Cell ID: CL4023018

Cell Name: pvalb GABAergic cortical interneuron

CSI Thresholds:

Select	Context	Threshold
	Overall	21.2240
	Middle temporal gyrus	194.4571
	Middle temporal gyrus + Dementia	116.5141
	Neocortex	86.4107
	Neocortex + Healthy	85.5911
	Dorsolateral prefrontal cortex + Dementia	81.2977
	Dementia	76.7135
	Prefrontal cortex	56.7487
	Primary visual cortex	49.0046
	Middle temporal gyrus + Healthy	45.8911
	Entorhinal cortex + Healthy	36.4743
	Entorhinal cortex	36.3658
	Forebrain	35.2486
	Brodmann (1909) area 17	30.7718
	Dorsolateral prefrontal cortex	29.3665
	Prefrontal cortex + Healthy	29.0546
	Medial orbital frontal cortex + Heart disorder	26.8358
	Heart disorder	26.8266
	Brodmann (1909) area 9	25.1110
	Primary visual cortex + Healthy	24.2924
	Healthy	21.3777
	Medial orbital frontal cortex + Breast cancer	20.3447
	Breast cancer	20.2072
	Medial orbital frontal cortex + COVID-19	18.8295
	COVID-19	18.8115
	Dorsolateral prefrontal cortex + Healthy	18.5669
	Influenza	18.1987
	Medial orbital frontal cortex + Influenza	18.1893
	Brodmann (1909) area 17 + Healthy	17.6987
	Frontal lobe	17.5529
	Frontal lobe + Isolated focal cortical dysplasia type II	17.4499
	Medial orbital frontal cortex	16.2235
	Primary auditory cortex	16.0889
	Primary auditory cortex + Healthy	16.0306
	Myocardial infarction	15.5466
	Medial orbital frontal cortex + Myocardial infarction	15.5458
	Chronic obstructive pulmonary disease	15.5295
	Medial orbital frontal cortex + Chronic obstructive pulmonary disease	15.5047
	Primary somatosensory cortex	15.0688
	Primary somatosensory cortex + Healthy	15.0068
	Angular gyrus	14.1772
	Angular gyrus + Healthy	14.1259
	Telencephalon + Healthy	12.6146
	Brodmann (1909) area 10	11.8732
	Brodmann (1909) area 10 + Healthy	11.8584
	Anterior cingulate cortex + Healthy	10.4745
	Anterior cingulate cortex	10.4621
	Isolated focal cortical dysplasia type II	10.4230
	Brodmann (1909) area 9 + Healthy	9.3539
	Forebrain + Healthy	7.6944
	Parietal lobe	7.4370
	Parietal lobe + Isolated focal cortical dysplasia type II	7.4265
	Temporal lobe	6.7731
	Temporal lobe + Isolated focal cortical dysplasia type II	6.7700
	Medial orbital frontal cortex + Small cell lung carcinoma	6.5405
	Small cell lung carcinoma	6.5292
	Visual cortex + Healthy	5.6978
	Visual cortex	5.6762
	Medial orbital frontal cortex + Tongue cancer	4.5995
	Tongue cancer	4.5979
	Lobe of cerebral hemisphere	4.3565
	Lobe of cerebral hemisphere + Isolated focal cortical dysplasia type II	4.3288
	Telencephalon	4.3209
	Ganglionic eminence + Healthy	4.0711
	Ganglionic eminence	3.8386
	Medial orbital frontal cortex + Cardiomyopathy	0.4614
	Cardiomyopathy	0.4600

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A transcriptomically distinct GABAergic interneuron with a soma located in a cerebral cortex and it expresses Parvalbumin. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: MGE-derived interneurons', Author Categories: 'CrossArea_subclass', cluster Pvalb.