Details for: CDH2

Gene ID: 1000

Symbol: CDH2

Ensembl ID: ENSG00000170558

Description: cadherin 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 377.6956
    Cell Significance Index: -95.8000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 197.5652
    Cell Significance Index: -93.2800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 24.6677
    Cell Significance Index: -97.3400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 9.6367
    Cell Significance Index: 540.7600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 6.9841
    Cell Significance Index: 535.9500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 3.3510
    Cell Significance Index: 205.9700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 3.1246
    Cell Significance Index: 46.1300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.8414
    Cell Significance Index: 569.9900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 2.5581
    Cell Significance Index: 61.3500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 2.4526
    Cell Significance Index: 154.5800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 2.1859
    Cell Significance Index: 317.7500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.9938
    Cell Significance Index: 395.6700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.7984
    Cell Significance Index: 645.0500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.7121
    Cell Significance Index: 115.1200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.2548
    Cell Significance Index: 867.8500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.0354
    Cell Significance Index: 1593.9800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.8545
    Cell Significance Index: 1575.9400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.8264
    Cell Significance Index: 524.8800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.5937
    Cell Significance Index: 7.0800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.5684
    Cell Significance Index: 772.8700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5594
    Cell Significance Index: 305.4800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.4505
    Cell Significance Index: 7.7200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.3920
    Cell Significance Index: 738.1600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.3724
    Cell Significance Index: 16.4700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.1318
    Cell Significance Index: 3.7600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0697
    Cell Significance Index: 2.6400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.1173
    Cell Significance Index: -51.8600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.1224
    Cell Significance Index: -89.7300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.1286
    Cell Significance Index: -95.3000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.1431
    Cell Significance Index: -108.3000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1813
    Cell Significance Index: -82.2800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1841
    Cell Significance Index: -103.8500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1989
    Cell Significance Index: -124.2000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.2649
    Cell Significance Index: -36.3800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2899
    Cell Significance Index: -83.4000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3088
    Cell Significance Index: -10.7300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.3731
    Cell Significance Index: -67.2500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3774
    Cell Significance Index: -9.9300
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.3809
    Cell Significance Index: -5.8000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.4058
    Cell Significance Index: -52.0200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.5684
    Cell Significance Index: -119.7300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.5730
    Cell Significance Index: -70.4500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.7135
    Cell Significance Index: -92.1800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.7182
    Cell Significance Index: -122.6400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.7738
    Cell Significance Index: -15.3000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.7766
    Cell Significance Index: -79.3300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.7801
    Cell Significance Index: -13.1400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.7805
    Cell Significance Index: -55.2000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.8031
    Cell Significance Index: -93.5900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.8109
    Cell Significance Index: -95.6300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.8234
    Cell Significance Index: -85.7400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.8640
    Cell Significance Index: -23.1500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.9400
    Cell Significance Index: -26.2700
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.9421
    Cell Significance Index: -12.0800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -1.0022
    Cell Significance Index: -114.8200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.0061
    Cell Significance Index: -32.9400
  • Cell Name: neural cell (CL0002319)
    Fold Change: -1.0115
    Cell Significance Index: -11.8000
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -1.0825
    Cell Significance Index: -7.8700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -1.1002
    Cell Significance Index: -24.0900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.1027
    Cell Significance Index: -35.1200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.1294
    Cell Significance Index: -89.4500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.1876
    Cell Significance Index: -34.9800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -1.1990
    Cell Significance Index: -89.3600
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -1.2578
