Details for: SH2B3
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.51
Marker Score: 472 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.46
Marker Score: 471 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 1.44
Marker Score: 718 - Cell Name: lung macrophage (CL1001603)
Fold Change: 1.38
Marker Score: 1,574 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.36
Marker Score: 1,254 - Cell Name: eurydendroid cell (CL0000253)
Fold Change: 1.31
Marker Score: 535 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 1.29
Marker Score: 1,559 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.28
Marker Score: 2,604 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 1.28
Marker Score: 1,277 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.27
Marker Score: 19,927 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.18
Marker Score: 712 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 1.14
Marker Score: 29,135 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.12
Marker Score: 656 - Cell Name: non-classical monocyte (CL0000875)
Fold Change: 1.12
Marker Score: 2,694 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 1.08
Marker Score: 60,512 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 1.06
Marker Score: 2,073 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 1.04
Marker Score: 251,729 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,747 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,972 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 0.99
Marker Score: 22,087 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.98
Marker Score: 1,130 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,399 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 0.98
Marker Score: 922 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,405 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 0.95
Marker Score: 237 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.94
Marker Score: 483 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.93
Marker Score: 438 - Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
Fold Change: 0.91
Marker Score: 2,363 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.91
Marker Score: 2,147 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,717 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.89
Marker Score: 54,836 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 0.89
Marker Score: 1,290 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.87
Marker Score: 4,974 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,253 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.86
Marker Score: 1,330 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 0.86
Marker Score: 310 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 307 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 0.82
Marker Score: 453 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 0.82
Marker Score: 2,042 - Cell Name: elicited macrophage (CL0000861)
Fold Change: 0.8
Marker Score: 4,878 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.8
Marker Score: 4,802 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.79
Marker Score: 776 - Cell Name: macrophage (CL0000235)
Fold Change: 0.79
Marker Score: 881 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.79
Marker Score: 6,779 - Cell Name: microglial cell (CL0000129)
Fold Change: 0.78
Marker Score: 1,427 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.78
Marker Score: 373 - Cell Name: plasmacytoid dendritic cell, human (CL0001058)
Fold Change: 0.78
Marker Score: 204 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.77
Marker Score: 7,289 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 0.77
Marker Score: 1,532 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.76
Marker Score: 306 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.76
Marker Score: 579 - Cell Name: conventional dendritic cell (CL0000990)
Fold Change: 0.76
Marker Score: 522 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.75
Marker Score: 1,225 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.75
Marker Score: 3,128 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.74
Marker Score: 469 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.74
Marker Score: 1,189 - Cell Name: dendritic cell (CL0000451)
Fold Change: 0.74
Marker Score: 505 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.73
Marker Score: 12,961 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 375 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.72
Marker Score: 26,484 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.72
Marker Score: 455 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.71
Marker Score: 6,269 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.71
Marker Score: 6,685 - Cell Name: brush cell (CL0002204)
Fold Change: 0.71
Marker Score: 645 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.69
Marker Score: 1,735 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 0.69
Marker Score: 413 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.68
Marker Score: 285 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 0.68
Marker Score: 1,299 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: 0.67
Marker Score: 262 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 0.67
Marker Score: 445 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.67
Marker Score: 171 - Cell Name: classical monocyte (CL0000860)
Fold Change: 0.66
Marker Score: 2,760 - Cell Name: endothelial cell (CL0000115)
Fold Change: 0.66
Marker Score: 594 - Cell Name: osteoclast (CL0000092)
Fold Change: 0.66
Marker Score: 328 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.66
Marker Score: 272 - Cell Name: transitional stage B cell (CL0000818)
Fold Change: 0.66
Marker Score: 232 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.65
Marker Score: 178 - Cell Name: vein endothelial cell (CL0002543)
Fold Change: 0.64
Marker Score: 578 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 0.64
Marker Score: 2,270 - Cell Name: endothelial tip cell (CL0000704)
Fold Change: 0.63
Marker Score: 147 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 0.63
Marker Score: 675 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.63
Marker Score: 761 - Cell Name: endothelial cell of sinusoid (CL0002262)
Fold Change: 0.63
Marker Score: 152 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.62
Marker Score: 12,380 - Cell Name: dendritic cell, human (CL0001056)
Fold Change: 0.62
Marker Score: 628 - Cell Name: alternatively activated macrophage (CL0000890)
Fold Change: 0.62
Marker Score: 257 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.61
Marker Score: 2,547 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.6
Marker Score: 575 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 0.6
Marker Score: 592 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.6
Marker Score: 155 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.6
Marker Score: 6,158 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.59
Marker Score: 2,490 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.59
Marker Score: 354 - Cell Name: common dendritic progenitor (CL0001029)
Fold Change: 0.58
Marker Score: 202 - Cell Name: lymphocyte (CL0000542)
Fold Change: 0.58
Marker Score: 295 - Cell Name: endothelial cell of lymphatic vessel (CL0002138)
Fold Change: 0.58
Marker Score: 364 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.58
Marker Score: 21,973 - Cell Name: intermediate monocyte (CL0002393)
Fold Change: 0.58
Marker Score: 199 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.56
Marker Score: 177 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 0.56
Marker Score: 134
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4196209216
Symbol: SH2B3_HUMAN
Name: SH2B adapter protein 3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10799879
Title: Cloning and characterization of human Lnk, an adaptor protein with pleckstrin homology and Src homology 2 domains that can inhibit T cell activation.
PubMed ID: 10799879
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17554260
Title: Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.
