066
  • Gene Symbol: RN7SL248P (ENSG00000274186)
    Fold Change: 3.2
    Ensembl ID: ENSG00000274186
  • Gene Symbol: RN7SL271P (ENSG00000239250)
    Fold Change: 3.2
    Ensembl ID: ENSG00000239250
  • Gene Symbol: RN7SL361P (ENSG00000242158)
    Fold Change: 3.2
    Ensembl ID: ENSG00000242158
  • Gene Symbol: RN7SL564P (ENSG00000240606)
    Fold Change: 3.2
    Ensembl ID: ENSG00000240606
  • Gene Symbol: RN7SL647P (ENSG00000243957)
    Fold Change: 3.2
    Ensembl ID: ENSG00000243957
  • Gene Symbol: RN7SL722P (ENSG00000273940)
    Fold Change: 3.2
    Ensembl ID: ENSG00000273940
  • Gene Symbol: RN7SL759P (ENSG00000278497)
    Fold Change: 3.2
    Ensembl ID: ENSG00000278497
  • Gene Symbol: RNU4ATAC4P (ENSG00000252116)
    Fold Change: 3.2
    Ensembl ID: ENSG00000252116
  • Gene Symbol: RNU4ATAC6P (ENSG00000252401)
    Fold Change: 3.2
    Ensembl ID: ENSG00000252401
  • Gene Symbol: RNU6ATAC21P (ENSG00000221583)
    Fold Change: 3.2
    Ensembl ID: ENSG00000221583
  • Gene Symbol: RNU6ATAC28P (ENSG00000238561)
    Fold Change: 3.2
    Ensembl ID: ENSG00000238561
  • Gene Symbol: RNU6ATAC40P (ENSG00000221507)
    Fold Change: 3.2
    Ensembl ID: ENSG00000221507
  • Gene Symbol: RNU4 30P (ENSG00000222177)
    Fold Change: 3.2
    Ensembl ID: ENSG00000222177
  • Gene Symbol: RNU6 113P (ENSG00000252462)
    Fold Change: 3.2
    Ensembl ID: ENSG00000252462
  • Gene Symbol: RNU6 120P (ENSG00000251886)
    Fold Change: 3.2
    Ensembl ID: ENSG00000251886
  • Gene Symbol: RNU6 131P (ENSG00000212446)
    Fold Change: 3.2
    Ensembl ID: ENSG00000212446
  • Gene Symbol: RNU6 148P (ENSG00000252823)
    Fold Change: 3.2
    Ensembl ID: ENSG00000252823
  • Gene Symbol: RNU6 163P (ENSG00000207124)
    Fold Change: 3.2
    Ensembl ID: ENSG00000207124
  • Gene Symbol: RNU6 214P (ENSG00000206857)
    Fold Change: 3.2
    Ensembl ID: ENSG00000206857
  • Gene Symbol: RNU6 219P (ENSG00000201598)
    Fold Change: 3.2
    Ensembl ID: ENSG00000201598
  • Gene Symbol: RNU6 225P (ENSG00000207343)
    Fold Change: 3.2
    Ensembl ID: ENSG00000207343
  • Gene Symbol: RNU6 241P (ENSG00000212450)
    Fold Change: 3.2
    Ensembl ID: ENSG00000212450
  • Gene Symbol: RNU6 279P (ENSG00000212599)
    Fold Change: 3.2
    Ensembl ID: ENSG00000212599
  • Gene Symbol: RNU6 369P (ENSG00000199385)
    Fold Change: 3.2
    Ensembl ID: ENSG00000199385
  • Gene Symbol: RNU6 413P (ENSG00000206842)
    Fold Change: 3.2
    Ensembl ID: ENSG00000206842
  • Gene Symbol: RNU6 470P (ENSG00000251763)
    Fold Change: 3.2
    Ensembl ID: ENSG00000251763
  • Gene Symbol: RNU6 506P (ENSG00000252362)
    Fold Change: 3.2
    Ensembl ID: ENSG00000252362

Gene ID: A unique numerical identifier for this specific gene.
Symbol: Shortened abbreviation or name that represents this gene.
Ensembl Gene ID: A unique identifier assigned by Ensembl for genomic data mapping.
Fold Change: Indicates the ratio of the gene's expression level in brush cell cell compared to a baseline. A fold change greater than 1 suggests significant gene expression.

Gene ID: A unique numerical identifier for this specific gene.
Symbol: Shortened abbreviation or name that represents this gene.
Ensembl Gene ID: A unique identifier assigned by Ensembl for genomic data mapping.
Fold Change: Indicates the ratio of the gene's expression level in brush cell cell compared to a baseline. A fold change greater than 1 suggests significant gene expression.
**Key Characteristics** The brush cell is distinguished by the following key characteristics: 1. **Microvilli structure**: Brush cells are characterized by the presence of a tuft of blunt, squat microvilli, with approximately 120-140 microvilli per cell. 2. **Location**: Brush cells are found in the gastrointestinal and respiratory tracts. 3. **Cell morphology**: The cell morphology is not well-defined, but it is generally considered to be a type of epithelial cell. 4. **Function**: The function of brush cells is not known, and it is unclear whether they play a role in absorption, secretion, or other cellular processes. **Clinical Significance** The clinical significance of brush cells is not well understood, and further research is needed to determine their role in human health and disease. However, the following potential clinical implications have been proposed: 1. **Gastrointestinal disorders**: Brush cells may play a role in the pathogenesis of gastrointestinal disorders, such as inflammatory bowel disease or gastroesophageal reflux disease. 2. **Respiratory diseases**: Brush cells may also be involved in the pathogenesis of respiratory diseases, such as asthma or chronic obstructive pulmonary disease. 3. **Cancer**: The expression of certain genes associated with brush cells, such as TTTY5 and CSPG4P1Y, has been linked to cancer, suggesting that brush cells may play a role in tumorigenesis. 4. **Neurological disorders**: Some studies have suggested that brush cells may be involved in the pathogenesis of neurological disorders, such as Alzheimer's disease or Parkinson's disease. Overall, further research is needed to fully understand the role of brush cells in human health and disease, and to determine their potential clinical significance.