Cell ID: CL4023038

Cell Name: L6b glutamatergic cortical neuron

CSI Thresholds:

Select	Context	Threshold
	Overall	32.7400
	Middle temporal gyrus	223.1957
	Neocortex + Healthy	195.0635
	Neocortex	194.6449
	Middle temporal gyrus + Dementia	125.4807
	Middle temporal gyrus + Healthy	108.8869
	Dorsolateral prefrontal cortex + Dementia	98.3906
	Prefrontal cortex	58.6911
	Dementia	57.4628
	Primary visual cortex	47.0502
	Dorsolateral prefrontal cortex	36.7268
	Brodmann (1909) area 17	33.6228
	Healthy	33.4361
	Forebrain	29.5522
	Prefrontal cortex + Healthy	28.2245
	Brodmann (1909) area 9	27.6778
	Brodmann (1909) area 17 + Healthy	25.9154
	Dorsolateral prefrontal cortex + Healthy	23.7000
	Primary visual cortex + Healthy	23.1536
	Forebrain + Healthy	21.6964
	Telencephalon + Healthy	20.2414
	Telencephalon	16.4143
	Primary auditory cortex + Healthy	16.1536
	Primary auditory cortex	16.0835
	Primary somatosensory cortex + Healthy	15.1908
	Primary somatosensory cortex	15.1486
	Brodmann (1909) area 10 + Healthy	14.6844
	Brodmann (1909) area 10	14.6747
	Angular gyrus + Healthy	13.9022
	Angular gyrus	13.8653
	Anterior cingulate cortex	11.2615
	Anterior cingulate cortex + Healthy	11.1445
	Visual cortex	9.8549
	Visual cortex + Healthy	9.8506
	Brodmann (1909) area 9 + Healthy	9.6568

Select

(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: A glutamatergic neuron with a soma found in cortical layer 6b. They are transcriptomically related to corticothalamic-projecting neurons but have differential projections to the thalamus or anterior cingulate. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Deep layer (non-IT) excitatory neuron', Author Categories: 'CrossArea_subclass', cluster L6b.