Cell ID: CL0009011

Cell Name: transit amplifying cell of colon

CSI Thresholds:

Select	Context	Threshold
	Overall	32.0285
	Colonic epithelium + Healthy	361.0366
	Transverse colon + Healthy	309.5378
	Transverse colon	305.4413
	Ileum	98.2606
	Neuroendocrine carcinoma	98.0366
	Ileum + Neuroendocrine carcinoma	97.9403
	Colonic epithelium	88.3414
	Adenocarcinoma	84.7854
	Rectum + Adenocarcinoma	63.3473
	Rectum	63.1018
	Ascending colon + Healthy	60.5247
	Ascending colon	58.1357
	Large intestine	48.8995
	Ascending colon + Adenocarcinoma	47.3729
	Healthy	32.5508
	Large intestine + Healthy	6.8542

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A rapidly proliferating population of cells that differentiate from stem cells of the intestinal crypt of the colon. Stem cells located in the crypts of Lieberkühn give rise to proliferating progenitor or transit amplifying cells that differentiate into the four major epithelial cell types. These include columnar absorptive cells or enterocytes, mucous secreting goblet cells, enteroendocrine cells and paneth cells.

Synonyms: transit amplifying cell of large intestine, colon transit amplifying cell, transient amplifying cell of colon, transient amplifying cell of crypt of Lieberkuhn of colon, transit amplifying cell of crypt of Lieberkuhn of colon, transit-amplifying cell of colon