Cell ID: CL0002410

Cell Name: pancreatic stellate cell

CSI Thresholds:

Select	Context	Threshold
	Overall	12.5936
	Pancreas	139.5773
	Pancreas + Healthy	137.7375
	Islet of Langerhans	71.3301
	Type 1 diabetes mellitus	46.9652
	Islet of Langerhans + Type 1 diabetes mellitus	46.9652
	Exocrine pancreas	24.8053
	Exocrine pancreas + Healthy	24.8053
	Islet of Langerhans + Healthy	16.8263
	Healthy	13.5172

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(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A cell that is found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and has long cytoplasmic processes that encircle the base of the acinus. Expresses several intermediate filament proteins including vimentin and nestin. Shares many of the characteristics of hepatatic stellate cells, but not stellate cells of the central nervous system. Upon activation, this cell type undergoes morphological and gene expression changes that make the cell suggestive of being a type of myofibroblast.

Synonyms: PaSC, pancreas stellate cell