Details for: CDH2

Gene ID: 1000

Symbol: CDH2

Ensembl ID: ENSG00000170558

Description: cadherin 2

Associated with

Other Information

Genular Protein ID: 1163920042

Symbol: CADH2_HUMAN

Name: Cadherin-2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2216790

Title: Human N-cadherin: nucleotide and deduced amino acid sequence.

PubMed ID: 2216790

DOI: 10.1093/nar/18.19.5896

PubMed ID: 1500442

Title: Extrajunctional distribution of N-cadherin in cultured human endothelial cells.

PubMed ID: 1500442

DOI: 10.1242/jcs.102.1.7

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2384753

Title: N-cadherin gene maps to human chromosome 18 and is not linked to the E-cadherin gene.

PubMed ID: 2384753

DOI: 10.1111/j.1471-4159.1990.tb04563.x

PubMed ID: 7959764

Title: Structure of the human N-cadherin gene: YAC analysis and fine chromosomal mapping to 18q11.2.

PubMed ID: 7959764

DOI: 10.1006/geno.1994.1358

PubMed ID: 16007225

Title: Adhesion signaling by a novel mitotic substrate of src kinases.

PubMed ID: 16007225

DOI: 10.1038/sj.onc.1208582

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

PubMed ID: 28169360

Title: Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway.

PubMed ID: 28169360

DOI: 10.1038/srep42125

PubMed ID: 32341084

Title: Fbxo45 Binds SPRY Motifs in the Extracellular Domain of N-Cadherin and Regulates Neuron Migration during Brain Development.

PubMed ID: 32341084

DOI: 10.1128/mcb.00539-19

PubMed ID: 28280076

Title: Identification of cadherin 2 (CDH2) mutations in arrhythmogenic right ventricular cardiomyopathy.

PubMed ID: 28280076

DOI: 10.1161/circgenetics.116.001605

PubMed ID: 28326674

Title: Whole exome sequencing with genomic triangulation implicates CDH2-encoded N-cadherin as a novel pathogenic substrate for arrhythmogenic cardiomyopathy.

PubMed ID: 28326674

DOI: 10.1111/chd.12462

PubMed ID: 31585109

Title: De novo pathogenic variants in N-cadherin cause a syndromic neurodevelopmental disorder with corpus collosum, axon, cardiac, ocular, and genital defects.

PubMed ID: 31585109

DOI: 10.1016/j.ajhg.2019.09.005

PubMed ID: 31650526

Title: Novel variants in CDH2 are associated with a new syndrome including Peters anomaly.

PubMed ID: 31650526

DOI: 10.1111/cge.13660

PubMed ID: 34702855

Title: CDH2 mutation affecting N-cadherin function causes attention-deficit hyperactivity disorder in humans and mice.

PubMed ID: 34702855

DOI: 10.1038/s41467-021-26426-1

Sequence Information:

  • Length: 906
  • Mass: 99809
  • Checksum: 7267E2A00489DF94
  • Sequence:
  • MCRIAGALRT LLPLLAALLQ ASVEASGEIA LCKTGFPEDV YSAVLSKDVH EGQPLLNVKF 
    SNCNGKRKVQ YESSEPADFK VDEDGMVYAV RSFPLSSEHA KFLIYAQDKE TQEKWQVAVK 
    LSLKPTLTEE SVKESAEVEE IVFPRQFSKH SGHLQRQKRD WVIPPINLPE NSRGPFPQEL 
    VRIRSDRDKN LSLRYSVTGP GADQPPTGIF IINPISGQLS VTKPLDREQI ARFHLRAHAV 
    DINGNQVENP IDIVINVIDM NDNRPEFLHQ VWNGTVPEGS KPGTYVMTVT AIDADDPNAL 
    NGMLRYRIVS QAPSTPSPNM FTINNETGDI ITVAAGLDRE KVQQYTLIIQ ATDMEGNPTY 
    GLSNTATAVI TVTDVNDNPP EFTAMTFYGE VPENRVDIIV ANLTVTDKDQ PHTPAWNAVY 
    RISGGDPTGR FAIQTDPNSN DGLVTVVKPI DFETNRMFVL TVAAENQVPL AKGIQHPPQS 
    TATVSVTVID VNENPYFAPN PKIIRQEEGL HAGTMLTTFT AQDPDRYMQQ NIRYTKLSDP 
    ANWLKIDPVN GQITTIAVLD RESPNVKNNI YNATFLASDN GIPPMSGTGT LQIYLLDIND 
    NAPQVLPQEA ETCETPDPNS INITALDYDI DPNAGPFAFD LPLSPVTIKR NWTITRLNGD 
    FAQLNLKIKF LEAGIYEVPI IITDSGNPPK SNISILRVKV CQCDSNGDCT DVDRIVGAGL 
    GTGAIIAILL CIIILLILVL MFVVWMKRRD KERQAKQLLI DPEDDVRDNI LKYDEEGGGE 
    EDQDYDLSQL QQPDTVEPDA IKPVGIRRMD ERPIHAEPQY PVRSAAPHPG DIGDFINEGL 
    KAADNDPTAP PYDSLLVFDY EGSGSTAGSL SSLNSSSSGG EQDYDYLNDW GPRFKKLADM 
    YGGGDD

Genular Protein ID: 407073305

Symbol: C9J126_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

Sequence Information:

  • Length: 821
  • Mass: 90673
  • Checksum: 3E288C4557CA8D30
  • Sequence:
  • MVYAVRSFPL SSEHAKFLIY AQDKETQEKW QVAVKLSLKP TLTEESVKES AEVEEIVFPR 
    QFSKHSGHLQ RQKRDWVIPP INLPENSRGP FPQELVRIRS DRDKNLSLRY SVTGPGADQP 
    PTGIFIINPI SGQLSVTKPL DREQIARFHL RAHAVDINGN QVENPIDIVI NVIDMNDNRP 
    EFLHQVWNGT VPEGSKPGTY VMTVTAIDAD DPNALNGMLR YRIVSQAPST PSPNMFTINN 
    ETGDIITVAA GLDREKVQQY TLIIQATDME GNPTYGLSNT ATAVITVTDV NDNPPEFTAM 
    TFYGEVPENR VDIIVANLTV TDKDQPHTPA WNAVYRISGG DPTGRFAIQT DPNSNDGLVT 
    VVKPIDFETN RMFVLTVAAE NQVPLAKGIQ HPPQSTATVS VTVIDVNENP YFAPNPKIIR 
    QEEGLHAGTM LTTFTAQDPD RYMQQNIRYT KLSDPANWLK IDPVNGQITT IAVLDRESPN 
    VKNNIYNATF LASDNGIPPM SGTGTLQIYL LDINDNAPQV LPQEAETCET PDPNSINITA 
    LDYDIDPNAG PFAFDLPLSP VTIKRNWTIT RLNGDFAQLN LKIKFLEAGI YEVPIIITDS 
    GNPPKSNISI LRVKVCQCDS NGDCTDVDRI VGAGLGTGAI IAILLCIIIL LILVLMFVVW 
    MKRRDKERQA KQLLIDPEDD VRDNILKYDE EGGGEEDQDY DLSQLQQPDT VEPDAIKPVG 
    IRRMDERPIH AEPQYPVRSA APHPGDIGDF INEGLKAADN DPTAPPYDSL LVFDYEGSGS 
    TAGSLSSLNS SSSGGEQDYD YLNDWGPRFK KLADMYGGGD D

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.