INSL5 | ENSG00000172410 | NCBI 10022

Details for: INSL5

Gene ID: 10022

Symbol: INSL5

Ensembl ID: ENSG00000172410

Description: insulin like 5

Associated with

Class a/1 (rhodopsin-like receptors)
(R-HSA-373076)
G alpha (i) signalling events
(R-HSA-418594)
Gpcr downstream signalling
(R-HSA-388396)
Gpcr ligand binding
(R-HSA-500792)
Peptide ligand-binding receptors
(R-HSA-375276)
Relaxin receptors
(R-HSA-444821)
Signaling by gpcr
(R-HSA-372790)
Biological_process
(GO:0008150)
Cellular_component
(GO:0005575)
Extracellular region
(GO:0005576)
G protein-coupled receptor binding
(GO:0001664)
Hormone activity
(GO:0005179)
Positive regulation of feeding behavior
(GO:2000253)
Protein binding
(GO:0005515)
Signal transduction
(GO:0007165)

Other Information

Proteins

Insulin-like peptide INSL5

Genular Protein ID: 3231065245

Symbol: INSL5_HUMAN

Name: Insulin-like peptide INSL5

UniProtKB Accession Codes:

Q9Y5Q6 Q3MIY4 Q5VYD8

Database IDs:

Citations:

PubMed ID: 10458910

Title: Identification of INSL5, a new member of the insulin superfamily.

PubMed ID: 10458910

DOI: 10.1006/geno.1999.5899

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 15525639

Title: INSL5 is a high affinity specific agonist for GPCR142 (GPR100).

PubMed ID: 15525639

DOI: 10.1074/jbc.m409916200

PubMed ID: 18576448

Title: Synthesis, conformation, and activity of human insulin-like peptide 5 (INSL5).

PubMed ID: 18576448

DOI: 10.1002/cbic.200800113

PubMed ID: 19178384

Title: Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework.

PubMed ID: 19178384

DOI: 10.1042/bj20082353

Sequence Information:

Length: 135
Mass: 15333
Checksum: A932D7EDE9D173F5
Sequence:

MKGSIFTLFL FSVLFAISEV RSKESVRLCG LEYIRTVIYI CASSRWRRHQ EGIPQAQQAE 
TGNSFQLPHK REFSEENPAQ NLPKVDASGE DRLWGGQMPT EELWKSKKHS VMSRQDLQTL 
CCTDGCSMTD LSALC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: INSL5

Associated with

Other Information

Identification of INSL5, a new member of the insulin superfamily. PubMed ID: 10458910

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Signal peptide prediction based on analysis of experimentally verified cleavage sites. PubMed ID: 15340161

INSL5 is a high affinity specific agonist for GPCR142 (GPR100). PubMed ID: 15525639

Synthesis, conformation, and activity of human insulin-like peptide 5 (INSL5). PubMed ID: 18576448

Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework. PubMed ID: 19178384