Details for: ABCC5

Gene ID: 10057

Symbol: ABCC5

Ensembl ID: ENSG00000114770

Description: ATP binding cassette subfamily C member 5

Associated with

Other Information

Genular Protein ID: 776680577

Symbol: MRP5_HUMAN

Name: ATP-binding cassette sub-family C member 5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9827529

Title: Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins.

PubMed ID: 9827529

DOI: 10.1093/jnci/90.22.1735

PubMed ID: 10438534

Title: pABC11 (also known as MOAT-C and MRP5), a member of the ABC family of proteins, has anion transporter activity but does not confer multidrug resistance when overexpressed in human embryonic kidney 293 cells.

PubMed ID: 10438534

DOI: 10.1074/jbc.274.33.23541

PubMed ID: 10721709

Title: Detailed structural analysis on both human MRP5 and mouse mrp5 transcripts.

PubMed ID: 10721709

DOI: 10.1016/s0378-1119(99)00529-6

PubMed ID: 10840050

Title: Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs.

PubMed ID: 10840050

DOI: 10.1073/pnas.120159197

PubMed ID: 17521428

Title: Three novel ABCC5 splice variants in human retina and their role as regulators of ABCC5 gene expression.

PubMed ID: 17521428

DOI: 10.1186/1471-2199-8-42

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9325169

Title: cDNA cloning of a short type of multidrug resistance protein homologue, SMRP, from a human lung cancer cell line.

PubMed ID: 9325169

DOI: 10.1006/bbrc.1997.7346

PubMed ID: 9270026

Title: Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.

PubMed ID: 9270026

PubMed ID: 10893247

Title: The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides.

PubMed ID: 10893247

DOI: 10.1074/jbc.m005463200

PubMed ID: 12435799

Title: Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells.

PubMed ID: 12435799

DOI: 10.1124/mol.62.6.1321

PubMed ID: 12695538

Title: Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5.

PubMed ID: 12695538

DOI: 10.1124/mol.63.5.1094

PubMed ID: 12637526

Title: Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells.

PubMed ID: 12637526

DOI: 10.1074/jbc.m212723200

PubMed ID: 15501592

Title: Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain.

PubMed ID: 15501592

DOI: 10.1016/j.neuroscience.2004.07.051

PubMed ID: 15899835

Title: The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates.

PubMed ID: 15899835

DOI: 10.1158/0008-5472.can-04-2810

PubMed ID: 17229149

Title: cGMP transport by vesicles from human and mouse erythrocytes.

PubMed ID: 17229149

DOI: 10.1111/j.1742-4658.2006.05591.x

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24836561

Title: Control of metazoan heme homeostasis by a conserved multidrug resistance protein.

PubMed ID: 24836561

DOI: 10.1016/j.cmet.2014.03.030

PubMed ID: 26515061

Title: ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs.

PubMed ID: 26515061

DOI: 10.1074/jbc.m115.692103

PubMed ID: 25964343

Title: N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids.

PubMed ID: 25964343

DOI: 10.1073/pnas.1424638112

Sequence Information:

  • Length: 1437
  • Mass: 160660
  • Checksum: 00558076B3BB4C00
  • Sequence:
  • MKDIDIGKEY IIPSPGYRSV RERTSTSGTH RDREDSKFRR TRPLECQDAL ETAARAEGLS 
    LDASMHSQLR ILDEEHPKGK YHHGLSALKP IRTTSKHQHP VDNAGLFSCM TFSWLSSLAR 
    VAHKKGELSM EDVWSLSKHE SSDVNCRRLE RLWQEELNEV GPDAASLRRV VWIFCRTRLI 
    LSIVCLMITQ LAGFSGPAFM VKHLLEYTQA TESNLQYSLL LVLGLLLTEI VRSWSLALTW 
    ALNYRTGVRL RGAILTMAFK KILKLKNIKE KSLGELINIC SNDGQRMFEA AAVGSLLAGG 
    PVVAILGMIY NVIILGPTGF LGSAVFILFY PAMMFASRLT AYFRRKCVAA TDERVQKMNE 
    VLTYIKFIKM YAWVKAFSQS VQKIREEERR ILEKAGYFQS ITVGVAPIVV VIASVVTFSV 
    HMTLGFDLTA AQAFTVVTVF NSMTFALKVT PFSVKSLSEA SVAVDRFKSL FLMEEVHMIK 
    NKPASPHIKI EMKNATLAWD SSHSSIQNSP KLTPKMKKDK RASRGKKEKV RQLQRTEHQA 
    VLAEQKGHLL LDSDERPSPE EEEGKHIHLG HLRLQRTLHS IDLEIQEGKL VGICGSVGSG 
    KTSLISAILG QMTLLEGSIA ISGTFAYVAQ QAWILNATLR DNILFGKEYD EERYNSVLNS 
    CCLRPDLAIL PSSDLTEIGE RGANLSGGQR QRISLARALY SDRSIYILDD PLSALDAHVG 
    NHIFNSAIRK HLKSKTVLFV THQLQYLVDC DEVIFMKEGC ITERGTHEEL MNLNGDYATI 
    FNNLLLGETP PVEINSKKET SGSQKKSQDK GPKTGSVKKE KAVKPEEGQL VQLEEKGQGS 
    VPWSVYGVYI QAAGGPLAFL VIMALFMLNV GSTAFSTWWL SYWIKQGSGN TTVTRGNETS 
    VSDSMKDNPH MQYYASIYAL SMAVMLILKA IRGVVFVKGT LRASSRLHDE LFRRILRSPM 
    KFFDTTPTGR ILNRFSKDMD EVDVRLPFQA EMFIQNVILV FFCVGMIAGV FPWFLVAVGP 
    LVILFSVLHI VSRVLIRELK RLDNITQSPF LSHITSSIQG LATIHAYNKG QEFLHRYQEL 
    LDDNQAPFFL FTCAMRWLAV RLDLISIALI TTTGLMIVLM HGQIPPAYAG LAISYAVQLT 
    GLFQFTVRLA SETEARFTSV ERINHYIKTL SLEAPARIKN KAPSPDWPQE GEVTFENAEM 
    RYRENLPLVL KKVSFTIKPK EKIGIVGRTG SGKSSLGMAL FRLVELSGGC IKIDGVRISD 
    IGLADLRSKL SIIPQEPVLF SGTVRSNLDP FNQYTEDQIW DALERTHMKE CIAQLPLKLE 
    SEVMENGDNF SVGERQLLCI ARALLRHCKI LILDEATAAM DTETDLLIQE TIREAFADCT 
    MLTIAHRLHT VLGSDRIMVL AQGQVVEFDT PSVLLSNDSS RFYAMFAAAE NKVAVKG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.