Details for: CL0002503

Cell ID: CL0002503

Cell Name: adventitial cell

Marker Score Threshold: 247
(Derived using integrated single-cell and genomic data)

Description: A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc

Genes (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Gene Symbol: ACTB (ENSG00000075624)
    Fold Change: 3.16
    Ensembl ID: ENSG00000075624
  • Gene Symbol: B2M (ENSG00000166710)
    Fold Change: 3.11
    Ensembl ID: ENSG00000166710
  • Gene Symbol: ACTG1 (ENSG00000184009)
    Fold Change: 2.95
    Ensembl ID: ENSG00000184009
  • Gene Symbol: ATP5F1E (ENSG00000124172)
    Fold Change: 2.66
    Ensembl ID: ENSG00000124172
  • Gene Symbol: RHOA (ENSG00000067560)
    Fold Change: 2.58
    Ensembl ID: ENSG00000067560
  • Gene Symbol: ATP5MC2 (ENSG00000135390)
    Fold Change: 2.42
    Ensembl ID: ENSG00000135390
  • Gene Symbol: ARF1 (ENSG00000143761)
    Fold Change: 2.37
    Ensembl ID: ENSG00000143761
  • Gene Symbol: ATP5ME (ENSG00000169020)
    Fold Change: 2.33
    Ensembl ID: ENSG00000169020
  • Gene Symbol: ANXA2 (ENSG00000182718)
    Fold Change: 2.26
    Ensembl ID: ENSG00000182718
  • Gene Symbol: ATP5PF (ENSG00000154723)
    Fold Change: 2.23
    Ensembl ID: ENSG00000154723
  • Gene Symbol: ATP5F1B (ENSG00000110955)
    Fold Change: 2.22
    Ensembl ID: ENSG00000110955
  • Gene Symbol: ATP5F1D (ENSG00000099624)
    Fold Change: 2.19
    Ensembl ID: ENSG00000099624
  • Gene Symbol: ANXA5 (ENSG00000164111)
    Fold Change: 2.16
    Ensembl ID: ENSG00000164111
  • Gene Symbol: ATP5MC3 (ENSG00000154518)
    Fold Change: 2.14
    Ensembl ID: ENSG00000154518
  • Gene Symbol: ATP5F1A (ENSG00000152234)
    Fold Change: 2.09
    Ensembl ID: ENSG00000152234
  • Gene Symbol: APRT (ENSG00000198931)
    Fold Change: 2.07
    Ensembl ID: ENSG00000198931
  • Gene Symbol: ANXA1 (ENSG00000135046)
    Fold Change: 2.04
    Ensembl ID: ENSG00000135046
  • Gene Symbol: SLC25A5 (ENSG00000005022)
    Fold Change: 2.01
    Ensembl ID: ENSG00000005022
  • Gene Symbol: APLP2 (ENSG00000084234)
    Fold Change: 2.01
    Ensembl ID: ENSG00000084234
  • Gene Symbol: ARF4 (ENSG00000168374)
    Fold Change: 1.9
    Ensembl ID: ENSG00000168374
  • Gene Symbol: ATRX (ENSG00000085224)
    Fold Change: 1.89
    Ensembl ID: ENSG00000085224
  • Gene Symbol: ATP5PO (ENSG00000241837)
    Fold Change: 1.89
    Ensembl ID: ENSG00000241837
  • Gene Symbol: RHOB (ENSG00000143878)
    Fold Change: 1.88
    Ensembl ID: ENSG00000143878
  • Gene Symbol: ATF4 (ENSG00000128272)
    Fold Change: 1.87
    Ensembl ID: ENSG00000128272
  • Gene Symbol: ATP1A1 (ENSG00000163399)
    Fold Change: 1.87
    Ensembl ID: ENSG00000163399
  • Gene Symbol: ATP5F1C (ENSG00000165629)
    Fold Change: 1.86
    Ensembl ID: ENSG00000165629
  • Gene Symbol: ADD3 (ENSG00000148700)
    Fold Change: 1.82
    Ensembl ID: ENSG00000148700
  • Gene Symbol: TLE5 (ENSG00000104964)
    Fold Change: 1.82
    Ensembl ID: ENSG00000104964
  • Gene Symbol: ATP5PB (ENSG00000116459)
    Fold Change: 1.78
    Ensembl ID: ENSG00000116459
  • Gene Symbol: ARHGDIA (ENSG00000141522)
    Fold Change: 1.76
    Ensembl ID: ENSG00000141522
  • Gene Symbol: APOD (ENSG00000189058)
    Fold Change: 1.73
    Ensembl ID: ENSG00000189058