    Cell Significance Index: -19.4600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -1.3621
    Cell Significance Index: -14.8400
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -1.4307
    Cell Significance Index: -17.7500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.5192
    Cell Significance Index: -79.7700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -1.5573
    Cell Significance Index: -81.1200
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -1.5840
    Cell Significance Index: -23.3800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.6464
    Cell Significance Index: -42.3200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.6489
    Cell Significance Index: -101.0900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -1.6912
    Cell Significance Index: -35.4000
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -1.8825
    Cell Significance Index: -59.5400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -1.8885
    Cell Significance Index: -37.9200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -1.9488
    Cell Significance Index: -91.5900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.9733
    Cell Significance Index: -69.1300
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -1.9843
    Cell Significance Index: -20.6700
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -2.0162
    Cell Significance Index: -34.8600
  • Cell Name: neuron (CL0000540)
    Fold Change: -2.0477
    Cell Significance Index: -19.4100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -2.1598
    Cell Significance Index: -45.8400
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -2.1912
    Cell Significance Index: -29.2300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -2.2387
    Cell Significance Index: -32.0600
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -2.3542
    Cell Significance Index: -32.9200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -2.3933
    Cell Significance Index: -111.5900
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -2.3937
    Cell Significance Index: -33.5800
  • Cell Name: glioblast (CL0000030)
    Fold Change: -2.4635
    Cell Significance Index: -15.4700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -2.5646
    Cell Significance Index: -55.4100
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -2.6113
    Cell Significance Index: -20.0900
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -2.6406
    Cell Significance Index: -15.6700
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -2.6769
    Cell Significance Index: -55.8700
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -2.7152
    Cell Significance Index: -67.7300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -2.7432
    Cell Significance Index: -100.7000
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -2.7672
    Cell Significance Index: -67.0300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -3.0496
    Cell Significance Index: -107.1600
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -3.1604
    Cell Significance Index: -31.2700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -3.1634
    Cell Significance Index: -90.6800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -3.2606
    Cell Significance Index: -95.7600
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -3.2833
    Cell Significance Index: -37.5800
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -3.2879
    Cell Significance Index: -41.4900
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -3.2923
    Cell Significance Index: -46.2400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Cell-cell adhesion**: CDH2 is a transmembrane protein that mediates calcium-dependent cell-cell adhesion via its extracellular domain, which interacts with the cytoplasmic domain of β-catenin and actin filaments. 2. **Cell junction formation**: CDH2 forms adherens junctions with other cells, which are composed of the cytoplasmic domain of CDH2, β-catenin, and actin filaments. 3. **Tissue morphogenesis**: CDH2 plays a crucial role in tissue morphogenesis, including the development of the cerebral cortex, brain, and cardiovascular system. 4. **Regulation of cellular processes**: CDH2 regulates various cellular processes, including cell migration, proliferation, and differentiation, through its interaction with other proteins and signaling pathways. **Pathways and Functions** 1. **Adherens junction organization**: CDH2 is essential for the formation and maintenance of adherens junctions, which are critical for maintaining tissue structure and function. 2. **Apical-basal polarity**: CDH2 helps establish apical-basal polarity in epithelial cells, which is essential for maintaining tissue structure and function. 3. **Calcium-dependent signaling**: CDH2 mediates calcium-dependent signaling pathways, which are involved in various cellular processes, including cell migration and proliferation. 4. **Wnt signaling pathway regulation**: CDH2 negatively regulates the canonical Wnt signaling pathway, which is involved in various cellular processes, including cell proliferation and differentiation. **Clinical Significance** 1. **Cancer**: CDH2 is frequently downregulated in various types of cancer, including breast, lung, and colon cancer, which is associated with a poor prognosis. 2. **Cardiovascular disease**: CDH2 is involved in the development of cardiovascular disease, including atherosclerosis and cardiac arrhythmias. 3. **Neurological disorders**: CDH2 is implicated in various neurological disorders, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis. 4. **Regenerative medicine**: CDH2 is being explored as a potential target for regenerative medicine, including tissue engineering and stem cell therapy. In conclusion, CDH2 is a critical protein that plays a significant role in maintaining tissue integrity and regulating various cellular processes. Alterations in CDH2 expression have been implicated in various diseases, and its dysregulation has significant clinical implications. Further research is needed to fully understand the mechanisms by which CDH2 regulates cellular processes and to develop therapeutic strategies to target CDH2 in disease prevention and treatment.

