Details for: PARP3
Associated with
Other Information
Genular Protein ID: 517032857
Symbol: PARP3_HUMAN
Name: IRT1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10329013
Title: A human poly(ADP-ribose) polymerase gene family (ADPRTL): cDNA cloning of two novel poly(ADP-ribose) polymerase homologues.
PubMed ID: 10329013
PubMed ID: 12640039
Title: PARP-3 localizes preferentially to the daughter centriole and interferes with the G1/S cell cycle progression.
PubMed ID: 12640039
DOI: 10.1242/jcs.00341
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16924674
Title: PARP-3 associates with polycomb group bodies and with components of the DNA damage repair machinery.
PubMed ID: 16924674
DOI: 10.1002/jcb.21051
PubMed ID: 20106667
Title: Toward a unified nomenclature for mammalian ADP-ribosyltransferases.
PubMed ID: 20106667
PubMed ID: 20064938
Title: PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA.
PubMed ID: 20064938
PubMed ID: 21211721
Title: PARP-3 and APLF function together to accelerate nonhomologous end-joining.
PubMed ID: 21211721
PubMed ID: 21270334
Title: Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression.
PubMed ID: 21270334
PubMed ID: 25043379
Title: Family-wide analysis of poly(ADP-ribose) polymerase activity.
PubMed ID: 25043379
DOI: 10.1038/ncomms5426
PubMed ID: 24598253
Title: PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.
PubMed ID: 24598253
DOI: 10.1093/nar/gku174
PubMed ID: 27530147
Title: PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2).
PubMed ID: 27530147
DOI: 10.1038/ncomms12404
PubMed ID: 28447610
Title: PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.
PubMed ID: 28447610
DOI: 10.1038/ncomms15110
PubMed ID: 29361132
Title: Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: new insights into DNA ADP-ribosylation.
PubMed ID: 29361132
DOI: 10.1093/nar/gkx1318
PubMed ID: 29520010
PubMed ID: 19354255
Title: Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3.
PubMed ID: 19354255
DOI: 10.1021/jm900052j
PubMed ID: 23742272
Title: PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3.
PubMed ID: 23742272
DOI: 10.1021/cb4002014
PubMed ID: 24188023
Title: Chemical probes to study ADP-ribosylation: synthesis and biochemical evaluation of inhibitors of the human ADP-ribosyltransferase ARTD3/PARP3.
PubMed ID: 24188023
DOI: 10.1021/jm401394u
Sequence Information:
- Length: 533
- Mass: 60089
- Checksum: 6296A0E439CC7767
- Sequence:
MAPKPKPWVQ TEGPEKKKGR QAGREEDPFR STAEALKAIP AEKRIIRVDP TCPLSSNPGT QVYEDYNCTL NQTNIENNNN KFYIIQLLQD SNRFFTCWNR WGRVGEVGQS KINHFTRLED AKKDFEKKFR EKTKNNWAER DHFVSHPGKY TLIEVQAEDE AQEAVVKVDR GPVRTVTKRV QPCSLDPATQ KLITNIFSKE MFKNTMALMD LDVKKMPLGK LSKQQIARGF EALEALEEAL KGPTDGGQSL EELSSHFYTV IPHNFGHSQP PPINSPELLQ AKKDMLLVLA DIELAQALQA VSEQEKTVEE VPHPLDRDYQ LLKCQLQLLD SGAPEYKVIQ TYLEQTGSNH RCPTLQHIWK VNQEGEEDRF QAHSKLGNRK LLWHGTNMAV VAAILTSGLR IMPHSGGRVG KGIYFASENS KSAGYVIGMK CGAHHVGYMF LGEVALGREH HINTDNPSLK SPPPGFDSVI ARGHTEPDPT QDTELELDGQ QVVVPQGQPV PCPEFSSSTF SQSEYLIYQE SQCRLRYLLE VHL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.