Details for: TANK

Gene ID: 10010

Symbol: TANK

Ensembl ID: ENSG00000136560

Description: TRAF family member associated NFKB activator

Associated with

Other Information

Genular Protein ID: 3269140797

Symbol: TANK_HUMAN

Name: TRAF family member-associated NF-kappa-B activator

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8710854

Title: I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction.

PubMed ID: 8710854

DOI: 10.1073/pnas.93.16.8241

PubMed ID: 8855313

Title: Tumor necrosis factor receptor associated factor 2 is a mediator of NF-kappa B activation by latent infection membrane protein 1, the Epstein-Barr virus transforming protein.

PubMed ID: 8855313

DOI: 10.1073/pnas.93.20.11085

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10581243

Title: NF-kB activation by a signaling complex containing TRAF2, TANK, and TBK1, a novel IKK-related kinase.

PubMed ID: 10581243

DOI: 10.1093/emboj/18.23.6694

PubMed ID: 10759890

Title: NF-kappaB activation through IKK-i-dependent I-TRAF/TANK phosphorylation.

PubMed ID: 10759890

DOI: 10.1046/j.1365-2443.2000.00315.x

PubMed ID: 12133833

Title: Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases.

PubMed ID: 12133833

DOI: 10.1074/jbc.m205069200

PubMed ID: 17568778

Title: SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK.

PubMed ID: 17568778

DOI: 10.1038/sj.emboj.7601743

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21931631

Title: Functional dissection of the TBK1 molecular network.

PubMed ID: 21931631

DOI: 10.1371/journal.pone.0023971

PubMed ID: 21931555

Title: Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7.

PubMed ID: 21931555

DOI: 10.1371/journal.ppat.1002247

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25861989

Title: TRAF family member-associated NF-kappaB activator (TANK) inhibits genotoxic nuclear factor kappaB activation by facilitating deubiquitinase USP10-dependent deubiquitination of TRAF6 ligase.

PubMed ID: 25861989

DOI: 10.1074/jbc.m115.643767

PubMed ID: 26363073

Title: Encephalomyocarditis Virus 3C Protease Relieves TRAF Family Member-associated NF-kappaB Activator (TANK) Inhibitory Effect on TRAF6-mediated NF-kappaB Signaling through Cleavage of TANK.

PubMed ID: 26363073

DOI: 10.1074/jbc.m115.660761

PubMed ID: 28487378

Title: Encephalomyocarditis virus 3C protease attenuates type I interferon production through disrupting the TANK-TBK1-IKKepsilon-IRF3 complex.

PubMed ID: 28487378

DOI: 10.1042/bcj20161037

PubMed ID: 28566380

Title: Seneca Valley virus suppresses host type I interferon production by targeting adaptor proteins MAVS, TRIF, and TANK for cleavage.

PubMed ID: 28566380

DOI: 10.1128/jvi.00823-17

PubMed ID: 29251827

Title: Quantitative Proteomics Identified TTC4 as a TBK1 Interactor and a Positive Regulator of SeV-Induced Innate Immunity.

PubMed ID: 29251827

DOI: 10.1002/pmic.201700403

PubMed ID: 12005438

Title: Downstream regulator TANK binds to the CD40 recognition site on TRAF3.

PubMed ID: 12005438

DOI: 10.1016/s0969-2126(02)00733-5

Sequence Information:

  • Length: 425
  • Mass: 47816
  • Checksum: 718D30CF03EB27FF
  • Sequence:
  • MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS 
    QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV RRQEVSSPRK 
    ETSARSLGSP LLHERGNIEK TFWDLKEEFH KICMLAKAQK DHLSKLNIPD TATETQCSVP 
    IQCTDKTDKQ EALFKPQAKD DINRGAPSIT SVTPRGLCRD EEDTSFESLS KFNVKFPPMD 
    NDSTFLHSTP ERPGILSPAT SEAVCQEKFN MEFRDNPGNF VKTEETLFEI QGIDPIASAI 
    QNLKTTDKTK PSNLVNTCIR TTLDRAACLP PGDHNALYVN SFPLLDPSDA PFPSLDSPGK 
    AIRGPQQPIW KPFPNQDSDS VVLSGTDSEL HIPRVCEFCQ AVFPPSITSR GDFLRHLNSH 
    FNGET

Genular Protein ID: 928804385

Symbol: B2R7S3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 425
  • Mass: 47786
  • Checksum: 7D3BEBAE06BA62EE
  • Sequence:
  • MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS 
    QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV RRQEVSSPRK 
    ETSARSLGSP LLHERGNIEK AFWDLKEEFH KICMLAKAQK DHLSKLNIPD TATETQCSVP 
    IQCTDKTDKQ EALFKPQAKD DINRGAPSIT SVTPRGLCRD EEDTSFESLS KFNVKFPPMD 
    NDSTFLHSTP ERPGILSPAT SEAVCQEKFN MEFRDNPGNF VKTEETLFEI QGIDPIASAI 
    QNLKTTDKTK PSNLVNTCIR TTLDRAACLP PGDHNALYVN SFPLLDPSDA PFPSLDSPGK 
    AIRGPQQPIW KPFPNQDSDS VVLSGTDSEL HIPRVCEFCQ AVFPPSITSR GDFLRHLNSH 
    FNGET

Genular Protein ID: 3564954465

Symbol: Q6NW12_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 425
  • Mass: 47844
  • Checksum: 622FB7B67920C9EF
  • Sequence:
  • MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS 
    QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV RRQEVSSPRK 
    ETSARSLGSP LLHERGNIEK TFWDLKEEFH KICMLAKAQK DHLSKLNIPD TATETQCSVP 
    IQCTDKTDKQ EALFKPQAKD DINRGAPSIT SVTPRGLCRD EEDTSFESLS KFNVKFPPMD 
    NDSTFLHSTP ERPGILSPAT SEVVCQEKFN MEFRDNPGNF VKTEETLFEI QGIDPIASAI 
    QNLKTTDKTK PSNLVNTCIR TTLDRAACLP PGDHNALYVN SFPLLDPSDA PFPSLDSPGK 
    AIRGPQQPIW KPFPNQDSDS VVLSGTDSEL HIPRVCEFCQ AVFPPSITSR GDFLRHLNSH 
    FNGET

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.