Details for: ABCC9

Gene ID: 10060

Symbol: ABCC9

Ensembl ID: ENSG00000069431

Description: ATP binding cassette subfamily C member 9

Associated with

Other Information

Genular Protein ID: 2084951737

Symbol: ABCC9_HUMAN

Name: ATP-binding cassette sub-family C member 9

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9457174

Title: Toward understanding the assembly and structure of KATP channels.

PubMed ID: 9457174

DOI: 10.1152/physrev.1998.78.1.227

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 9831708

Title: Reconstituted human cardiac KATP channels: functional identity with the native channels from the sarcolemma of human ventricular cells.

PubMed ID: 9831708

DOI: 10.1161/01.res.83.11.1132

PubMed ID: 22105623

Title: A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila.

PubMed ID: 22105623

DOI: 10.1038/mp.2011.142

PubMed ID: 15034580

Title: ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating.

PubMed ID: 15034580

DOI: 10.1038/ng1329

PubMed ID: 17245405

Title: KATP channel mutation confers risk for vein of Marshall adrenergic atrial fibrillation.

PubMed ID: 17245405

DOI: 10.1038/ncpcardio0792

PubMed ID: 22608503

Title: Cantu syndrome is caused by mutations in ABCC9.

PubMed ID: 22608503

DOI: 10.1016/j.ajhg.2012.04.014

PubMed ID: 22610116

Title: Dominant missense mutations in ABCC9 cause Cantu syndrome.

PubMed ID: 22610116

DOI: 10.1038/ng.2324

PubMed ID: 26621776

Title: Differential mechanisms of Cantu syndrome-associated gain of function mutations in the ABCC9 (SUR2) subunit of the KATP channel.

PubMed ID: 26621776

DOI: 10.1085/jgp.201511495

PubMed ID: 31303265

Title: De Novo Variants Disturbing the Transactivation Capacity of POU3F3 Cause a Characteristic Neurodevelopmental Disorder.

PubMed ID: 31303265

DOI: 10.1016/j.ajhg.2019.06.007

PubMed ID: 31575858

Title: ABCC9-related Intellectual disability Myopathy Syndrome is a KATP channelopathy with loss-of-function mutations in ABCC9.

PubMed ID: 31575858

DOI: 10.1038/s41467-019-12428-7

Sequence Information:

  • Length: 1549
  • Mass: 174223
  • Checksum: 55508C9343AB1218
  • Sequence:
  • MSLSFCGNNI SSYNINDGVL QNSCFVDALN LVPHVFLLFI TFPILFIGWG SQSSKVQIHH 
    NTWLHFPGHN LRWILTFALL FVHVCEIAEG IVSDSRRESR HLHLFMPAVM GFVATTTSIV 
    YYHNIETSNF PKLLLALFLY WVMAFITKTI KLVKYCQSGL DISNLRFCIT GMMVILNGLL 
    MAVEINVIRV RRYVFFMNPQ KVKPPEDLQD LGVRFLQPFV NLLSKATYWW MNTLIISAHK 
    KPIDLKAIGK LPIAMRAVTN YVCLKDAYEE QKKKVADHPN RTPSIWLAMY RAFGRPILLS 
    STFRYLADLL GFAGPLCISG IVQRVNETQN GTNNTTGISE TLSSKEFLEN AYVLAVLLFL 
    ALILQRTFLQ ASYYVTIETG INLRGALLAM IYNKILRLST SNLSMGEMTL GQINNLVAIE 
    TNQLMWFLFL CPNLWAMPVQ IIMGVILLYN LLGSSALVGA AVIVLLAPIQ YFIATKLAEA 
    QKSTLDYSTE RLKKTNEILK GIKLLKLYAW EHIFCKSVEE TRMKELSSLK TFALYTSLSI 
    FMNAAIPIAA VLATFVTHAY ASGNNLKPAE AFASLSLFHI LVTPLFLLST VVRFAVKAII 
    SVQKLNEFLL SDEIGDDSWR TGESSLPFES CKKHTGVQPK TINRKQPGRY HLDSYEQSTR 
    RLRPAETEDI AIKVTNGYFS WGSGLATLSN IDIRIPTGQL TMIVGQVGCG KSSLLLAILG 
    EMQTLEGKVH WSNVNESEPS FEATRSRNRY SVAYAAQKPW LLNATVEENI TFGSPFNKQR 
    YKAVTDACSL QPDIDLLPFG DQTEIGERGI NLSGGQRQRI CVARALYQNT NIVFLDDPFS 
    ALDIHLSDHL MQEGILKFLQ DDKRTLVLVT HKLQYLTHAD WIIAMKDGSV LREGTLKDIQ 
    TKDVELYEHW KTLMNRQDQE LEKDMEADQT TLERKTLRRA MYSREAKAQM EDEDEEEEEE 
    EDEDDNMSTV MRLRTKMPWK TCWRYLTSGG FFLLILMIFS KLLKHSVIVA IDYWLATWTS 
    EYSINNTGKA DQTYYVAGFS ILCGAGIFLC LVTSLTVEWM GLTAAKNLHH NLLNKIILGP 
    IRFFDTTPLG LILNRFSADT NIIDQHIPPT LESLTRSTLL CLSAIGMISY ATPVFLVALL 
    PLGVAFYFIQ KYFRVASKDL QELDDSTQLP LLCHFSETAE GLTTIRAFRH ETRFKQRMLE 
    LTDTNNIAYL FLSAANRWLE VRTDYLGACI VLTASIASIS GSSNSGLVGL GLLYALTITN 
    YLNWVVRNLA DLEVQMGAVK KVNSFLTMES ENYEGTMDPS QVPEHWPQEG EIKIHDLCVR 
    YENNLKPVLK HVKAYIKPGQ KVGICGRTGS GKSSLSLAFF RMVDIFDGKI VIDGIDISKL 
    PLHTLRSRLS IILQDPILFS GSIRFNLDPE CKCTDDRLWE ALEIAQLKNM VKSLPGGLDA 
    VVTEGGENFS VGQRQLFCLA RAFVRKSSIL IMDEATASID MATENILQKV VMTAFADRTV 
    VTIAHRVSSI MDAGLVLVFS EGILVECDTV PNLLAHKNGL FSTLVMTNK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.