Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 31.3225
Cell Significance Index: -12.7300 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 13.8154
Cell Significance Index: 83.4700 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 13.4277
Cell Significance Index: -12.8200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 8.5485
Cell Significance Index: 445.2800 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 7.6351
Cell Significance Index: -16.7100 - Cell Name: endocardial cell (CL0002350)
Fold Change: 4.2860
Cell Significance Index: 25.3100 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 3.4674
Cell Significance Index: 49.8700 - Cell Name: glomerular capillary endothelial cell (CL1001005)
Fold Change: 3.1728
Cell Significance Index: 11.8300 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: 2.5985
Cell Significance Index: 9.0400 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 2.2759
Cell Significance Index: 25.8600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 2.2109
Cell Significance Index: 135.5500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 2.0535
Cell Significance Index: 65.7700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.9012
Cell Significance Index: 41.1900 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 1.6206
Cell Significance Index: 39.2600 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 1.4180
Cell Significance Index: 13.4800 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 1.3273
Cell Significance Index: 23.4600 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 1.1998
Cell Significance Index: 18.0800 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 1.1515
Cell Significance Index: 7.2100 - Cell Name: endothelial cell of sinusoid (CL0002262)
Fold Change: 0.9815
Cell Significance Index: 7.2000 - Cell Name: pulmonary capillary endothelial cell (CL4028001)
Fold Change: 0.9486
Cell Significance Index: 12.9900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.7760
Cell Significance Index: 35.1800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.6928
Cell Significance Index: 131.8500 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 0.5770
Cell Significance Index: 4.5600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.3475
Cell Significance Index: 9.2800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.3200
Cell Significance Index: 31.6600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3120
Cell Significance Index: 281.7200 - Cell Name: endothelial tip cell (CL0000704)
Fold Change: 0.2308
Cell Significance Index: 0.9900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1881
Cell Significance Index: 30.6000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.1731
Cell Significance Index: 18.8300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.1124
Cell Significance Index: 6.7500 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.1000
Cell Significance Index: 2.1300 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0900
Cell Significance Index: 6.2200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0632
Cell Significance Index: 43.7000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0547
Cell Significance Index: 34.1800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0224
Cell Significance Index: 0.5600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0145
Cell Significance Index: 2.8800 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.0080
Cell Significance Index: 0.0500 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.0032
Cell Significance Index: 0.0500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0000
Cell Significance Index: 0.0000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0008
Cell Significance Index: -0.5900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0010
Cell Significance Index: -0.5700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0010
Cell Significance Index: -0.2100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0023
Cell Significance Index: -0.0800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0044
Cell Significance Index: -8.3200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0047
Cell Significance Index: -0.1400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0090
Cell Significance Index: -1.5400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0090
Cell Significance Index: -16.5500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0107
Cell Significance Index: -16.4400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0119
Cell Significance Index: -16.1800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0154
Cell Significance Index: -11.6400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0181
Cell Significance Index: -6.4900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0220
Cell Significance Index: -13.9900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0330
Cell Significance Index: -14.9700 - Cell Name: gut endothelial cell (CL0000131)
Fold Change: -0.0335
Cell Significance Index: -0.2300 - Cell Name: endothelial cell (CL0000115)
Fold Change: -0.0358
Cell Significance Index: -0.4400 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0360
Cell Significance Index: -10.3600 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: -0.0415
Cell Significance Index: -0.5700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0448
Cell Significance Index: -8.0700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0459
Cell Significance Index: -9.2100 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0695
Cell Significance Index: -8.9100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0715
