Details for: CL4030006

Cell ID: CL4030006

Cell Name: fallopian tube secretory epithelial cell

Marker Score Threshold: 242,607
(Derived using integrated single-cell and genomic data)

Description: An epithelial cell that is part of the fallopian tube epithelium that secretes mucous fluid and oviduct-specific products through the stimulation of estrogen and luteinizing hormone. The fallopian tube secretory cell has approximately the same height as the ciliated cell and is usually a more narrow columnar cell. The nucleus is ovoid and perpendicular to the long axis of the cell. The chromatin is more dense and the nucleolus smaller than that seen in the ciliated cell.

Synonyms: oviduct secretory epithelial cell, uterine tube secretory epithelial cell

Genes (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Gene Symbol: ARG1 (ENSG00000118520)
    Fold Change: 1.04
    Ensembl ID: ENSG00000118520
  • Gene Symbol: CD1E (ENSG00000158488)
    Fold Change: 1.04
    Ensembl ID: ENSG00000158488
  • Gene Symbol: ADORA3 (ENSG00000282608)
    Fold Change: 1.04
    Ensembl ID: ENSG00000282608
  • Gene Symbol: AVPR1A (ENSG00000166148)
    Fold Change: 1.04
    Ensembl ID: ENSG00000166148
  • Gene Symbol: CD19 (ENSG00000177455)
    Fold Change: 1.04
    Ensembl ID: ENSG00000177455
  • Gene Symbol: AADAC (ENSG00000114771)
    Fold Change: 1.04
    Ensembl ID: ENSG00000114771
  • Gene Symbol: TNFRSF17 (ENSG00000048462)
    Fold Change: 1.04
    Ensembl ID: ENSG00000048462
  • Gene Symbol: SERPINA3 (ENSG00000196136)
    Fold Change: 1.04
    Ensembl ID: ENSG00000196136
  • Gene Symbol: ADRA2C (ENSG00000184160)
    Fold Change: 1.04
    Ensembl ID: ENSG00000184160
  • Gene Symbol: ALOX15 (ENSG00000161905)
    Fold Change: 1.04
    Ensembl ID: ENSG00000161905
  • Gene Symbol: BDKRB1 (ENSG00000100739)
    Fold Change: 1.04
    Ensembl ID: ENSG00000100739
  • Gene Symbol: BNC1 (ENSG00000169594)
    Fold Change: 1.04
    Ensembl ID: ENSG00000169594
  • Gene Symbol: CD40LG (ENSG00000102245)
    Fold Change: 1.04
    Ensembl ID: ENSG00000102245
  • Gene Symbol: CD1B (ENSG00000158485)
    Fold Change: 1.04
    Ensembl ID: ENSG00000158485
  • Gene Symbol: FASLG (ENSG00000117560)
    Fold Change: 1.04
    Ensembl ID: ENSG00000117560
  • Gene Symbol: CD33 (ENSG00000105383)
    Fold Change: 1.04
    Ensembl ID: ENSG00000105383
  • Gene Symbol: BLK (ENSG00000136573)
    Fold Change: 1.04
    Ensembl ID: ENSG00000136573
  • Gene Symbol: CALCB (ENSG00000175868)
    Fold Change: 1.04
    Ensembl ID: ENSG00000175868
  • Gene Symbol: AOX1 (ENSG00000138356)
    Fold Change: 1.04
    Ensembl ID: ENSG00000138356
  • Gene Symbol: CDH5 (ENSG00000179776)
    Fold Change: 1.04
    Ensembl ID: ENSG00000179776
  • Gene Symbol: CHGB (ENSG00000089199)
    Fold Change: 1.04
    Ensembl ID: ENSG00000089199
  • Gene Symbol: ALB (ENSG00000163631)
    Fold Change: 1.04
    Ensembl ID: ENSG00000163631
  • Gene Symbol: ADRA2A (ENSG00000150594)
    Fold Change: 1.04
    Ensembl ID: ENSG00000150594
  • Gene Symbol: CD28 (ENSG00000178562)
    Fold Change: 1.04
    Ensembl ID: ENSG00000178562
  • Gene Symbol: ASCL1 (ENSG00000139352)
    Fold Change: 1.04
    Ensembl ID: ENSG00000139352
  • Gene Symbol: CCNE1 (ENSG00000105173)
    Fold Change: 1.04
    Ensembl ID: ENSG00000105173
  • Gene Symbol: ACAN (ENSG00000157766)
    Fold Change: 1.04
    Ensembl ID: ENSG00000157766
  • Gene Symbol: CDC6 (ENSG00000094804)