  • Gene Symbol: ATP5MC1 (ENSG00000159199)
    Fold Change: 1.71
    Ensembl ID: ENSG00000159199
  • Gene Symbol: ANXA11 (ENSG00000122359)
    Fold Change: 1.68
    Ensembl ID: ENSG00000122359
  • Gene Symbol: ATP6V0B (ENSG00000117410)
    Fold Change: 1.68
    Ensembl ID: ENSG00000117410
  • Gene Symbol: ADH1B (ENSG00000196616)
    Fold Change: 1.65
    Ensembl ID: ENSG00000196616
  • Gene Symbol: ADH5 (ENSG00000197894)
    Fold Change: 1.63
    Ensembl ID: ENSG00000197894
  • Gene Symbol: ALDOA (ENSG00000149925)
    Fold Change: 1.63
    Ensembl ID: ENSG00000149925
  • Gene Symbol: ANXA7 (ENSG00000138279)
    Fold Change: 1.63
    Ensembl ID: ENSG00000138279
  • Gene Symbol: ADD1 (ENSG00000087274)
    Fold Change: 1.61
    Ensembl ID: ENSG00000087274
  • Gene Symbol: ATP1B3 (ENSG00000069849)
    Fold Change: 1.6
    Ensembl ID: ENSG00000069849
  • Gene Symbol: ASAH1 (ENSG00000104763)
    Fold Change: 1.59
    Ensembl ID: ENSG00000104763
  • Gene Symbol: APP (ENSG00000142192)
    Fold Change: 1.57
    Ensembl ID: ENSG00000142192
  • Gene Symbol: ACADVL (ENSG00000072778)
    Fold Change: 1.51
    Ensembl ID: ENSG00000072778
  • Gene Symbol: PLIN2 (ENSG00000147872)
    Fold Change: 1.51
    Ensembl ID: ENSG00000147872
  • Gene Symbol: AUP1 (ENSG00000115307)
    Fold Change: 1.49
    Ensembl ID: ENSG00000115307
  • Gene Symbol: RERE (ENSG00000142599)
    Fold Change: 1.47
    Ensembl ID: ENSG00000142599
  • Gene Symbol: APEX1 (ENSG00000100823)
    Fold Change: 1.45
    Ensembl ID: ENSG00000100823
  • Gene Symbol: ASPH (ENSG00000198363)
    Fold Change: 1.44
    Ensembl ID: ENSG00000198363
  • Gene Symbol: ZFHX3 (ENSG00000140836)
    Fold Change: 1.44
    Ensembl ID: ENSG00000140836
  • Gene Symbol: AMD1 (ENSG00000123505)
    Fold Change: 1.43
    Ensembl ID: ENSG00000123505
  • Gene Symbol: ALDH2 (ENSG00000111275)
    Fold Change: 1.42
    Ensembl ID: ENSG00000111275
  • Gene Symbol: AEBP1 (ENSG00000106624)
    Fold Change: 1.41
    Ensembl ID: ENSG00000106624
  • Gene Symbol: ARHGDIB (ENSG00000111348)
    Fold Change: 1.4
    Ensembl ID: ENSG00000111348
  • Gene Symbol: AOX1 (ENSG00000138356)
    Fold Change: 1.38
    Ensembl ID: ENSG00000138356
  • Gene Symbol: ANXA6 (ENSG00000197043)
    Fold Change: 1.38
    Ensembl ID: ENSG00000197043
  • Gene Symbol: BLVRB (ENSG00000090013)
    Fold Change: 1.36
    Ensembl ID: ENSG00000090013
  • Gene Symbol: ATOX1 (ENSG00000177556)
    Fold Change: 1.35
    Ensembl ID: ENSG00000177556
  • Gene Symbol: ANXA4 (ENSG00000196975)
    Fold Change: 1.34
    Ensembl ID: ENSG00000196975
  • Gene Symbol: ATP6V1E1 (ENSG00000131100)
    Fold Change: 1.34
    Ensembl ID: ENSG00000131100
  • Gene Symbol: ADAR (ENSG00000160710)
    Fold Change: 1.32
    Ensembl ID: ENSG00000160710
  • Gene Symbol: BNIP2 (ENSG00000140299)
    Fold Change: 1.32
    Ensembl ID: ENSG00000140299
  • Gene Symbol: ARF5 (ENSG00000004059)
    Fold Change: 1.31
    Ensembl ID: ENSG00000004059
  • Gene Symbol: AXL (ENSG00000167601)
    Fold Change: 1.3
    Ensembl ID: ENSG00000167601
  • Gene Symbol: ACP1 (ENSG00000143727)
    Fold Change: 1.3
    Ensembl ID: ENSG00000143727
  • Gene Symbol: RHOC (ENSG00000155366)
    Fold Change: 1.3
    Ensembl ID: ENSG00000155366
  • Gene Symbol: ARL2 (ENSG00000213465)
    Fold Change: 1.28
