Cell ID: CL1001106

Cell Name: kidney loop of Henle thick ascending limb epithelial cell

CSI Thresholds:

Select	Context	Threshold
	Overall	9.0118
	Type 2 diabetes mellitus	87.3616
	Cortex of kidney + Type 2 diabetes mellitus	77.0474
	Renal medulla + Acute kidney failure	60.6342
	Cortex of kidney + Acute kidney failure	60.1256
	Renal medulla + Chronic kidney disease	57.5188
	Kidney + Acute kidney failure	26.6555
	Kidney + Chronic kidney disease	21.9559
	Cortex of kidney + Chronic kidney disease	20.5971
	Acute kidney failure	20.4707
	Kidney + Healthy	20.0124
	Chronic kidney disease	12.5808
	Renal papilla + Healthy	12.2232
	Renal papilla	12.1662
	Nonpapillary renal cell carcinoma	10.6610
	Healthy	8.7289
	Renal medulla + Healthy	7.4757
	Kidney	7.0518
	Cortex of kidney + Healthy	5.6713
	Renal medulla	3.9592
	Cortex of kidney	3.8529
	Renal pelvis	2.6344
	Renal pelvis + Healthy	2.6320
	Kidney oncocytoma	0.6619
	Kidney + Kidney oncocytoma	0.6608
	Kidney + Nonpapillary renal cell carcinoma	0.0548

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(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: An epithelial cell that is part of some loop of Henle thick ascending limb. It is known in some mammalian species that this cell may express the Na+-K+-2Cl− cotransporter (NKCC2) apically.