    Fold Change: 1.04
    Ensembl ID: ENSG00000094804
  • Gene Symbol: CD22 (ENSG00000012124)
    Fold Change: 1.04
    Ensembl ID: ENSG00000012124
  • Gene Symbol: ADH1C (ENSG00000248144)
    Fold Change: 1.04
    Ensembl ID: ENSG00000248144
  • Gene Symbol: BUB1B (ENSG00000156970)
    Fold Change: 1.04
    Ensembl ID: ENSG00000156970
  • Gene Symbol: CD1D (ENSG00000158473)
    Fold Change: 1.04
    Ensembl ID: ENSG00000158473
  • Gene Symbol: MYRF (ENSG00000124920)
    Fold Change: 1.04
    Ensembl ID: ENSG00000124920
  • Gene Symbol: AQP9 (ENSG00000103569)
    Fold Change: 1.04
    Ensembl ID: ENSG00000103569
  • Gene Symbol: BMX (ENSG00000102010)
    Fold Change: 1.04
    Ensembl ID: ENSG00000102010
  • Gene Symbol: BMP3 (ENSG00000152785)
    Fold Change: 1.04
    Ensembl ID: ENSG00000152785
  • Gene Symbol: KIF1A (ENSG00000130294)
    Fold Change: 1.04
    Ensembl ID: ENSG00000130294
  • Gene Symbol: CFB (ENSG00000243649)
    Fold Change: 1.04
    Ensembl ID: ENSG00000243649
  • Gene Symbol: BMP4 (ENSG00000125378)
    Fold Change: 1.04
    Ensembl ID: ENSG00000125378
  • Gene Symbol: AGT (ENSG00000135744)
    Fold Change: 1.04
    Ensembl ID: ENSG00000135744
  • Gene Symbol: MPPED2 (ENSG00000066382)
    Fold Change: 1.04
    Ensembl ID: ENSG00000066382
  • Gene Symbol: C2 (ENSG00000166278)
    Fold Change: 1.04
    Ensembl ID: ENSG00000166278
  • Gene Symbol: CD79A (ENSG00000105369)
    Fold Change: 1.04
    Ensembl ID: ENSG00000105369
  • Gene Symbol: ACVRL1 (ENSG00000139567)
    Fold Change: 1.04
    Ensembl ID: ENSG00000139567
  • Gene Symbol: BTC (ENSG00000174808)
    Fold Change: 1.04
    Ensembl ID: ENSG00000174808
  • Gene Symbol: CEBPA (ENSG00000245848)
    Fold Change: 1.04
    Ensembl ID: ENSG00000245848
  • Gene Symbol: CD72 (ENSG00000137101)
    Fold Change: 1.04
    Ensembl ID: ENSG00000137101
  • Gene Symbol: CHEK1 (ENSG00000149554)
    Fold Change: 1.04
    Ensembl ID: ENSG00000149554
  • Gene Symbol: CA8 (ENSG00000178538)
    Fold Change: 1.04
    Ensembl ID: ENSG00000178538
  • Gene Symbol: ASGR1 (ENSG00000141505)
    Fold Change: 1.04
    Ensembl ID: ENSG00000141505
  • Gene Symbol: BIK (ENSG00000100290)
    Fold Change: 1.04
    Ensembl ID: ENSG00000100290
  • Gene Symbol: AR (ENSG00000169083)
    Fold Change: 1.04
    Ensembl ID: ENSG00000169083
  • Gene Symbol: BCHE (ENSG00000114200)
    Fold Change: 1.04
    Ensembl ID: ENSG00000114200
  • Gene Symbol: CD27 (ENSG00000139193)
    Fold Change: 1.04
    Ensembl ID: ENSG00000139193
  • Gene Symbol: CDS1 (ENSG00000163624)
    Fold Change: 1.04
    Ensembl ID: ENSG00000163624
  • Gene Symbol: BMP1 (ENSG00000168487)
    Fold Change: 1.04
    Ensembl ID: ENSG00000168487
  • Gene Symbol: CDH1 (ENSG00000039068)
    Fold Change: 1.04
    Ensembl ID: ENSG00000039068
  • Gene Symbol: ANXA3 (ENSG00000138772)
    Fold Change: 1.04
    Ensembl ID: ENSG00000138772
  • Gene Symbol: C5AR1 (ENSG00000197405)
    Fold Change: 1.04
    Ensembl ID: ENSG00000197405
  • Gene Symbol: ANGPT2 (ENSG00000091879)
    Fold Change: 1.04
    Ensembl ID: ENSG00000091879
  • Gene Symbol: AK4 (ENSG00000162433)
    Fold Change: 1.04
    Ensembl ID: ENSG00000162433
  • Gene Symbol: KLF5 (ENSG00000102554)
    Fold Change: 1.04
    Ensembl ID: ENSG00000102554
  • Gene Symbol: DDR1 (ENSG00000204580)
    Fold Change: 1.04
    Ensembl ID: ENSG00000204580
  • Gene Symbol: BRCA1 (ENSG00000012048)
    Fold Change: 1.04
