Details for: TANK

Gene ID: 10010

Symbol: TANK

Ensembl ID: ENSG00000136560

Description: TRAF family member associated NFKB activator

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.27
    Marker Score: 2,613
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.15
    Marker Score: 4,724
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 2.13
    Marker Score: 1,183
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.93
    Marker Score: 1,080
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.93
    Marker Score: 936
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.92
    Marker Score: 1,261
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 1.89
    Marker Score: 6,193
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.87
    Marker Score: 546
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.83
    Marker Score: 39,051
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 1.81
    Marker Score: 1,781
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.79
    Marker Score: 3,437
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.78
    Marker Score: 1,237
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.76
    Marker Score: 18,207
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.75
    Marker Score: 28,084
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 1.75
    Marker Score: 8,580
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 1.73
    Marker Score: 1,366
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.73
    Marker Score: 1,864
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.69
    Marker Score: 1,803
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 1.67
    Marker Score: 2,021
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 1.67
    Marker Score: 959
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 1.67
    Marker Score: 1,004
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.66
    Marker Score: 619
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 1.65
    Marker Score: 16,342
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.63
    Marker Score: 55,530
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.61
    Marker Score: 15,100
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.59
    Marker Score: 1,754
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.58
    Marker Score: 2,332
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.57
    Marker Score: 1,393
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.57
    Marker Score: 452
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 1.57
    Marker Score: 979
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.56
    Marker Score: 57,674
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.56
    Marker Score: 773
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.55
    Marker Score: 1,628
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.53
    Marker Score: 85,817
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.53
    Marker Score: 914
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.52
    Marker Score: 617
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.52
    Marker Score: 1,314
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.5
    Marker Score: 29,852
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.49
    Marker Score: 357
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.49
    Marker Score: 14,197
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.49
    Marker Score: 1,852
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.49
    Marker Score: 91,347
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 1.48
    Marker Score: 935
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.48
    Marker Score: 12,704
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.47
    Marker Score: 6,002
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 1.47
    Marker Score: 2,567
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 1.44
    Marker Score: 316
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.44
    Marker Score: 9,234
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.43
    Marker Score: 1,316
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.42
    Marker Score: 351
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.42
    Marker Score: 7,625
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.41
    Marker Score: 6,094
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 1.41
    Marker Score: 2,501
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 1.41
    Marker Score: 499
  • Cell Name: progenitor cell of endocrine pancreas (CL0002351)
    Fold Change: 1.4
    Marker Score: 305
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 1.4
    Marker Score: 1,062
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.4
    Marker Score: 3,423
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 1.4
    Marker Score: 511
  • Cell Name: cardiac mesenchymal cell (CL0000569)
    Fold Change: 1.39
    Marker Score: 342
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.37
    Marker Score: 5,700
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 1.37
    Marker Score: 559
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 1.37
    Marker Score: 939
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.36
    Marker Score: 8,704
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 1.36
    Marker Score: 1,595
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.36
    Marker Score: 353
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 1.36
    Marker Score: 474
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.35
    Marker Score: 500
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 1.35
    Marker Score: 467
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.34
    Marker Score: 50,942
  • Cell Name: Schwann cell precursor (CL0002375)
    Fold Change: 1.34
    Marker Score: 333
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.33
    Marker Score: 2,059
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.33
    Marker Score: 305
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 1.31
    Marker Score: 801
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.31
    Marker Score: 5,082
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 1.31
    Marker Score: 3,273
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.31
    Marker Score: 333
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 1.31
    Marker Score: 5,445
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.3
    Marker Score: 5,449
  • Cell Name: type I enteroendocrine cell (CL0002277)
    Fold Change: 1.3
    Marker Score: 324
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 1.3
    Marker Score: 739
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 1.29
    Marker Score: 468
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: 1.28
    Marker Score: 753
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.28
    Marker Score: 5,534
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.28
    Marker Score: 481
  • Cell Name: peritubular capillary endothelial cell (CL1001033)
    Fold Change: 1.27
    Marker Score: 296
  • Cell Name: pre-B-I cell (CL0000956)
    Fold Change: 1.27
    Marker Score: 325
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 1.27
    Marker Score: 32,569
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 1.27
    Marker Score: 337
  • Cell Name: tracheobronchial goblet cell (CL0019003)
    Fold Change: 1.27
    Marker Score: 348
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 1.27
    Marker Score: 3,062
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.27
    Marker Score: 1,794
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 1.27
    Marker Score: 1,378
  • Cell Name: glomerular endothelial cell (CL0002188)
    Fold Change: 1.26
    Marker Score: 321
  • Cell Name: smooth muscle cell of small intestine (CL1000275)
    Fold Change: 1.26
    Marker Score: 329
  • Cell Name: mesenchymal lymphangioblast (CL0005021)
    Fold Change: 1.25
    Marker Score: 280
  • Cell Name: megakaryocyte progenitor cell (CL0000553)
    Fold Change: 1.25
    Marker Score: 350
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.25
    Marker Score: 43,365
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.25
    Marker Score: 454
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 1.25
    Marker Score: 8,150
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 1.25
    Marker Score: 387

