Details for: TOM1

Gene ID: 10043

Symbol: TOM1

Ensembl ID: ENSG00000100284

Description: target of myb1 membrane trafficking protein

Associated with

Other Information

Genular Protein ID: 1440674088

Symbol: TOM1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10329004

Title: TOM1 genes map to human chromosome 22q13.1 and mouse chromosome 8C1 and encode proteins similar to the endosomal proteins HGS and STAM.

PubMed ID: 10329004

DOI: 10.1006/geno.1998.5739

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14563850

Title: Tom1, a VHS domain-containing protein, interacts with tollip, ubiquitin, and clathrin.

PubMed ID: 14563850

DOI: 10.1074/jbc.m306740200

PubMed ID: 14613930

Title: Endofin recruits TOM1 to endosomes.

PubMed ID: 14613930

DOI: 10.1074/jbc.m311228200

PubMed ID: 15047686

Title: Tollip and Tom1 form a complex and recruit ubiquitin-conjugated proteins onto early endosomes.

PubMed ID: 15047686

DOI: 10.1074/jbc.m400059200

PubMed ID: 15657082

Title: Endofin recruits clathrin to early endosomes via TOM1.

PubMed ID: 15657082

DOI: 10.1242/jcs.01628

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 23023224

Title: Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome.

PubMed ID: 23023224

DOI: 10.1038/ncb2589

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25588840

Title: TOM1 is a PI5P effector involved in the regulation of endosomal maturation.

PubMed ID: 25588840

DOI: 10.1242/jcs.166314

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 10985773

Title: Structure of the VHS domain of human Tom1 (target of myb 1): insights into interactions with proteins and membranes.

PubMed ID: 10985773

DOI: 10.1021/bi0013546

PubMed ID: 16199040

Title: Structural basis for recognition of ubiquitinated cargo by Tom1-GAT domain.

PubMed ID: 16199040

DOI: 10.1016/j.febslet.2005.08.076

PubMed ID: 26320582

Title: Tom1 Modulates Binding of Tollip to Phosphatidylinositol 3-Phosphate via a Coupled Folding and Binding Mechanism.

PubMed ID: 26320582

DOI: 10.1016/j.str.2015.07.017

PubMed ID: 26977434

Title: Structure of the GAT domain of the endosomal adapter protein Tom1.

PubMed ID: 26977434

DOI: 10.1016/j.dib.2016.02.042

PubMed ID: 31371777

Title: Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering.

PubMed ID: 31371777

DOI: 10.1038/s41467-019-11481-6

PubMed ID: 31263572

Title: Dominant TOM1 mutation associated with combined immunodeficiency and autoimmune disease.

PubMed ID: 31263572

DOI: 10.1038/s41525-019-0088-5

Sequence Information:

  • Length: 492
  • Mass: 53818
  • Checksum: C7D77B5669476242
  • Sequence:
  • MDFLLGNPFS SPVGQRIEKA TDGSLQSEDW ALNMEICDII NETEEGPKDA LRAVKKRIVG 
    NKNFHEVMLA LTVLETCVKN CGHRFHVLVA SQDFVESVLV RTILPKNNPP TIVHDKVLNL 
    IQSWADAFRS SPDLTGVVTI YEDLRRKGLE FPMTDLDMLS PIHTPQRTVF NSETQSGQDS 
    VGTDSSQQED SGQHAAPLPA PPILSGDTPI APTPEQIGKL RSELEMVSGN VRVMSEMLTE 
    LVPTQAEPAD LELLQELNRT CRAMQQRVLE LIPQIANEQL TEELLIVNDN LNNVFLRHER 
    FERFRTGQTT KAPSEAEPAA DLIDMGPDPA ATGNLSSQLA GMNLGSSSVR AGLQSLEASG 
    RLEDEFDMFA LTRGSSLADQ RKEVKYEAPQ ATDGLAGALD ARQQSTGAIP VTQACLMEDI 
    EQWLSTDVGN DAEEPKGVTS EEFDKFLEER AKAADRLPNL SSPSAEGPPG PPSGPAPRKK 
    TQEKDDDMLF AL

Genular Protein ID: 3985177214

Symbol: B3KUF5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 229
  • Mass: 24740
  • Checksum: 1DE3B62A95C5399C
  • Sequence:
  • MQQRVLELIP QIANEQLTEE LLIVNDNLNN VFLRHERFER FRTGQTTKAP SEAEPAADLI 
    DMGPDPAATG NLSSQLAGMN LGSSSVRAGL QSLEASGRLE DGFDMFALTR GSSLADQRKE 
    VKYEAPQATD GLAGALDARQ QSTGAIPVTQ ACLMEDIEQW LSTDVGNDAE EPKGVTSEEF 
    DKFLEERAKA ADRLPNLSSP SAEGPPGPPS GPAPRKKTQE KDDDMLFAL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.