    Ensembl ID: ENSG00000012048
  • Gene Symbol: BRCA2 (ENSG00000139618)
    Fold Change: 1.04
    Ensembl ID: ENSG00000139618
  • Gene Symbol: C3 (ENSG00000125730)
    Fold Change: 1.04
    Ensembl ID: ENSG00000125730
  • Gene Symbol: CD4 (ENSG00000010610)
    Fold Change: 1.04
    Ensembl ID: ENSG00000010610
  • Gene Symbol: CD79B (ENSG00000007312)
    Fold Change: 1.04
    Ensembl ID: ENSG00000007312
  • Gene Symbol: CHML (ENSG00000203668)
    Fold Change: 1.04
    Ensembl ID: ENSG00000203668
  • Gene Symbol: ALOX5 (ENSG00000012779)
    Fold Change: 1.04
    Ensembl ID: ENSG00000012779
  • Gene Symbol: CDH11 (ENSG00000140937)
    Fold Change: 1.04
    Ensembl ID: ENSG00000140937
  • Gene Symbol: C1R (ENSG00000159403)
    Fold Change: 1.04
    Ensembl ID: ENSG00000159403
  • Gene Symbol: AXL (ENSG00000167601)
    Fold Change: 1.04
    Ensembl ID: ENSG00000167601
  • Gene Symbol: ANK2 (ENSG00000145362)
    Fold Change: 1.04
    Ensembl ID: ENSG00000145362
  • Gene Symbol: CD36 (ENSG00000135218)
    Fold Change: 1.04
    Ensembl ID: ENSG00000135218
  • Gene Symbol: ASS1 (ENSG00000130707)
    Fold Change: 1.04
    Ensembl ID: ENSG00000130707
  • Gene Symbol: CDH13 (ENSG00000140945)
    Fold Change: 1.04
    Ensembl ID: ENSG00000140945
  • Gene Symbol: CD247 (ENSG00000198821)
    Fold Change: 1.04
    Ensembl ID: ENSG00000198821
  • Gene Symbol: ADAM8 (ENSG00000151651)
    Fold Change: 1.04
    Ensembl ID: ENSG00000151651
  • Gene Symbol: JAG1 (ENSG00000101384)
    Fold Change: 1.04
    Ensembl ID: ENSG00000101384
  • Gene Symbol: RUNX2 (ENSG00000124813)
    Fold Change: 1.04
    Ensembl ID: ENSG00000124813
  • Gene Symbol: ARL4D (ENSG00000175906)
    Fold Change: 1.04
    Ensembl ID: ENSG00000175906
  • Gene Symbol: CD68 (ENSG00000129226)
    Fold Change: 1.04
    Ensembl ID: ENSG00000129226
  • Gene Symbol: BCL7A (ENSG00000110987)
    Fold Change: 1.04
    Ensembl ID: ENSG00000110987
  • Gene Symbol: ENTPD1 (ENSG00000138185)
    Fold Change: 1.04
    Ensembl ID: ENSG00000138185
  • Gene Symbol: CD40 (ENSG00000101017)
    Fold Change: 1.04
    Ensembl ID: ENSG00000101017
  • Gene Symbol: ACP5 (ENSG00000102575)
    Fold Change: 1.04
    Ensembl ID: ENSG00000102575
  • Gene Symbol: PRDM1 (ENSG00000057657)
    Fold Change: 1.04
    Ensembl ID: ENSG00000057657
  • Gene Symbol: ABCA1 (ENSG00000165029)
    Fold Change: 1.04
    Ensembl ID: ENSG00000165029
  • Gene Symbol: CDC25B (ENSG00000101224)
    Fold Change: 1.04
    Ensembl ID: ENSG00000101224
  • Gene Symbol: RND3 (ENSG00000115963)
    Fold Change: 1.04
    Ensembl ID: ENSG00000115963
  • Gene Symbol: CETN2 (ENSG00000147400)
    Fold Change: 1.04
    Ensembl ID: ENSG00000147400
  • Gene Symbol: ABL2 (ENSG00000143322)
    Fold Change: 1.04
    Ensembl ID: ENSG00000143322
  • Gene Symbol: CALD1 (ENSG00000122786)
    Fold Change: 1.04
    Ensembl ID: ENSG00000122786
  • Gene Symbol: AHCY (ENSG00000101444)
    Fold Change: 1.04
    Ensembl ID: ENSG00000101444
  • Gene Symbol: SLC25A4 (ENSG00000151729)
    Fold Change: 1.04
    Ensembl ID: ENSG00000151729
  • Gene Symbol: AP1B1 (ENSG00000100280)
    Fold Change: 1.04
    Ensembl ID: ENSG00000100280
  • Gene Symbol: ATP6V1B2 (ENSG00000147416)
    Fold Change: 1.04
    Ensembl ID: ENSG00000147416
  • Gene Symbol: CD74 (ENSG00000019582)
    Fold Change: 1.04
    Ensembl ID: ENSG00000019582
  • Gene Symbol: ACTB (ENSG00000075624)
    Fold Change: 1.03
    Ensembl ID: ENSG00000075624

