Details for: PDCD6IP
Associated with
Other Information
Genular Protein ID: 937100981
Symbol: PDC6I_HUMAN
Name: Programmed cell death 6-interacting protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11683497
Title: Overexpression of Hp95 induces G1 phase arrest in confluent HeLa cells.
PubMed ID: 11683497
PubMed ID: 19906316
Title: Discovery of novel human transcript variants by analysis of intronic single-block EST with polyadenylation site.
PubMed ID: 19906316
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 10718198
Title: Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10718198
PubMed ID: 12860994
Title: The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting.
PubMed ID: 12860994
PubMed ID: 14505569
Title: AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding.
PubMed ID: 14505569
PubMed ID: 14505570
PubMed ID: 14519844
Title: Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins.
PubMed ID: 14519844
PubMed ID: 14678797
Title: CHMP4b is a major binding partner of the ALG-2-interacting protein Alix among the three CHMP4 isoforms.
PubMed ID: 14678797
PubMed ID: 14583093
Title: Structure and function of human Vps20 and Snf7 proteins.
PubMed ID: 14583093
DOI: 10.1042/bj20031347
PubMed ID: 14739459
Title: Role of LBPA and Alix in multivesicular liposome formation and endosome organization.
PubMed ID: 14739459
PubMed ID: 15849434
Title: Identification of Rab GTPase-activating protein-like protein (RabGAPLP) as a novel Alix/AIP1-interacting protein.
PubMed ID: 15849434
DOI: 10.1271/bbb.69.861
PubMed ID: 15908698
Title: Tsg101 and Alix interact with murine leukemia virus Gag and cooperate with Nedd4 ubiquitin ligases during budding.
PubMed ID: 15908698
PubMed ID: 17081065
Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.
PubMed ID: 17081065
DOI: 10.1021/pr060363j
PubMed ID: 16957052
Title: The Ca2+-binding protein ALG-2 is recruited to endoplasmic reticulum exit sites by Sec31A and stabilizes the localization of Sec31A.
PubMed ID: 16957052
PubMed ID: 17853893
Title: Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis.
PubMed ID: 17853893
PubMed ID: 17428861
Title: Potent rescue of human immunodeficiency virus type 1 late domain mutants by ALIX/AIP1 depends on its CHMP4 binding site.
PubMed ID: 17428861
DOI: 10.1128/jvi.00314-07
PubMed ID: 17556548
Title: Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery.
PubMed ID: 17556548
PubMed ID: 18256029
Title: Identification of Alix-type and non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants.
PubMed ID: 18256029
PubMed ID: 18641129
Title: Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release.
PubMed ID: 18641129
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19520058
Title: Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101.
PubMed ID: 19520058
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20494825
Title: Mutation of tyrosine residue 857 in the PDGF beta-receptor affects cell proliferation but not migration.
PubMed ID: 20494825
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21191027
Title: Multiple interactions between the ESCRT machinery and arrestin-related proteins: implications for PPXY-dependent budding.
PubMed ID: 21191027
DOI: 10.1128/jvi.02045-10
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22660413
Title: Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.
PubMed ID: 22660413
DOI: 10.1038/ncb2502
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 25786915
Title: ALIX Rescues Budding of a Double PTAP/PPEY L-Domain Deletion Mutant of Ebola VP40: A Role for ALIX in Ebola Virus Egress.
PubMed ID: 25786915
PubMed ID: 32286682
Title: PDCD6IP, encoding a regulator of the ESCRT complex, is mutated in microcephaly.
PubMed ID: 32286682
DOI: 10.1111/cge.13756
PubMed ID: 17350572
Title: Structural and biochemical studies of ALIX/AIP1 and its role in retrovirus budding.
PubMed ID: 17350572
PubMed ID: 17277784
Title: Structural basis for viral late-domain binding to Alix.
PubMed ID: 17277784
DOI: 10.1038/nsmb1203
PubMed ID: 18066081
Title: Structural and functional studies of ALIX interactions with YPX(n)L late domains of HIV-1 and EIAV.
PubMed ID: 18066081
DOI: 10.1038/nsmb1319
PubMed ID: 18511562
Title: ALIX-CHMP4 interactions in the human ESCRT pathway.
PubMed ID: 18511562
PubMed ID: 18948538
Title: Midbody targeting of the ESCRT machinery by a noncanonical coiled coil in CEP55.
PubMed ID: 18948538
PubMed ID: 18940611
Title: Structural basis for Ca2+ -dependent formation of ALG-2/Alix peptide complex: Ca2+/EF3-driven arginine switch mechanism.
PubMed ID: 18940611
PubMed ID: 22073189
Title: Exome-sequencing confirms DNAJC5 mutations as cause of adult neuronal ceroid-lipofuscinosis.
PubMed ID: 22073189
Sequence Information:
- Length: 868
- Mass: 96023
- Checksum: 573588D1F612EC93
- Sequence:
MATFISVQLK KTSEVDLAKP LVKFIQQTYP SGGEEQAQYC RAAEELSKLR RAAVGRPLDK HEGALETLLR YYDQICSIEP KFPFSENQIC LTFTWKDAFD KGSLFGGSVK LALASLGYEK SCVLFNCAAL ASQIAAEQNL DNDEGLKIAA KHYQFASGAF LHIKETVLSA LSREPTVDIS PDTVGTLSLI MLAQAQEVFF LKATRDKMKD AIIAKLANQA ADYFGDAFKQ CQYKDTLPKE VFPVLAAKHC IMQANAEYHQ SILAKQQKKF GEEIARLQHA AELIKTVASR YDEYVNVKDF SDKINRALAA AKKDNDFIYH DRVPDLKDLD PIGKATLVKS TPVNVPISQK FTDLFEKMVP VSVQQSLAAY NQRKADLVNR SIAQMREATT LANGVLASLN LPAAIEDVSG DTVPQSILTK SRSVIEQGGI QTVDQLIKEL PELLQRNREI LDESLRLLDE EEATDNDLRA KFKERWQRTP SNELYKPLRA EGTNFRTVLD KAVQADGQVK ECYQSHRDTI VLLCKPEPEL NAAIPSANPA KTMQGSEVVN VLKSLLSNLD EVKKEREGLE NDLKSVNFDM TSKFLTALAQ DGVINEEALS VTELDRVYGG LTTKVQESLK KQEGLLKNIQ VSHQEFSKMK QSNNEANLRE EVLKNLATAY DNFVELVANL KEGTKFYNEL TEILVRFQNK CSDIVFARKT ERDELLKDLQ QSIAREPSAP SIPTPAYQSS PAGGHAPTPP TPAPRTMPPT KPQPPARPPP PVLPANRAPS ATAPSPVGAG TAAPAPSQTP GSAPPPQAQG PPYPTYPGYP GYCQMPMPMG YNPYAYGQYN MPYPPVYHQS PGQAPYPGPQ QPSYPFPQPP QQSYYPQQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.