Cell ID: CL4023017

Cell Name: sst GABAergic cortical interneuron

CSI Thresholds:

Select	Context	Threshold
	Overall	19.7731
	Middle temporal gyrus	244.3685
	Neocortex	199.7701
	Neocortex + Healthy	199.7066
	Middle temporal gyrus + Dementia	180.6807
	Dementia	96.8350
	Dorsolateral prefrontal cortex + Dementia	94.1347
	Middle temporal gyrus + Healthy	92.8862
	Prefrontal cortex	48.7792
	Primary visual cortex	40.2146
	Entorhinal cortex + Healthy	31.0130
	Entorhinal cortex	30.9002
	Brodmann (1909) area 17	29.0292
	Forebrain	28.8913
	Prefrontal cortex + Healthy	28.0700
	Heart disorder	27.2433
	Medial orbital frontal cortex + Heart disorder	27.1959
	Brodmann (1909) area 9	24.0492
	Primary visual cortex + Healthy	23.3460
	Dorsolateral prefrontal cortex	22.6008
	Healthy	19.9778
	COVID-19	19.4216
	Medial orbital frontal cortex + COVID-19	19.4071
	Dorsolateral prefrontal cortex + Healthy	17.8713
	Frontal lobe + Isolated focal cortical dysplasia type II	17.7710
	Frontal lobe	17.7419
	Medial orbital frontal cortex + Breast cancer	17.3629
	Breast cancer	17.3539
	Influenza	17.0345
	Medial orbital frontal cortex + Influenza	17.0108
	Medial orbital frontal cortex	16.8493
	Chronic obstructive pulmonary disease	15.5857
	Medial orbital frontal cortex + Chronic obstructive pulmonary disease	15.5714
	Telencephalon + Healthy	14.0564
	Primary auditory cortex + Healthy	14.0313
	Primary auditory cortex	13.9257
	Primary somatosensory cortex	12.6494
	Primary somatosensory cortex + Healthy	12.6184
	Brodmann (1909) area 17 + Healthy	11.9153
	Angular gyrus + Healthy	11.6725
	Angular gyrus	11.6329
	Forebrain + Healthy	11.2300
	Brodmann (1909) area 10	10.2329
	Brodmann (1909) area 10 + Healthy	10.2302
	Telencephalon	10.2082
	Isolated focal cortical dysplasia type II	10.1997
	Medial orbital frontal cortex + Myocardial infarction	10.1217
	Myocardial infarction	10.1176
	Anterior cingulate cortex	8.9012
	Anterior cingulate cortex + Healthy	8.8838
	Brodmann (1909) area 9 + Healthy	8.1758
	Parietal lobe	7.8490
	Parietal lobe + Isolated focal cortical dysplasia type II	7.8293
	Ganglionic eminence	7.5750
	Ganglionic eminence + Healthy	7.5451
	Small cell lung carcinoma	5.9416
	Medial orbital frontal cortex + Small cell lung carcinoma	5.9070
	Lobe of cerebral hemisphere	4.5891
	Lobe of cerebral hemisphere + Isolated focal cortical dysplasia type II	4.5622
	Tongue cancer	4.0902
	Medial orbital frontal cortex + Tongue cancer	4.0864
	Temporal lobe	3.6651
	Temporal lobe + Isolated focal cortical dysplasia type II	3.6403
	Visual cortex + Healthy	3.6353
	Visual cortex	3.5974
	Cardiomyopathy	0.7107
	Medial orbital frontal cortex + Cardiomyopathy	0.7061

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses somatostatin (sst). The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: MGE-derived interneurons', Author Categories: 'CrossArea_subclass', cluster Sst.

Synonyms: SOM+ inhibitory interneuron, SST+ IN, somatostatin-expressing inhibitory interneuron