Cell ID: CL0009012

Cell Name: transit amplifying cell of small intestine

CSI Thresholds:

Select	Context	Threshold
	Overall	20.7441
	Ileum + Healthy	249.6793
	Ileum	245.0929
	Small intestine + Healthy	25.9452
	Healthy	21.9034
	Small intestine	16.3773
	Crohn ileitis	0.4268
	Ileum + Crohn ileitis	0.4247

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(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A rapidly proliferating population of cells that differentiate from stem cells of the intestinal crypt of the small intestine. Stem cells located in the crypts of Lieberkühn give rise to proliferating progenitor or transit amplifying cells that differentiate into the four major epithelial cell types. These include columnar absorptive cells or enterocytes, mucous secreting goblet cells, enteroendocrine cells and paneth cells.

Synonyms: small intestine transit amplifying cell, transient amplifying cell of crypt of Lieberkuhn of small intestine, transient amplifying cell of small intestine, transit amplifying cell of crypt of Lieberkuhn of small intestine, transit-amplifying cell of small intestine