Cell ID: CL4023011

Cell Name: lamp5 GABAergic cortical interneuron

CSI Thresholds:

Select	Context	Threshold
	Overall	21.6053
	Neocortex + Healthy	247.5951
	Neocortex	247.5760
	Middle temporal gyrus	197.2111
	Middle temporal gyrus + Dementia	142.3686
	Middle temporal gyrus + Healthy	119.3182
	Dementia	77.3345
	Dorsolateral prefrontal cortex + Dementia	40.5230
	Primary visual cortex	34.3452
	Prefrontal cortex	31.1530
	Telencephalon + Healthy	24.9041
	Entorhinal cortex	24.7529
	Entorhinal cortex + Healthy	24.7460
	Prefrontal cortex + Healthy	24.4345
	Dorsolateral prefrontal cortex + Healthy	22.6635
	Healthy	21.9522
	Frontal lobe	20.7303
	Frontal lobe + Isolated focal cortical dysplasia type II	20.6592
	Brodmann (1909) area 17	20.0044
	Dorsolateral prefrontal cortex	18.2663
	Brodmann (1909) area 17 + Healthy	17.0194
	Brodmann (1909) area 9	13.8569
	Brodmann (1909) area 10 + Healthy	13.2028
	Brodmann (1909) area 10	13.1810
	Isolated focal cortical dysplasia type II	11.5432
	Primary visual cortex + Healthy	9.7077
	Parietal lobe + Isolated focal cortical dysplasia type II	9.2111
	Parietal lobe	9.1693
	Primary auditory cortex	8.8274
	Primary auditory cortex + Healthy	8.7746
	Brodmann (1909) area 9 + Healthy	8.4926
	Primary somatosensory cortex + Healthy	6.9503
	Primary somatosensory cortex	6.7607
	Angular gyrus + Healthy	6.6980
	Angular gyrus	6.6235
	Anterior cingulate cortex + Healthy	5.2174
	Lobe of cerebral hemisphere	5.1828
	Lobe of cerebral hemisphere + Isolated focal cortical dysplasia type II	5.1570
	Anterior cingulate cortex	5.1397
	Visual cortex + Healthy	5.1136
	Visual cortex	5.1105
	Temporal lobe	4.3588
	Temporal lobe + Isolated focal cortical dysplasia type II	4.3522
	Ganglionic eminence	1.4398
	Ganglionic eminence + Healthy	0.7327
	Telencephalon	-1.0592

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(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses Lamp5. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters Lamp5.