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** TANK is a cytoplasmic protein that contains a single transmembrane domain and a coiled-coil region. It is a negative regulator of the NF-κB signaling pathway, which is activated by various stimuli, including TNF-α, IL-1β, and LPS. TANK interacts with TRAF6, a key adaptor protein in the NF-κB signaling pathway, to inhibit its activation. In contrast, TANK interacts with TBK1, a kinase that phosphorylates IRF3 and IRF7, leading to the activation of the IFN-α/β pathway. TANK has also been shown to interact with other proteins, including DDX58 and IFIH1, which are involved in the regulation of IFN-α/β production. **Pathways and Functions** The TANK gene is involved in several key signaling pathways, including: 1. **Activation of IFN-α/β pathway**: TANK interacts with TBK1 to activate the IFN-α/β pathway, which is crucial for the innate immune response against viral infections. 2. **Negative regulation of NF-κB signaling pathway**: TANK interacts with TRAF6 to inhibit NF-κB activation, which is involved in inflammation and immune responses. 3. **Cytosol-mediated deubiquitination**: TANK has been shown to have deubiquitinating activity, which regulates the activity of other proteins involved in the immune response. 4. **Interferon-stimulated gene 15 (ISG15) pathway**: TANK has been shown to interact with ISG15, a ubiquitin-like protein that regulates the activity of other proteins involved in the immune response. **Clinical Significance** The TANK gene has been implicated in various diseases, including: 1. **Viral infections**: TANK has been shown to play a critical role in the regulation of IFN-α/β production, which is involved in the innate immune response against viral infections. 2. **Autoimmune diseases**: TANK has been implicated in the pathogenesis of autoimmune diseases, such as rheumatoid arthritis and lupus, due to its involvement in the regulation of NF-κB signaling pathways. 3. **Cancer**: TANK has been shown to be overexpressed in various types of cancer, including breast cancer and colon cancer, and has been implicated in the regulation of NF-κB signaling pathways. In conclusion, the TANK gene is a critical regulator of innate immunity and has been implicated in various diseases. Further research is needed to fully understand the mechanisms by which TANK regulates the immune response and its role in disease pathogenesis.

Genular Protein ID: 3269140797

Symbol: TANK_HUMAN

Name: TRAF family member-associated NF-kappa-B activator

UniProtKB Accession Codes:

Q92844 D3DPB5 Q7Z4J6 Q92885

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChEBI 4 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 EPD 1 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 20 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 3 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 3 RefSeq 5 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8710854

Title: I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction.

PubMed ID: 8710854

DOI: 10.1073/pnas.93.16.8241

PubMed ID: 8855313

Title: Tumor necrosis factor receptor associated factor 2 is a mediator of NF-kappa B activation by latent infection membrane protein 1, the Epstein-Barr virus transforming protein.

PubMed ID: 8855313

DOI: 10.1073/pnas.93.20.11085

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10581243

Title: NF-kB activation by a signaling complex containing TRAF2, TANK, and TBK1, a novel IKK-related kinase.

PubMed ID: 10581243

DOI: 10.1093/emboj/18.23.6694

PubMed ID: 10759890

Title: NF-kappaB activation through IKK-i-dependent I-TRAF/TANK phosphorylation.

PubMed ID: 10759890

DOI: 10.1046/j.1365-2443.2000.00315.x

PubMed ID: 12133833

Title: Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases.

PubMed ID: 12133833

DOI: 10.1074/jbc.m205069200

PubMed ID: 17568778

Title: SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK.

PubMed ID: 17568778

DOI: 10.1038/sj.emboj.7601743

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21931631

Title: Functional dissection of the TBK1 molecular network.

PubMed ID: 21931631

DOI: 10.1371/journal.pone.0023971

PubMed ID: 21931555

Title: Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7.

PubMed ID: 21931555

DOI: 10.1371/journal.ppat.1002247

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25861989

Title: TRAF family member-associated NF-kappaB activator (TANK) inhibits genotoxic nuclear factor kappaB activation by facilitating deubiquitinase USP10-dependent deubiquitination of TRAF6 ligase.