    Ensembl ID: ENSG00000213465
  • Gene Symbol: AP2B1 (ENSG00000006125)
    Fold Change: 1.28
    Ensembl ID: ENSG00000006125
  • Gene Symbol: ATF3 (ENSG00000162772)
    Fold Change: 1.27
    Ensembl ID: ENSG00000162772
  • Gene Symbol: ACTN4 (ENSG00000130402)
    Fold Change: 1.26
    Ensembl ID: ENSG00000130402
  • Gene Symbol: ATP6AP1 (ENSG00000071553)
    Fold Change: 1.26
    Ensembl ID: ENSG00000071553
  • Gene Symbol: BCL6 (ENSG00000113916)
    Fold Change: 1.26
    Ensembl ID: ENSG00000113916
  • Gene Symbol: ARF6 (ENSG00000165527)
    Fold Change: 1.19
    Ensembl ID: ENSG00000165527
  • Gene Symbol: BAG1 (ENSG00000107262)
    Fold Change: 1.18
    Ensembl ID: ENSG00000107262
  • Gene Symbol: ATP2B4 (ENSG00000058668)
    Fold Change: 1.18
    Ensembl ID: ENSG00000058668
  • Gene Symbol: ARL1 (ENSG00000120805)
    Fold Change: 1.17
    Ensembl ID: ENSG00000120805
  • Gene Symbol: ACAT1 (ENSG00000075239)
    Fold Change: 1.15
    Ensembl ID: ENSG00000075239
  • Gene Symbol: AAMP (ENSG00000127837)
    Fold Change: 1.15
    Ensembl ID: ENSG00000127837
  • Gene Symbol: AR (ENSG00000169083)
    Fold Change: 1.14
    Ensembl ID: ENSG00000169083
  • Gene Symbol: BIN1 (ENSG00000136717)
    Fold Change: 1.14
    Ensembl ID: ENSG00000136717
  • Gene Symbol: ATP2B1 (ENSG00000070961)
    Fold Change: 1.13
    Ensembl ID: ENSG00000070961
  • Gene Symbol: ATM (ENSG00000149311)
    Fold Change: 1.12
    Ensembl ID: ENSG00000149311
  • Gene Symbol: AKR1B1 (ENSG00000085662)
    Fold Change: 1.11
    Ensembl ID: ENSG00000085662
  • Gene Symbol: AK2 (ENSG00000004455)
    Fold Change: 1.11
    Ensembl ID: ENSG00000004455
  • Gene Symbol: BAX (ENSG00000087088)
    Fold Change: 1.11
    Ensembl ID: ENSG00000087088
  • Gene Symbol: PARP1 (ENSG00000143799)
    Fold Change: 1.11
    Ensembl ID: ENSG00000143799
  • Gene Symbol: ATP2A2 (ENSG00000174437)
    Fold Change: 1.1
    Ensembl ID: ENSG00000174437
  • Gene Symbol: ABCA1 (ENSG00000165029)
    Fold Change: 1.09
    Ensembl ID: ENSG00000165029
  • Gene Symbol: ALDH9A1 (ENSG00000143149)
    Fold Change: 1.09
    Ensembl ID: ENSG00000143149
  • Gene Symbol: ALDH1A1 (ENSG00000165092)
    Fold Change: 1.09
    Ensembl ID: ENSG00000165092
  • Gene Symbol: BAD (ENSG00000002330)
    Fold Change: 1.08
    Ensembl ID: ENSG00000002330
  • Gene Symbol: ARHGAP1 (ENSG00000175220)
    Fold Change: 1.08
    Ensembl ID: ENSG00000175220
  • Gene Symbol: ABCF1 (ENSG00000204574)
    Fold Change: 1.06
    Ensembl ID: ENSG00000204574
  • Gene Symbol: ARCN1 (ENSG00000095139)
    Fold Change: 1.04
    Ensembl ID: ENSG00000095139
  • Gene Symbol: GET3 (ENSG00000198356)
    Fold Change: 1.04
    Ensembl ID: ENSG00000198356
  • Gene Symbol: BMPR2 (ENSG00000204217)
    Fold Change: 1.04
    Ensembl ID: ENSG00000204217
  • Gene Symbol: ANPEP (ENSG00000166825)
    Fold Change: 1.02
    Ensembl ID: ENSG00000166825
  • Gene Symbol: BIRC2 (ENSG00000110330)
    Fold Change: 1.02
    Ensembl ID: ENSG00000110330
  • Gene Symbol: RND3 (ENSG00000115963)
    Fold Change: 1.02
    Ensembl ID: ENSG00000115963
  • Gene Symbol: AZGP1 (ENSG00000160862)
    Fold Change: 1
    Ensembl ID: ENSG00000160862
  • Gene Symbol: ARF3 (ENSG00000134287)
    Fold Change: N/A
    Ensembl ID: ENSG00000134287