PubMed ID: 17554260
DOI: 10.1038/ng2068
PubMed ID: 18311140
Title: Newly identified genetic risk variants for celiac disease related to the immune response.
PubMed ID: 18311140
DOI: 10.1038/ng.102
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 20843259
Title: LNK mutations in JAK2 mutation-negative erythrocytosis.
PubMed ID: 20843259
DOI: 10.1056/nejmc1006966
Sequence Information:
- Length: 575
- Mass: 63225
- Checksum: EE30B9E21E0009E5
- Sequence:
MNGPALQPSS PSSAPSASPA AAPRGWSEFC ELHAVAAARE LARQYWLFAR EHPQHAPLRA ELVSLQFTDL FQRYFCREVR DGRAPGRDYR DTGRGPPAKA EASPEPGPGP AAPGLPKARS SEELAPPRPP GPCSFQHFRR SLRHIFRRRS AGELPAAHTA AAPGTPGEAA ETPARPGLAK KFLPWSLARE PPPEALKEAV LRYSLADEAS MDSGARWQRG RLALRRAPGP DGPDRVLELF DPPKSSRPKL QAACSSIQEV RWCTRLEMPD NLYTFVLKVK DRTDIIFEVG DEQQLNSWMA ELSECTGRGL ESTEAEMHIP SALEPSTSSS PRGSTDSLNQ GASPGGLLDP ACQKTDHFLS CYPWFHGPIS RVKAAQLVQL QGPDAHGVFL VRQSETRRGE YVLTFNFQGI AKHLRLSLTE RGQCRVQHLH FPSVVDMLHH FQRSPIPLEC GAACDVRLSS YVVVVSQPPG SCNTVLFPFS LPHWDSESLP HWGSELGLPH LSSSGCPRGL SPEGLPGRSS PPEQIFHLVP SPEELANSLQ HLEHEPVNRA RDSDYEMDSS SRSHLRAIDN QYTPL
Genular Protein ID: 238447371
Symbol: F5GYM4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
Sequence Information:
- Length: 373
- Mass: 41449
- Checksum: 5D8D8631D492A527
- Sequence:
MGFPVLCRGW RRTWPGCASW LGAPPPQKPL LSPLLLNHRS SKSSRPKLQA ACSSIQEVRW CTRLEMPDNL YTFVLKVKDR TDIIFEVGDE QQLNSWMAEL SECTGRGLES TEAEMHIPSA LEPSTSSSPR GSTDSLNQGA SPGGLLDPAC QKTDHFLSCY PWFHGPISRV KAAQLVQLQG PDAHGVFLVR QSETRRGEYV LTFNFQGIAK HLRLSLTERG QCRVQHLHFP SVVDMLHHFQ RSPIPLECGA ACDVRLSSYV VVVSQPPGSC NTVLFPFSLP HWDSESLPHW GSELGLPHLS SSGCPRGLSP EGLPGRSSPP EQIFHLVPSP EELANSLQHL EHEPVNRARD SDYEMDSSSR SHLRAIDNQY TPL
Genular Protein ID: 3422645948
Symbol: B7Z7K6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 373
- Mass: 41419
- Checksum: 5EAEF760D5C08657
- Sequence:
MGFPVLCRGW RRTWPGCASW LGAPPPQKPL LSPLLLNHRS SKSSRPKLQA ACSSIQEVRR CTRLEMPDNL YTFVLKVKDR TDIIFEVGDE QQLNSWMAEL SECTGRGLES TEAEMHIPSA LEPSTSSSPR GSTDSLNQGA SPGGLLDPAC QKTDHFLSCY PWFHGPISRV KAAQLVQLQG PDAHGVFLVR QSETRRGEYV LTFNFQGIAK HLRLSLTERG QCRVQHLHFP SVVDMLHHFQ RSPIPLECGA ACDVRLSSYV VVVSQPPGSC NTVLFPFSLP HWDSESLPHW GSELGLPHLS SSGCPRGLSP EGLPGRSSPP EQIFHLVPSP EELANSLQHL EHEPVNRARD SDYEMDSSSR SHLRAIDNQY TPL
Genular Protein ID: 1056086978
Symbol: Q96BA5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 51
- Mass: 5376
- Checksum: EA64553DA38B6F62
- Sequence:
MEFLLSTGLE CSGAILAHCN LHLPGSSDSA STSQVAGITS TSHHAWLILY F
Genular Protein ID: 18656636
Symbol: Q59H48_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 439
- Mass: 48574
- Checksum: 7663AF5531A10B84
- Sequence:
HFRRSLRHIF RRRSAGELPA AHTAAAPGTP GEAAETPARP GLAKKFLPWS LAREPPPEAL KEAVLRYSLA DEASMDSGAR WQRGRLALRR APGPDGPDRV LELFDPPKSS RPKLQAACSS IQEVRRCTRL EMPDNLYTFV LKVKDRTDII FEVGDEQQLN SWMAELSECT GRGLESTEAE MHIPSALEPS TSSSPRGSTD SLNQGASPGG LLDPACQKTD HFLSCYPWFH GPISRVKAAQ LVQLQGPDAH GVFLVRQSET RRGEYVLTFN FQGIAKHLRL SLTERGQCRV QHLHFPSVVD MLHHFQRSPI PLECGAACDV RLSSYVVVVS QPPGSCNTVL FPFSLPHWDS ESLPHWGSEL GLPHLSSSGC PRGLSPEGLP GRSSPPEQIF HLVPSPEELA NSLQHLEHEP VNRARDSDYE MDSSSRSHLR AIDNQYTPL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.