Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: photoreceptor cell (CL0000210)
Fold Change: 5.99
Marker Score: 4,506 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 4.96
Marker Score: 110,819 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 4.75
Marker Score: 24,893 - Cell Name: stellate neuron (CL0000122)
Fold Change: 4.45
Marker Score: 23,910 - Cell Name: granule cell (CL0000120)
Fold Change: 4.06
Marker Score: 30,627 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 3.92
Marker Score: 13,142 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 3.86
Marker Score: 5,186 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 3.67
Marker Score: 4,441 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 3.36
Marker Score: 14,015 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 3.33
Marker Score: 112,558 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 3.29
Marker Score: 58,340 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 3.26
Marker Score: 11,587 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 2.96
Marker Score: 4,162 - Cell Name: macroglial cell (CL0000126)
Fold Change: 2.94
Marker Score: 6,750 - Cell Name: Mueller cell (CL0000636)
Fold Change: 2.87
Marker Score: 3,982 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 2.78
Marker Score: 1,556 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.75
Marker Score: 58,659 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.68
Marker Score: 1,565 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 2.66
Marker Score: 1,552 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.65
Marker Score: 52,768 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.65
Marker Score: 773 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 2.52
Marker Score: 1,463 - Cell Name: hepatoblast (CL0005026)
Fold Change: 2.45
Marker Score: 8,011 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 2.33
Marker Score: 2,900 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 2.31
Marker Score: 1,111 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.29
Marker Score: 881 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.27
Marker Score: 86,329 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 2.26
Marker Score: 9,471 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.15
Marker Score: 9,944 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 2.13
Marker Score: 6,066 - Cell Name: sympathetic neuron (CL0011103)
Fold Change: 2.1
Marker Score: 694 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.1
Marker Score: 31,370 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 2.08
Marker Score: 1,243 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 2.06
Marker Score: 1,358 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.03
Marker Score: 8,435 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.01
Marker Score: 123,568 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.97
Marker Score: 15,124 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.91
Marker Score: 18,152 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.89
Marker Score: 69,706 - Cell Name: preosteoblast (CL0007010)
Fold Change: 1.88
Marker Score: 532 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 1.88
Marker Score: 3,919 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.87
Marker Score: 7,223 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.86
Marker Score: 15,999 - Cell Name: ganglion interneuron (CL0000397)
Fold Change: 1.81
Marker Score: 548 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 1.78
Marker Score: 10,560 - Cell Name: neuron (CL0000540)
Fold Change: 1.77
Marker Score: 7,194 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.76
Marker Score: 16,551 - Cell Name: inhibitory motor neuron (CL0008015)
Fold Change: 1.76
Marker Score: 829 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 1.72
Marker Score: 1,927 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 1.7
Marker Score: 22,642 - Cell Name: neural crest cell (CL0011012)
Fold Change: 1.65
Marker Score: 1,763 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1.65
Marker Score: 2,035 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 1.64
Marker Score: 2,046 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.62
Marker Score: 16,759 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.61
Marker Score: 481 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.6
Marker Score: 2,690 - Cell Name: osteoblast (CL0000062)
Fold Change: 1.59
Marker Score: 853 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.59
Marker Score: 1,374 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 1.59
Marker Score: 3,795 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.58
Marker Score: 3,714 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 1.57
Marker Score: 9,430 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.55
Marker Score: 2,397 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 1.53
Marker Score: 1,442 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 1.51