Cell Significance Index: -8.1600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0736
Cell Significance Index: -9.0500 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: -0.0743
Cell Significance Index: -0.7700 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.0870
Cell Significance Index: -1.8600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0888
Cell Significance Index: -12.2000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0941
Cell Significance Index: -13.6800 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0983
Cell Significance Index: -2.0400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0985
Cell Significance Index: -11.2800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1140
Cell Significance Index: -8.7500 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1195
Cell Significance Index: -15.4400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1195
Cell Significance Index: -12.4400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1213
Cell Significance Index: -12.3900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1582
Cell Significance Index: -4.2400 - Cell Name: blood vessel endothelial cell (CL0000071)
Fold Change: -0.1588
Cell Significance Index: -1.7300 - Cell Name: lung microvascular endothelial cell (CL2000016)
Fold Change: -0.1702
Cell Significance Index: -1.4400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1744
Cell Significance Index: -11.7300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1895
Cell Significance Index: -15.0100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2046
Cell Significance Index: -15.2500 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.2180
Cell Significance Index: -9.4800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2308
Cell Significance Index: -12.9500 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: -0.2343
Cell Significance Index: -2.2300 - Cell Name: endothelial cell of artery (CL1000413)
Fold Change: -0.2363
Cell Significance Index: -2.4900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.2367
Cell Significance Index: -14.5500 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2454
Cell Significance Index: -12.4000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2684
Cell Significance Index: -11.8700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2875
Cell Significance Index: -13.5100 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.2917
Cell Significance Index: -5.9400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.2928
Cell Significance Index: -13.6500 - Cell Name: capillary endothelial cell (CL0002144)
Fold Change: -0.2984
Cell Significance Index: -3.3900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.3169
Cell Significance Index: -12.0000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.3215
Cell Significance Index: -16.7000 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.3328
Cell Significance Index: -11.6600 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: -0.3754
Cell Significance Index: -4.8500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.3823
Cell Significance Index: -10.2300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3839
Cell Significance Index: -12.5700 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3862
Cell Significance Index: -12.3000 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.3914
Cell Significance Index: -5.6100 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.3931
Cell Significance Index: -14.4300 - Cell Name: vein endothelial cell (CL0002543)
Fold Change: -0.4003
Cell Significance Index: -4.3400 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.4153
Cell Significance Index: -11.8500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1027313521
Symbol: CADH5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7627717
Title: Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin.
PubMed ID: 7627717
PubMed ID: 9219219
Title: Vascular endothelial cadherin (VE-cadherin): cloning and role in endothelial cell-cell adhesion.
PubMed ID: 9219219
PubMed ID: 10861224
Title: Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins.
PubMed ID: 10861224
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2059658
Title: Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue.
PubMed ID: 2059658
DOI: 10.1091/mbc.2.4.261
PubMed ID: 1522121
Title: A novel endothelial-specific membrane protein is a marker of cell-cell contacts.
PubMed ID: 1522121
PubMed ID: 15980433
Title: G alpha12 interaction with alphaSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier function.
PubMed ID: 15980433
PubMed ID: 16335952
Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
PubMed ID: 16335952
DOI: 10.1021/pr0502065
PubMed ID: 19139490
Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.
PubMed ID: 19139490
PubMed ID: 19996314
Title: Cell-cell contact formation governs Ca2+ signaling by TRPC4 in the vascular endothelium: evidence for a regulatory TRPC4-beta-catenin interaction.
PubMed ID: 19996314
PubMed ID: 20332120
Title: CCM1 regulates vascular-lumen organization by inducing endothelial polarity.
PubMed ID: 20332120
DOI: 10.1242/jcs.059329
PubMed ID: 21183689
Title: Endothelial reticulon-4B (Nogo-B) regulates ICAM-1-mediated leukocyte transmigration and acute inflammation.
PubMed ID: 21183689
PubMed ID: 21269602
Title: Structure and binding mechanism of vascular endothelial cadherin: a divergent classical cadherin.
PubMed ID: 21269602
PubMed ID: 27466317
Title: VE-cadherin interacts with cell polarity protein Pals1 to regulate vascular lumen formation.