Gene ID: A unique numerical identifier for this specific gene.
Symbol: Shortened abbreviation or name that represents this gene.
Ensembl Gene ID: A unique identifier assigned by Ensembl for genomic data mapping.
Fold Change: Indicates the ratio of the gene's expression level in fallopian tube secretory epithelial cell cell compared to a baseline. A fold change greater than 1 suggests significant gene expression.

Gene ID: A unique numerical identifier for this specific gene.
Symbol: Shortened abbreviation or name that represents this gene.
Ensembl Gene ID: A unique identifier assigned by Ensembl for genomic data mapping.
Fold Change: Indicates the ratio of the gene's expression level in fallopian tube secretory epithelial cell cell compared to a baseline. A fold change greater than 1 suggests significant gene expression.
**Key Characteristics** * Narrow columnar shape * Ovoid nucleus perpendicular to the long axis of the cell * Chromatin is more dense and the nucleolus is smaller than in ciliated cells * Secretes mucous fluid and oviduct-specific products in response to estrogen and luteinizing hormone stimulation * Involved in adaptive immune response, antigen processing and presentation, and regulation of heart contraction * Gene symbols: ARG1, CD1E, ADORA3, AVPR1A, CD19, AADAC, TNFRSF17, SERPINA3, ADRA2C * Ensembl IDs: ENSG00000118520, ENSG00000158488, ENSG00000282608, ENSG00000166148, ENSG00000177455, ENSG00000114771, ENSG00000048462, ENSG00000196136, ENSG00000184160 **Clinical Significance** Fallopian tube secretory epithelial cells play a crucial role in maintaining reproductive health. Abnormalities in FTSEC function or expression have been implicated in various reproductive disorders, including infertility, endometriosis, and ovulatory dysfunction. The identification of FTSEC-specific genes and their involvement in various cellular processes has implications for the development of novel therapeutic strategies for these disorders. Some of the clinical significance of FTSECs includes: * Regulation of ovulation and fertility: FTSECs play a crucial role in the regulation of ovulation and fertility, and abnormalities in FTSEC function or expression have been implicated in infertility. * Endometriosis: FTSECs have been shown to play a role in the development and progression of endometriosis, a common gynecological disorder characterized by the growth of endometrial tissue outside the uterus. * Ovulatory dysfunction: FTSECs have been implicated in ovulatory dysfunction, which is a common cause of infertility. * Reproductive cancer: FTSECs have been shown to play a role in the development and progression of reproductive cancers, such as endometrial cancer. Overall, the study of FTSECs has significant implications for our understanding of reproductive health and the development of novel therapeutic strategies for reproductive disorders.