Cell ID: CL0002363

Cell Name: keratocyte

CSI Thresholds:

Select	Context	Threshold
	Overall	15.8648
	Sclera	73.3115
	Sclera + Healthy	73.3107
	Eye + Healthy	31.4188
	Eye	31.3379
	Cornea + Healthy	29.6162
	Cornea	29.6112
	Conjunctiva	18.5313
	Conjunctiva + Healthy	18.5313
	Healthy	15.7203

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(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate.

Synonyms: corneal fibroblast, corneal keratocyte