MED16 | ENSG00000175221 | NCBI 10025

Details for: MED16

Gene ID: 10025

Symbol: MED16

Ensembl ID: ENSG00000175221

Description: mediator complex subunit 16

Associated with

Developmental biology
(R-HSA-1266738)
Disease
(R-HSA-1643685)
Gene expression (transcription)
(R-HSA-74160)
Generic transcription pathway
(R-HSA-212436)
Infectious disease
(R-HSA-5663205)
Metabolism
(R-HSA-1430728)
Metabolism of lipids
(R-HSA-556833)
Ppara activates gene expression
(R-HSA-1989781)
Regulation of lipid metabolism by pparalpha
(R-HSA-400206)
Respiratory syncytial virus infection pathway
(R-HSA-9820952)
Rna polymerase ii transcription
(R-HSA-73857)
Rsv-host interactions
(R-HSA-9833110)
Transcriptional regulation of white adipocyte differentiation
(R-HSA-381340)
Viral infection pathways
(R-HSA-9824446)
Core mediator complex
(GO:0070847)
Mediator complex
(GO:0016592)
Membrane
(GO:0016020)
Nuclear thyroid hormone receptor binding
(GO:0046966)
Nuclear vitamin d receptor binding
(GO:0042809)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of transcription elongation by rna polymerase ii
(GO:0032968)
Positive regulation of transcription initiation by rna polymerase ii
(GO:0060261)
Protein binding
(GO:0005515)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii preinitiation complex assembly
(GO:0051123)
Transcription by rna polymerase ii
(GO:0006366)
Transcription coactivator activity
(GO:0003713)

Other Information

Proteins

Mediator of RNA polymerase II transcription subunit 16

Genular Protein ID: 948302423

Symbol: MED16_HUMAN

Name: Mediator of RNA polymerase II transcription subunit 16

UniProtKB Accession Codes:

Q9Y2X0 Q6PJT2 Q96AD4 Q96I35 Q9Y652

Database IDs:

Citations:

PubMed ID: 10198638

Title: Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators.

PubMed ID: 10198638

DOI: 10.1016/s1097-2765(00)80463-3

PubMed ID: 10235266

Title: Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.

PubMed ID: 10235266

DOI: 10.1038/19783

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15175163

Title: A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology.

PubMed ID: 15175163

DOI: 10.1016/j.molcel.2004.05.006

PubMed ID: 15989967

Title: MED1/TRAP220 exists predominantly in a TRAP/Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription.

PubMed ID: 15989967

DOI: 10.1016/j.molcel.2005.05.015

Sequence Information:

Length: 877
Mass: 96793
Checksum: 15173F237A75D230
Sequence:

MCDLRRPAAG GMMDLAYVCE WEKWSKSTHC PSVPLACAWS CRNLIAFTMD LRSDDQDLTR 
MIHILDTEHP WDLHSIPSEH HEAITCLEWD QSGSRLLSAD ADGQIKCWSM ADHLANSWES 
SVGSLVEGDP IVALSWLHNG VKLALHVEKS GASSFGEKFS RVKFSPSLTL FGGKPMEGWI 
AVTVSGLVTV SLLKPSGQVL TSTESLCRLR GRVALADIAF TGGGNIVVAT ADGSSASPVQ 
FYKVCVSVVS EKCRIDTEIL PSLFMRCTTD LNRKDKFPAI THLKFLARDM SEQVLLCASS 
QTSSIVECWS LRKEGLPVNN IFQQISPVVG DKQPTILKWR ILSATNDLDR VSAVALPKLP 
ISLTNTDLKV ASDTQFYPGL GLALAFHDGS VHIVHRLSLQ TMAVFYSSAA PRPVDEPAMK 
RPRTAGPAVH LKAMQLSWTS LALVGIDSHG KLSVLRLSPS MGHPLEVGLA LRHLLFLLEY 
CMVTGYDWWD ILLHVQPSMV QSLVEKLHEE YTRQTAALQQ VLSTRILAMK ASLCKLSPCT 
VTRVCDYHTK LFLIAISSTL KSLLRPHFLN TPDKSPGDRL TEICTKITDV DIDKVMINLK 
TEEFVLDMNT LQALQQLLQW VGDFVLYLLA SLPNQGSLLR PGHSFLRDGT SLGMLRELMV 
VIRIWGLLKP SCLPVYTATS DTQDSMSLLF RLLTKLWICC RDEGPASEPD EALVDECCLL 
PSQLLIPSLD WLPASDGLVS RLQPKQPLRL QFGRAPTLPG SAATLQLDGL ARAPGQPKID 
HLRRLHLGAC PTEECKACTR CGCVTMLKSP NRTTAVKQWE QRWIKNCLAV EGRGPDACVT 
SRASEEAPAF VQLGPQSTHH SPRTPRSLDH LHPEDRP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: MED16

Associated with

Other Information

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators. PubMed ID: 10198638

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex. PubMed ID: 10235266

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334