Genular Protein ID: 1163920042

Symbol: CADH2_HUMAN

Name: Cadherin-2

UniProtKB Accession Codes:

P19022 A8MWK3 B0YIY6 Q14923 Q8N173

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CPTAC 7 CPTC 1 CTD 1 ChEBI 15 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 Ensembl 2 ExpressionAtlas 1 GO 65 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 7 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 4 RefSeq 2 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2216790

Title: Human N-cadherin: nucleotide and deduced amino acid sequence.

PubMed ID: 2216790

DOI: 10.1093/nar/18.19.5896

PubMed ID: 1500442

Title: Extrajunctional distribution of N-cadherin in cultured human endothelial cells.

PubMed ID: 1500442

DOI: 10.1242/jcs.102.1.7

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2384753

Title: N-cadherin gene maps to human chromosome 18 and is not linked to the E-cadherin gene.

PubMed ID: 2384753

DOI: 10.1111/j.1471-4159.1990.tb04563.x

PubMed ID: 7959764

Title: Structure of the human N-cadherin gene: YAC analysis and fine chromosomal mapping to 18q11.2.

PubMed ID: 7959764

DOI: 10.1006/geno.1994.1358

PubMed ID: 16007225

Title: Adhesion signaling by a novel mitotic substrate of src kinases.

PubMed ID: 16007225

DOI: 10.1038/sj.onc.1208582

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

PubMed ID: 28169360

Title: Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway.

PubMed ID: 28169360

DOI: 10.1038/srep42125

PubMed ID: 32341084

Title: Fbxo45 Binds SPRY Motifs in the Extracellular Domain of N-Cadherin and Regulates Neuron Migration during Brain Development.

PubMed ID: 32341084

DOI: 10.1128/mcb.00539-19

PubMed ID: 28280076

Title: Identification of cadherin 2 (CDH2) mutations in arrhythmogenic right ventricular cardiomyopathy.

PubMed ID: 28280076

DOI: 10.1161/circgenetics.116.001605

PubMed ID: 28326674

Title: Whole exome sequencing with genomic triangulation implicates CDH2-encoded N-cadherin as a novel pathogenic substrate for arrhythmogenic cardiomyopathy.

PubMed ID: 28326674

DOI: 10.1111/chd.12462

PubMed ID: 31585109

Title: De novo pathogenic variants in N-cadherin cause a syndromic neurodevelopmental disorder with corpus collosum, axon, cardiac, ocular, and genital defects.

PubMed ID: 31585109

DOI: 10.1016/j.ajhg.2019.09.005

PubMed ID: 31650526

Title: Novel variants in CDH2 are associated with a new syndrome including Peters anomaly.

PubMed ID: 31650526

DOI: 10.1111/cge.13660

PubMed ID: 34702855

Title: CDH2 mutation affecting N-cadherin function causes attention-deficit hyperactivity disorder in humans and mice.

PubMed ID: 34702855

DOI: 10.1038/s41467-021-26426-1

Sequence Information:

  • Length: 906
  • Mass: 99809
  • Checksum: 7267E2A00489DF94
  • Sequence:
    • MCRIAGALRT LLPLLAALLQ ASVEASGEIA LCKTGFPEDV YSAVLSKDVH EGQPLLNVKF 
SNCNGKRKVQ YESSEPADFK VDEDGMVYAV RSFPLSSEHA KFLIYAQDKE TQEKWQVAVK 
LSLKPTLTEE SVKESAEVEE IVFPRQFSKH SGHLQRQKRD WVIPPINLPE NSRGPFPQEL 
VRIRSDRDKN LSLRYSVTGP GADQPPTGIF IINPISGQLS VTKPLDREQI ARFHLRAHAV 
DINGNQVENP IDIVINVIDM NDNRPEFLHQ VWNGTVPEGS KPGTYVMTVT AIDADDPNAL 
NGMLRYRIVS QAPSTPSPNM FTINNETGDI ITVAAGLDRE KVQQYTLIIQ ATDMEGNPTY 
GLSNTATAVI TVTDVNDNPP EFTAMTFYGE VPENRVDIIV ANLTVTDKDQ PHTPAWNAVY 
RISGGDPTGR FAIQTDPNSN DGLVTVVKPI DFETNRMFVL TVAAENQVPL AKGIQHPPQS 
TATVSVTVID VNENPYFAPN PKIIRQEEGL HAGTMLTTFT AQDPDRYMQQ NIRYTKLSDP 
ANWLKIDPVN GQITTIAVLD RESPNVKNNI YNATFLASDN GIPPMSGTGT LQIYLLDIND 
NAPQVLPQEA ETCETPDPNS INITALDYDI DPNAGPFAFD LPLSPVTIKR NWTITRLNGD 
FAQLNLKIKF LEAGIYEVPI IITDSGNPPK SNISILRVKV CQCDSNGDCT DVDRIVGAGL 
GTGAIIAILL CIIILLILVL MFVVWMKRRD KERQAKQLLI DPEDDVRDNI LKYDEEGGGE 
EDQDYDLSQL QQPDTVEPDA IKPVGIRRMD ERPIHAEPQY PVRSAAPHPG DIGDFINEGL 
KAADNDPTAP PYDSLLVFDY EGSGSTAGSL SSLNSSSSGG EQDYDYLNDW GPRFKKLADM 
YGGGDD

Genular Protein ID: 407073305

Symbol: C9J126_HUMAN

Name: N/A

UniProtKB Accession Codes:

C9J126

Database IDs:

ARBA 14 Antibodypedia 1 Bgee 1 CDD 1 CTD 1 ChiTaRS 1 DisGeNET 1 EMBL 3 Ensembl 3 GO 5 Gene3D 2 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 2 SAM 2 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

Sequence Information:

  • Length: 821
  • Mass: 90673
  • Checksum: 3E288C4557CA8D30
  • Sequence:
    • MVYAVRSFPL SSEHAKFLIY AQDKETQEKW QVAVKLSLKP TLTEESVKES AEVEEIVFPR 
QFSKHSGHLQ RQKRDWVIPP INLPENSRGP FPQELVRIRS DRDKNLSLRY SVTGPGADQP 
PTGIFIINPI SGQLSVTKPL DREQIARFHL RAHAVDINGN QVENPIDIVI NVIDMNDNRP 
EFLHQVWNGT VPEGSKPGTY VMTVTAIDAD DPNALNGMLR YRIVSQAPST PSPNMFTINN 
ETGDIITVAA GLDREKVQQY TLIIQATDME GNPTYGLSNT ATAVITVTDV NDNPPEFTAM 
TFYGEVPENR VDIIVANLTV TDKDQPHTPA WNAVYRISGG DPTGRFAIQT DPNSNDGLVT 
VVKPIDFETN RMFVLTVAAE NQVPLAKGIQ HPPQSTATVS VTVIDVNENP YFAPNPKIIR 
QEEGLHAGTM LTTFTAQDPD RYMQQNIRYT KLSDPANWLK IDPVNGQITT IAVLDRESPN 
VKNNIYNATF LASDNGIPPM SGTGTLQIYL LDINDNAPQV LPQEAETCET PDPNSINITA 
LDYDIDPNAG PFAFDLPLSP VTIKRNWTIT RLNGDFAQLN LKIKFLEAGI YEVPIIITDS 
GNPPKSNISI LRVKVCQCDS NGDCTDVDRI VGAGLGTGAI IAILLCIIIL LILVLMFVVW 
MKRRDKERQA KQLLIDPEDD VRDNILKYDE EGGGEEDQDY DLSQLQQPDT VEPDAIKPVG 
IRRMDERPIH AEPQYPVRSA APHPGDIGDF INEGLKAADN DPTAPPYDSL LVFDYEGSGS 
TAGSLSSLNS SSSGGEQDYD YLNDWGPRFK KLADMYGGGD D

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.