Gene ID: A unique numerical identifier for this specific gene.
Symbol: Shortened abbreviation or name that represents this gene.
Ensembl Gene ID: A unique identifier assigned by Ensembl for genomic data mapping.
Fold Change: Indicates the ratio of the gene's expression level in adventitial cell cell compared to a baseline. A fold change greater than 1 suggests significant gene expression.

Gene ID: A unique numerical identifier for this specific gene.
Symbol: Shortened abbreviation or name that represents this gene.
Ensembl Gene ID: A unique identifier assigned by Ensembl for genomic data mapping.
Fold Change: Indicates the ratio of the gene's expression level in adventitial cell cell compared to a baseline. A fold change greater than 1 suggests significant gene expression.
**Key Characteristics** * Adventitial cell: Found in the adventitial layer of ductal structures such as the uterus, deferent duct, and biliary duct. * Involvement in cell-cell communication and cell-extracellular matrix interactions. * Regulation of actin dynamics, including regulation of apoptotic process, regulation of cell cycle, and regulation of nucleotide-excision repair. * Involvement in various signaling pathways, including MAPK signaling, Rho GTPase signaling, and NF-κB signaling. * Gene symbol: ACTB. * Ensembl ID: ENSG00000075624. **Clinical Significance** Adventitial cells have been implicated in various diseases and disorders, including: * Cancer: Adventitial cells have been shown to play a role in tumor progression and metastasis. * Inflammatory diseases: Adventitial cells have been implicated in the pathogenesis of inflammatory diseases such as rheumatoid arthritis and atherosclerosis. * Neurological disorders: Adventitial cells have been shown to play a role in the development and progression of neurological disorders such as Alzheimer's disease and Parkinson's disease. * Cardiovascular diseases: Adventitial cells have been implicated in the pathogenesis of cardiovascular diseases such as atherosclerosis and hypertension. The study of adventitial cells and their role in disease has the potential to lead to the development of new therapeutic strategies for the treatment of these diseases. For example, targeting the signaling pathways involved in adventitial cell function may provide a new approach for the treatment of cancer and inflammatory diseases. Additionally, the study of adventitial cells may also provide insights into the development and progression of neurological disorders. For example, understanding the role of adventitial cells in the development of Alzheimer's disease may lead to the development of new therapeutic strategies for the treatment of this disease. In summary, the study of adventitial cells and their role in disease has the potential to lead to the development of new therapeutic strategies for the treatment of various diseases. Further research is needed to fully understand the role of adventitial cells in disease and to develop effective treatments for these diseases.