PubMed ID: 25861989

DOI: 10.1074/jbc.m115.643767

PubMed ID: 26363073

Title: Encephalomyocarditis Virus 3C Protease Relieves TRAF Family Member-associated NF-kappaB Activator (TANK) Inhibitory Effect on TRAF6-mediated NF-kappaB Signaling through Cleavage of TANK.

PubMed ID: 26363073

DOI: 10.1074/jbc.m115.660761

PubMed ID: 28487378

Title: Encephalomyocarditis virus 3C protease attenuates type I interferon production through disrupting the TANK-TBK1-IKKepsilon-IRF3 complex.

PubMed ID: 28487378

DOI: 10.1042/bcj20161037

PubMed ID: 28566380

Title: Seneca Valley virus suppresses host type I interferon production by targeting adaptor proteins MAVS, TRIF, and TANK for cleavage.

PubMed ID: 28566380

DOI: 10.1128/jvi.00823-17

PubMed ID: 29251827

Title: Quantitative Proteomics Identified TTC4 as a TBK1 Interactor and a Positive Regulator of SeV-Induced Innate Immunity.

PubMed ID: 29251827

DOI: 10.1002/pmic.201700403

PubMed ID: 12005438

Title: Downstream regulator TANK binds to the CD40 recognition site on TRAF3.

PubMed ID: 12005438

DOI: 10.1016/s0969-2126(02)00733-5

Sequence Information:

  • Length: 425
  • Mass: 47816
  • Checksum: 718D30CF03EB27FF
  • Sequence:
    • MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS 
QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV RRQEVSSPRK 
ETSARSLGSP LLHERGNIEK TFWDLKEEFH KICMLAKAQK DHLSKLNIPD TATETQCSVP 
IQCTDKTDKQ EALFKPQAKD DINRGAPSIT SVTPRGLCRD EEDTSFESLS KFNVKFPPMD 
NDSTFLHSTP ERPGILSPAT SEAVCQEKFN MEFRDNPGNF VKTEETLFEI QGIDPIASAI 
QNLKTTDKTK PSNLVNTCIR TTLDRAACLP PGDHNALYVN SFPLLDPSDA PFPSLDSPGK 
AIRGPQQPIW KPFPNQDSDS VVLSGTDSEL HIPRVCEFCQ AVFPPSITSR GDFLRHLNSH 
FNGET

Genular Protein ID: 928804385

Symbol: B2R7S3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2R7S3

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 1 Genevisible 1 GenomeRNAi 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1

Sequence Information:

  • Length: 425
  • Mass: 47786
  • Checksum: 7D3BEBAE06BA62EE
  • Sequence:
    • MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS 
QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV RRQEVSSPRK 
ETSARSLGSP LLHERGNIEK AFWDLKEEFH KICMLAKAQK DHLSKLNIPD TATETQCSVP 
IQCTDKTDKQ EALFKPQAKD DINRGAPSIT SVTPRGLCRD EEDTSFESLS KFNVKFPPMD 
NDSTFLHSTP ERPGILSPAT SEAVCQEKFN MEFRDNPGNF VKTEETLFEI QGIDPIASAI 
QNLKTTDKTK PSNLVNTCIR TTLDRAACLP PGDHNALYVN SFPLLDPSDA PFPSLDSPGK 
AIRGPQQPIW KPFPNQDSDS VVLSGTDSEL HIPRVCEFCQ AVFPPSITSR GDFLRHLNSH 
FNGET

Genular Protein ID: 3564954465

Symbol: Q6NW12_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6NW12

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 1 Genevisible 1 GenomeRNAi 1 IntAct 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 425
  • Mass: 47844
  • Checksum: 622FB7B67920C9EF
  • Sequence:
    • MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS 
QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV RRQEVSSPRK 
ETSARSLGSP LLHERGNIEK TFWDLKEEFH KICMLAKAQK DHLSKLNIPD TATETQCSVP 
IQCTDKTDKQ EALFKPQAKD DINRGAPSIT SVTPRGLCRD EEDTSFESLS KFNVKFPPMD 
NDSTFLHSTP ERPGILSPAT SEVVCQEKFN MEFRDNPGNF VKTEETLFEI QGIDPIASAI 
QNLKTTDKTK PSNLVNTCIR TTLDRAACLP PGDHNALYVN SFPLLDPSDA PFPSLDSPGK 
AIRGPQQPIW KPFPNQDSDS VVLSGTDSEL HIPRVCEFCQ AVFPPSITSR GDFLRHLNSH 
FNGET

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.