CHAF1A | ENSG00000167670 | NCBI 10036

Details for: CHAF1A

Gene ID: 10036

Symbol: CHAF1A

Ensembl ID: ENSG00000167670

Description: chromatin assembly factor 1 subunit A

Associated with

Caf-1 complex
(GO:0033186)
Cell cycle
(GO:0007049)
Chromatin
(GO:0000785)
Chromatin binding
(GO:0003682)
Chromo shadow domain binding
(GO:0070087)
Dna repair
(GO:0006281)
Dna replication
(GO:0006260)
Dna replication-dependent chromatin assembly
(GO:0006335)
Identical protein binding
(GO:0042802)
Nucleosome assembly
(GO:0006334)
Nucleus
(GO:0005634)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Unfolded protein binding
(GO:0051082)

Other Information

Proteins

Chromatin assembly factor I p150 subunit

Genular Protein ID: 3926663281

Symbol: CAF1A_HUMAN

Name: Chromatin assembly factor I p150 subunit

UniProtKB Accession Codes:

Q13111 Q6NXG5 Q7Z7K3 Q9UJY8

Database IDs:

Citations:

PubMed ID: 11250073

Title: Genomic sequence and expression analyses of human chromatin assembly factor 1 p150 gene.

PubMed ID: 11250073

DOI: 10.1016/s0378-1119(01)00335-3

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7600578

Title: The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication.

PubMed ID: 7600578

DOI: 10.1016/s0092-8674(05)80015-7

PubMed ID: 10052459

Title: Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin.

PubMed ID: 10052459

DOI: 10.1016/s0092-8674(00)80661-3

PubMed ID: 10648606

Title: A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage.

PubMed ID: 10648606

DOI: 10.1128/mcb.20.4.1206-1218.2000

PubMed ID: 10893180

Title: CAF-1 and the inheritance of chromatin states: at the crossroads of DNA replication and repair.

PubMed ID: 10893180

DOI: 10.1242/jcs.113.15.2647

PubMed ID: 11296234

Title: Dimerization of the largest subunit of chromatin assembly factor 1: importance in vitro and during Xenopus early development.

PubMed ID: 11296234

DOI: 10.1093/emboj/20.8.2015

PubMed ID: 12697822

Title: The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1.

PubMed ID: 12697822

DOI: 10.1128/mcb.23.9.3226-3236.2003

PubMed ID: 15327775

Title: Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly.

PubMed ID: 15327775

DOI: 10.1016/j.molcel.2004.06.043

PubMed ID: 30849389

Title: Retraction Notice to: Methyl-CpG Binding Protein MBD1 Couples Histone H3 Methylation at Lysine 9 by SETDB1 to DNA Replication and Chromatin Assembly.

PubMed ID: 30849389

DOI: 10.1016/j.molcel.2019.02.023

PubMed ID: 15882967

Title: The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain.

PubMed ID: 15882967

DOI: 10.1016/j.bbrc.2005.04.016

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20562864

Title: Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.

PubMed ID: 20562864

DOI: 10.1038/ncb2075

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 33857403

Title: DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network.

PubMed ID: 33857403

DOI: 10.1016/j.molcel.2021.03.041

Sequence Information:

Length: 956
Mass: 106910
Checksum: 90617F8FE8DB7FD0
Sequence:

MLEELECGAP GARGAATAMD CKDRPAFPVK KLIQARLPFK RLNLVPKGKA DDMSDDQGTS 
VQSKSPDLEA SLDTLENNCH VGSDIDFRPK LVNGKGPLDN FLRNRIETSI GQSTVIIDLT 
EDSNEQPDSL VDHNKLNSEA SPSREAINGQ REDTGDQQGL LKAIQNDKLA FPGETLSDIP 
CKTEEEGVGC GGAGRRGDSQ ECSPRSCPEL TSGPRMCPRK EQDSWSEAGG ILFKGKVPMV 
VLQDILAVRP PQIKSLPATP QGKNMTPESE VLESFPEEDS VLSHSSLSSP SSTSSPEGPP 
APPKQHSSTS PFPTSTPLRR ITKKFVKGST EKNKLRLQRD QERLGKQLKL RAEREEKEKL 
KEEAKRAKEE AKKKKEEEKE LKEKERREKR EKDEKEKAEK QRLKEERRKE RQEALEAKLE 
EKRKKEEEKR LREEEKRIKA EKAEITRFFQ KPKTPQAPKT LAGSCGKFAP FEIKEHMVLA 
PRRRTAFHPD LCSQLDQLLQ QQSGEFSFLK DLKGRQPLRS GPTHVSTRNA DIFNSDVVIV 
ERGKGDGVPE RRKFGRMKLL QFCENHRPAY WGTWNKKTAL IRARDPWAQD TKLLDYEVDS 
DEEWEEEEPG ESLSHSEGDD DDDMGEDEDE DDGFFVPHGY LSEDEGVTEE CADPENHKVR 
QKLKAKEWDE FLAKGKRFRV LQPVKIGCVW AADRDCAGDD LKVLQQFAAC FLETLPAQEE 
QTPKASKRER RDEQILAQLL PLLHGNVNGS KVIIREFQEH CRRGLLSNHT GSPRSPSTTY 
LHTPTPSEDA AIPSKSRLKR LISENSVYEK RPDFRMCWYV HPQVLQSFQQ EHLPVPCQWS 
YVTSVPSAPK EDSGSVPSTG PSQGTPISLK RKSAGSMCIT QFMKKRRHDG QIGAEDMDGF 
QADTEEEEEE EGDCMIVDVP DAAEVQAPCG AASGAGGGVG VDTGKATLTA SPLGAS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CHAF1A

Associated with

Other Information

Genomic sequence and expression analyses of human chromatin assembly factor 1 p150 gene. PubMed ID: 11250073

The DNA sequence and biology of human chromosome 19. PubMed ID: 15057824

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication. PubMed ID: 7600578

Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin. PubMed ID: 10052459

A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage. PubMed ID: 10648606

CAF-1 and the inheritance of chromatin states: at the crossroads of DNA replication and repair. PubMed ID: 10893180

Dimerization of the largest subunit of chromatin assembly factor 1: importance in vitro and during Xenopus early development. PubMed ID: 11296234

The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1. PubMed ID: 12697822

Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly. PubMed ID: 15327775

Retraction Notice to: Methyl-CpG Binding Protein MBD1 Couples Histone H3 Methylation at Lysine 9 by SETDB1 to DNA Replication and Chromatin Assembly. PubMed ID: 30849389

The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain. PubMed ID: 15882967

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. PubMed ID: 17081983

Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. PubMed ID: 18220336

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. PubMed ID: 20562864

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

Uncovering global SUMOylation signaling networks in a site-specific manner. PubMed ID: 25218447

Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli. PubMed ID: 25114211

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. PubMed ID: 28112733

DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network. PubMed ID: 33857403