Cell ID: CL4023016

Cell Name: VIP GABAergic cortical interneuron

CSI Thresholds:

Select	Context	Threshold
	Overall	20.0763
	Middle temporal gyrus	230.5638
	Middle temporal gyrus + Dementia	168.6747
	Neocortex + Healthy	112.0709
	Neocortex	111.7710
	Middle temporal gyrus + Healthy	92.3235
	Dorsolateral prefrontal cortex + Dementia	90.9069
	Dementia	60.0412
	Prefrontal cortex	40.3981
	Forebrain	40.0154
	Entorhinal cortex + Healthy	35.3891
	Entorhinal cortex	35.3832
	Primary visual cortex	34.1795
	Brodmann (1909) area 17	30.4198
	Prefrontal cortex + Healthy	30.0082
	Heart disorder	26.8463
	Medial orbital frontal cortex + Heart disorder	26.8034
	Dorsolateral prefrontal cortex	23.8867
	Dorsolateral prefrontal cortex + Healthy	23.2351
	Healthy	20.5722
	Brodmann (1909) area 9	19.7262
	Frontal lobe + Isolated focal cortical dysplasia type II	19.0587
	Frontal lobe	19.0003
	Breast cancer	18.2522
	Medial orbital frontal cortex + Breast cancer	18.2395
	Medial orbital frontal cortex + Influenza	17.8873
	Influenza	17.8728
	COVID-19	17.6587
	Medial orbital frontal cortex + COVID-19	17.6212
	Primary auditory cortex + Healthy	16.5788
	Primary auditory cortex	16.4707
	Brodmann (1909) area 17 + Healthy	15.6803
	Medial orbital frontal cortex	15.6277
	Medial orbital frontal cortex + Chronic obstructive pulmonary disease	15.3059
	Chronic obstructive pulmonary disease	15.2709
	Primary visual cortex + Healthy	14.5350
	Primary somatosensory cortex	14.5089
	Primary somatosensory cortex + Healthy	14.5021
	Myocardial infarction	14.4487
	Medial orbital frontal cortex + Myocardial infarction	14.4218
	Angular gyrus	14.1578
	Angular gyrus + Healthy	14.0143
	Brodmann (1909) area 10	11.6509
	Brodmann (1909) area 10 + Healthy	11.6486
	Anterior cingulate cortex	10.3792
	Anterior cingulate cortex + Healthy	10.3590
	Isolated focal cortical dysplasia type II	9.6645
	Parietal lobe	8.5376
	Parietal lobe + Isolated focal cortical dysplasia type II	8.5248
	Brodmann (1909) area 9 + Healthy	8.0194
	Small cell lung carcinoma	7.8253
	Medial orbital frontal cortex + Small cell lung carcinoma	7.8193
	Forebrain + Healthy	7.3205
	Ganglionic eminence + Healthy	6.5152
	Ganglionic eminence	6.2304
	Lobe of cerebral hemisphere + Isolated focal cortical dysplasia type II	4.9957
	Lobe of cerebral hemisphere	4.9905
	Visual cortex	4.6689
	Visual cortex + Healthy	4.6417
	Temporal lobe	4.4492
	Temporal lobe + Isolated focal cortical dysplasia type II	4.4489
	Medial orbital frontal cortex + Tongue cancer	4.2497
	Tongue cancer	4.2433
	Cardiomyopathy	0.8551
	Medial orbital frontal cortex + Cardiomyopathy	0.8526

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A transcriptomically distinct cortical GABAergic neuron that expresses the vasocactive intestinal polypeptide and that has its soma located in the cerebral cortex. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', cluster Vip.

Synonyms: VIP interneuron, VIP neuron, VIP-Expressing GABAergic Neuron, Vip GABAergic neuron, VIP type, VIP-IN, Vip, cortical VIP neuron