PubMed ID: 27466317
Sequence Information:
- Length: 784
- Mass: 87528
- Checksum: 6DBEBFC4DA6899D1
- Sequence:
MQRLMMLLAT SGACLGLLAV AAVAAAGANP AQRDTHSLLP THRRQKRDWI WNQMHIDEEK NTSLPHHVGK IKSSVSRKNA KYLLKGEYVG KVFRVDAETG DVFAIERLDR ENISEYHLTA VIVDKDTGEN LETPSSFTIK VHDVNDNWPV FTHRLFNASV PESSAVGTSV ISVTAVDADD PTVGDHASVM YQILKGKEYF AIDNSGRIIT ITKSLDREKQ ARYEIVVEAR DAQGLRGDSG TATVLVTLQD INDNFPFFTQ TKYTFVVPED TRVGTSVGSL FVEDPDEPQN RMTKYSILRG DYQDAFTIET NPAHNEGIIK PMKPLDYEYI QQYSFIVEAT DPTIDLRYMS PPAGNRAQVI INITDVDEPP IFQQPFYHFQ LKENQKKPLI GTVLAMDPDA ARHSIGYSIR RTSDKGQFFR VTKKGDIYNE KELDREVYPW YNLTVEAKEL DSTGTPTGKE SIVQVHIEVL DENDNAPEFA KPYQPKVCEN AVHGQLVLQI SAIDKDITPR NVKFKFILNT ENNFTLTDNH DNTANITVKY GQFDREHTKV HFLPVVISDN GMPSRTGTST LTVAVCKCNE QGEFTFCEDM AAQVGVSIQA VVAILLCILT ITVITLLIFL RRRLRKQARA HGKSVPEIHE QLVTYDEEGG GEMDTTSYDV SVLNSVRRGG AKPPRPALDA RPSLYAQVQK PPRHAPGAHG GPGEMAAMIE VKKDEADHDG DGPPYDTLHI YGYEGSESIA ESLSSLGTDS SDSDVDYDFL NDWGPRFKML AELYGSDPRE ELLY
Genular Protein ID: 1213500267
Symbol: Q59EA3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 807
- Mass: 89924
- Checksum: 3A1A28EAE185E0F6
- Sequence:
TDRQSNGTET SLSPQARSVP PGKMQRLMML LATSGACLGL LAVAAVAAAG ANPAQRDTHS LLPTHRRQKR DWIWNQMHID EEKNTSLPHH VGKIKSSVSR KNAKYLLKGE YVGKVFRVDA ETGDVFAIER LDRENISEYH LTAVIVDKDT GENLETPSSF TIKVHDVNDN WPVFTHRLFN ASVPESSAVG TSVISVTAVD ADDPTVGDHA SVMYQILKGK EYFAIDNSGR IITITKSLDR EKQARYEIVV EARDAQGLRG DSGTATVLVT LQDINDNFPF FTQTKYTFVV PEDTRVGTSV GSLFVEDPDE PQNRMTKYSI LRGDYQDAFT IETNPAHNEG IIKPMKPLDY EYIQQYSFIV EATDPTIDLR YMSPPAGNRA QVIINITDVD EPPIFQQPFY HFQLKENQKK PLIGTVLAMD PDAARHSIGY SIRRTSDKGQ FFRVTKKGDI YNEKELDREV YPWYNLTVEA KELDSTGTPT GKESIVQVHI EVLDENDNAP EFAKPYQPKV CENAVHGQLV LQISAIDKDI TPRNVKFKFI LNTENNFTLT DNHDNTANIT VKYGQFDREH TKVHFLPVVI SDNGMPSRTG TSTLTVAVCK CNEQGEFTFC EDMAAQVGVS IQAVVAILLC ILTITVITLL IFLRRRLRKQ ARAHGKSVPE IHEQLVTYDE EGGGEMDTTS YDVSVLNSVR RGGAKPPRPA LDARPSLYAQ VQKPPRHAPG AHGGPGEMAA MIEVKKDEAD HDGDGPPYDT LHIYGYEGSE SIAESLSSLG TDSSDSDVDY DFLNDWGPRF KMLAELYGSD PREELLY
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.