Marker Score: 5,863 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 1.48
Marker Score: 5,248 - Cell Name: kidney cell (CL1000497)
Fold Change: 1.47
Marker Score: 984 - Cell Name: mural cell (CL0008034)
Fold Change: 1.46
Marker Score: 167,447 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.45
Marker Score: 9,342 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.44
Marker Score: 1,555 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.4
Marker Score: 6,059 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 1.4
Marker Score: 881 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1.39
Marker Score: 503 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.36
Marker Score: 865 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.36
Marker Score: 21,213 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 1.35
Marker Score: 7,256 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 1.33
Marker Score: 448 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.3
Marker Score: 546 - Cell Name: glial cell (CL0000125)
Fold Change: 1.29
Marker Score: 1,416 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.25
Marker Score: 2,537 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 1.24
Marker Score: 650 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 1.22
Marker Score: 2,067 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.21
Marker Score: 12,131 - Cell Name: bipolar neuron (CL0000103)
Fold Change: 1.2
Marker Score: 405 - Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.19
Marker Score: 1,488 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.18
Marker Score: 444 - Cell Name: motor neuron (CL0000100)
Fold Change: 1.18
Marker Score: 698 - Cell Name: fetal cardiomyocyte (CL0002495)
Fold Change: 1.16
Marker Score: 382 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.16
Marker Score: 694 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.14
Marker Score: 388 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.14
Marker Score: 311 - Cell Name: neural cell (CL0002319)
Fold Change: 1.13
Marker Score: 545 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 1.09
Marker Score: 350 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 1.09
Marker Score: 3,101 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.07
Marker Score: 36,900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 1.04
Marker Score: 433 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 1.02
Marker Score: 2,403 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,789 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 1
Marker Score: 1,055 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,014 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,406
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1163920042
Symbol: CADH2_HUMAN
Name: Cadherin-2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2216790
Title: Human N-cadherin: nucleotide and deduced amino acid sequence.
PubMed ID: 2216790
PubMed ID: 1500442
Title: Extrajunctional distribution of N-cadherin in cultured human endothelial cells.
PubMed ID: 1500442
DOI: 10.1242/jcs.102.1.7
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16177791
Title: DNA sequence and analysis of human chromosome 18.
PubMed ID: 16177791
DOI: 10.1038/nature03983
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2384753
Title: N-cadherin gene maps to human chromosome 18 and is not linked to the E-cadherin gene.
PubMed ID: 2384753
PubMed ID: 7959764
Title: Structure of the human N-cadherin gene: YAC analysis and fine chromosomal mapping to 18q11.2.
PubMed ID: 7959764
PubMed ID: 16007225
Title: Adhesion signaling by a novel mitotic substrate of src kinases.
PubMed ID: 16007225
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 26091039
Title: A single kinase generates the majority of the secreted phosphoproteome.
PubMed ID: 26091039
PubMed ID: 28169360
Title: Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway.
PubMed ID: 28169360
DOI: 10.1038/srep42125
PubMed ID: 32341084
Title: Fbxo45 Binds SPRY Motifs in the Extracellular Domain of N-Cadherin and Regulates Neuron Migration during Brain Development.
PubMed ID: 32341084
DOI: 10.1128/mcb.00539-19
PubMed ID: 28280076
Title: Identification of cadherin 2 (CDH2) mutations in arrhythmogenic right ventricular cardiomyopathy.
PubMed ID: 28280076
PubMed ID: 28326674
Title: Whole exome sequencing with genomic triangulation implicates CDH2-encoded N-cadherin as a novel pathogenic substrate for arrhythmogenic cardiomyopathy.
PubMed ID: 28326674
DOI: 10.1111/chd.12462
PubMed ID: 31585109
Title: De novo pathogenic variants in N-cadherin cause a syndromic neurodevelopmental disorder with corpus collosum, axon, cardiac, ocular, and genital defects.
PubMed ID: 31585109
PubMed ID: 31650526
Title: Novel variants in CDH2 are associated with a new syndrome including Peters anomaly.
PubMed ID: 31650526
DOI: 10.1111/cge.13660
PubMed ID: 34702855
Title: CDH2 mutation affecting N-cadherin function causes attention-deficit hyperactivity disorder in humans and mice.
