Details for: CERT1

Gene ID: 10087

Symbol: CERT1

Ensembl ID: ENSG00000113163

Description: ceramide transporter 1

Associated with

Other Information

Genular Protein ID: 3589358786

Symbol: CERT_HUMAN

Name: START domain-containing protein 11

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10212244

Title: Characterization of a novel type of serine/threonine kinase that specifically phosphorylates the human goodpasture antigen.

PubMed ID: 10212244

DOI: 10.1074/jbc.274.18.12642

PubMed ID: 11007769

Title: Goodpasture antigen-binding protein, the kinase that phosphorylates the Goodpasture antigen, is an alternatively spliced variant implicated in autoimmune pathogenesis.

PubMed ID: 11007769

DOI: 10.1074/jbc.m002769200

PubMed ID: 14685229

Title: Molecular machinery for non-vesicular trafficking of ceramide.

PubMed ID: 14685229

DOI: 10.1038/nature02188

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16895911

Title: Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT.

PubMed ID: 16895911

DOI: 10.1074/jbc.m605032200

PubMed ID: 17591919

Title: Regulation of secretory transport by protein kinase D-mediated phosphorylation of the ceramide transfer protein.

PubMed ID: 17591919

DOI: 10.1083/jcb.200612017

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19005213

Title: Casein kinase I{gamma}2 down-regulates trafficking of ceramide in the synthesis of sphingomyelin.

PubMed ID: 19005213

DOI: 10.1091/mbc.e08-07-0669

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25533962

Title: Large-scale discovery of novel genetic causes of developmental disorders.

PubMed ID: 25533962

DOI: 10.1038/nature14135

PubMed ID: 29858488

Title: Identification of MOSPD2, a novel scaffold for endoplasmic reticulum membrane contact sites.

PubMed ID: 29858488

DOI: 10.15252/embr.201745453

PubMed ID: 18184806

Title: Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide.

PubMed ID: 18184806

DOI: 10.1073/pnas.0709191105

PubMed ID: 20036255

Title: Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer.

PubMed ID: 20036255

DOI: 10.1016/j.jmb.2009.12.029

PubMed ID: 23033978

Title: Diagnostic exome sequencing in persons with severe intellectual disability.

PubMed ID: 23033978

DOI: 10.1056/nejmoa1206524

PubMed ID: 25356899

Title: De novo mutations in moderate or severe intellectual disability.

PubMed ID: 25356899

DOI: 10.1371/journal.pgen.1004772

Sequence Information:

  • Length: 624
  • Mass: 70835
  • Checksum: A125162492AC5A0E
  • Sequence:
  • MSDNQSWNSS GSEEDPETES GPPVERCGVL SKWTNYIHGW QDRWVVLKNN ALSYYKSEDE 
    TEYGCRGSIC LSKAVITPHD FDECRFDISV NDSVWYLRAQ DPDHRQQWID AIEQHKTESG 
    YGSESSLRRH GSMVSLVSGA SGYSATSTSS FKKGHSLREK LAEMETFRDI LCRQVDTLQK 
    YFDACADAVS KDELQRDKVV EDDEDDFPTT RSDGDFLHST NGNKEKLFPH VTPKGINGID 
    FKGEAITFKA TTAGILATLS HCIELMVKRE DSWQKRLDKE TEKKRRTEEA YKNAMTELKK 
    KSHFGGPDYE EGPNSLINEE EFFDAVEAAL DRQDKIEEQS QSEKVRLHWP TSLPSGDAFS 
    SVGTHRFVQK PYSRSSSMSS IDLVSASDDV HRFSSQVEEM VQNHMTYSLQ DVGGDANWQL 
    VVEEGEMKVY RREVEENGIV LDPLKATHAV KGVTGHEVCN YFWNVDVRND WETTIENFHV 
    VETLADNAII IYQTHKRVWP ASQRDVLYLS VIRKIPALTE NDPETWIVCN FSVDHDSAPL 
    NNRCVRAKIN VAMICQTLVS PPEGNQEISR DNILCKITYV ANVNPGGWAP ASVLRAVAKR 
    EYPKFLKRFT SYVQEKTAGK PILF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.