Details for: NR2E3

Gene ID: 10002

Symbol: NR2E3

Ensembl ID: ENSG00000278570

Description: nuclear receptor subfamily 2 group E member 3

Associated with

Other Information

Genular Protein ID: 4183579113

Symbol: NR2E3_HUMAN

Name: Photoreceptor-specific nuclear receptor

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10220376

Title: Identification of a photoreceptor cell-specific nuclear receptor.

PubMed ID: 10220376

DOI: 10.1073/pnas.96.9.4814

PubMed ID: 10611353

Title: Retina-specific nuclear receptor: a potential regulator of cellular retinaldehyde-binding protein expressed in retinal pigment epithelium and Muller glial cells.

PubMed ID: 10611353

DOI: 10.1073/pnas.96.26.15149

PubMed ID: 15689355

Title: The photoreceptor-specific nuclear receptor Nr2e3 interacts with Crx and exerts opposing effects on the transcription of rod versus cone genes.

PubMed ID: 15689355

DOI: 10.1093/hmg/ddi070

PubMed ID: 24069298

Title: The crystal structure of the orphan nuclear receptor NR2E3/PNR ligand binding domain reveals a dimeric auto-repressed conformation.

PubMed ID: 24069298

DOI: 10.1371/journal.pone.0074359

PubMed ID: 11071390

Title: The photoreceptor cell-specific nuclear receptor gene (PNR) accounts for retinitis pigmentosa in the Crypto-Jews from Portugal (Marranos), survivors from the Spanish Inquisition.

PubMed ID: 11071390

DOI: 10.1007/s004390000350

PubMed ID: 10655056

Title: Mutation of a nuclear receptor gene, NR2E3, causes enhanced S cone syndrome, a disorder of retinal cell fate.

PubMed ID: 10655056

DOI: 10.1038/72777

PubMed ID: 12963616

Title: Shared mutations in NR2E3 in enhanced S-cone syndrome, Goldmann-Favre syndrome, and many cases of clumped pigmentary retinal degeneration.

PubMed ID: 12963616

DOI: 10.1001/archopht.121.9.1316

PubMed ID: 15459973

Title: Mutation analysis of NR2E3 and NRL genes in enhanced S cone syndrome.

PubMed ID: 15459973

DOI: 10.1002/humu.9285

PubMed ID: 16225923

Title: Novel NR2E3 mutations (R104Q, R334G) associated with a mild form of enhanced S-cone syndrome demonstrate compound heterozygosity.

PubMed ID: 16225923

DOI: 10.1016/j.ophtha.2005.07.002

PubMed ID: 17564971

Title: Recurrent mutation in the first zinc finger of the orphan nuclear receptor NR2E3 causes autosomal dominant retinitis pigmentosa.

PubMed ID: 17564971

DOI: 10.1086/518426

PubMed ID: 18294254

Title: Analysis of the involvement of the NR2E3 gene in autosomal recessive retinal dystrophies.

PubMed ID: 18294254

DOI: 10.1111/j.1399-0004.2008.00963.x

PubMed ID: 19006237

Title: Mutations in NR2E3 can cause dominant or recessive retinal degenerations in the same family.

PubMed ID: 19006237

DOI: 10.1002/humu.20858

Sequence Information:

  • Length: 410
  • Mass: 44692
  • Checksum: D49525830ED0A000
  • Sequence:
  • METRPTALMS STVAAAAPAA GAASRKESPG RWGLGEDPTG VSPSLQCRVC GDSSSGKHYG 
    IYACNGCSGF FKRSVRRRLI YRCQVGAGMC PVDKAHRNQC QACRLKKCLQ AGMNQDAVQN 
    ERQPRSTAQV HLDSMESNTE SRPESLVAPP APAGRSPRGP TPMSAARALG HHFMASLITA 
    ETCAKLEPED ADENIDVTSN DPEFPSSPYS SSSPCGLDSI HETSARLLFM AVKWAKNLPV 
    FSSLPFRDQV ILLEEAWSEL FLLGAIQWSL PLDSCPLLAP PEASAAGGAQ GRLTLASMET 
    RVLQETISRF RALAVDPTEF ACMKALVLFK PETRGLKDPE HVEALQDQSQ VMLSQHSKAH 
    HPSQPVRFGK LLLLLPSLRF ITAERIELLF FRKTIGNTPM EKLLCDMFKN

Genular Protein ID: 1134739593

Symbol: F1D8Q9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 367
  • Mass: 39638
  • Checksum: F67A09D430754B3D
  • Sequence:
  • METRPTALMS STVAAAAPAA GAASRKESPG RWGLGEDPTG VSPSLQCRVC GDSSSGKHYG 
    IYACNGCSGF FKRSVRRRLI YRCQVGAGMC PVDKAHRNQC QACRLKKCLQ AGMNQDAVQN 
    ERQPRSTAQV HLDSMESNTE SRPESLVAPP APAGRSPRGP TPMSAARALG HHFMASLITA 
    ETCAKLEPED ADENIDVTSN DPEFPSSPYS SSSPCGLDSI HETSARLLFM AVKWAKNLPV 
    FSSLPFRDQV ILLEEAWSEL FLLGAIQWSL PLDSCPLLAP PEASAAGGAQ GRLTLASMET 
    RVLQETISRF RALAVDPTEF ACMKALVLFK PETRGLKDPE HVEALQDQSQ VMLSQHSKAH 
    HPSQPVR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.