PubMed ID: 34702855
Sequence Information:
- Length: 906
- Mass: 99809
- Checksum: 7267E2A00489DF94
- Sequence:
MCRIAGALRT LLPLLAALLQ ASVEASGEIA LCKTGFPEDV YSAVLSKDVH EGQPLLNVKF SNCNGKRKVQ YESSEPADFK VDEDGMVYAV RSFPLSSEHA KFLIYAQDKE TQEKWQVAVK LSLKPTLTEE SVKESAEVEE IVFPRQFSKH SGHLQRQKRD WVIPPINLPE NSRGPFPQEL VRIRSDRDKN LSLRYSVTGP GADQPPTGIF IINPISGQLS VTKPLDREQI ARFHLRAHAV DINGNQVENP IDIVINVIDM NDNRPEFLHQ VWNGTVPEGS KPGTYVMTVT AIDADDPNAL NGMLRYRIVS QAPSTPSPNM FTINNETGDI ITVAAGLDRE KVQQYTLIIQ ATDMEGNPTY GLSNTATAVI TVTDVNDNPP EFTAMTFYGE VPENRVDIIV ANLTVTDKDQ PHTPAWNAVY RISGGDPTGR FAIQTDPNSN DGLVTVVKPI DFETNRMFVL TVAAENQVPL AKGIQHPPQS TATVSVTVID VNENPYFAPN PKIIRQEEGL HAGTMLTTFT AQDPDRYMQQ NIRYTKLSDP ANWLKIDPVN GQITTIAVLD RESPNVKNNI YNATFLASDN GIPPMSGTGT LQIYLLDIND NAPQVLPQEA ETCETPDPNS INITALDYDI DPNAGPFAFD LPLSPVTIKR NWTITRLNGD FAQLNLKIKF LEAGIYEVPI IITDSGNPPK SNISILRVKV CQCDSNGDCT DVDRIVGAGL GTGAIIAILL CIIILLILVL MFVVWMKRRD KERQAKQLLI DPEDDVRDNI LKYDEEGGGE EDQDYDLSQL QQPDTVEPDA IKPVGIRRMD ERPIHAEPQY PVRSAAPHPG DIGDFINEGL KAADNDPTAP PYDSLLVFDY EGSGSTAGSL SSLNSSSSGG EQDYDYLNDW GPRFKKLADM YGGGDD
Genular Protein ID: 407073305
Symbol: C9J126_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16177791
Title: DNA sequence and analysis of human chromosome 18.
PubMed ID: 16177791
DOI: 10.1038/nature03983
Sequence Information:
- Length: 821
- Mass: 90673
- Checksum: 3E288C4557CA8D30
- Sequence:
MVYAVRSFPL SSEHAKFLIY AQDKETQEKW QVAVKLSLKP TLTEESVKES AEVEEIVFPR QFSKHSGHLQ RQKRDWVIPP INLPENSRGP FPQELVRIRS DRDKNLSLRY SVTGPGADQP PTGIFIINPI SGQLSVTKPL DREQIARFHL RAHAVDINGN QVENPIDIVI NVIDMNDNRP EFLHQVWNGT VPEGSKPGTY VMTVTAIDAD DPNALNGMLR YRIVSQAPST PSPNMFTINN ETGDIITVAA GLDREKVQQY TLIIQATDME GNPTYGLSNT ATAVITVTDV NDNPPEFTAM TFYGEVPENR VDIIVANLTV TDKDQPHTPA WNAVYRISGG DPTGRFAIQT DPNSNDGLVT VVKPIDFETN RMFVLTVAAE NQVPLAKGIQ HPPQSTATVS VTVIDVNENP YFAPNPKIIR QEEGLHAGTM LTTFTAQDPD RYMQQNIRYT KLSDPANWLK IDPVNGQITT IAVLDRESPN VKNNIYNATF LASDNGIPPM SGTGTLQIYL LDINDNAPQV LPQEAETCET PDPNSINITA LDYDIDPNAG PFAFDLPLSP VTIKRNWTIT RLNGDFAQLN LKIKFLEAGI YEVPIIITDS GNPPKSNISI LRVKVCQCDS NGDCTDVDRI VGAGLGTGAI IAILLCIIIL LILVLMFVVW MKRRDKERQA KQLLIDPEDD VRDNILKYDE EGGGEEDQDY DLSQLQQPDT VEPDAIKPVG IRRMDERPIH AEPQYPVRSA APHPGDIGDF INEGLKAADN DPTAPPYDSL LVFDYEGSGS TAGSLSSLNS SSSGGEQDYD YLNDWGPRFK KLADMYGGGD D
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.