Details for: TSFM

Gene ID: 10102

Symbol: TSFM

Ensembl ID: ENSG00000123297

Description: Ts translation elongation factor, mitochondrial

Associated with

Other Information

Genular Protein ID: 648649329

Symbol: EFTS_HUMAN

Name: N/A

UniProtKB Accession Codes:

P43897 B4E391 F5H2T7 Q561V7 Q8TBC2 Q9UQK0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 EPD 1 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 9 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HAMAP 1 HAMAP-Rule 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7615523

Title: Cloning and expression of mitochondrial translational elongation factor Ts from bovine and human liver.

PubMed ID: 7615523

DOI: 10.1074/jbc.270.29.17243

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 17033963

Title: Distinct clinical phenotypes associated with a mutation in the mitochondrial translation elongation factor EFTs.

PubMed ID: 17033963

DOI: 10.1086/508434

PubMed ID: 22499341

Title: Genomic analysis of mitochondrial diseases in a consanguineous population reveals novel candidate disease genes.

PubMed ID: 22499341

DOI: 10.1136/jmedgenet-2012-100836

PubMed ID: 27677415

Title: Molecular-genetic characterization and rescue of a TSFM mutation causing childhood-onset ataxia and nonobstructive cardiomyopathy.

PubMed ID: 27677415

DOI: 10.1038/ejhg.2016.124

Sequence Information:

  • Length: 325
  • Mass: 35391
  • Checksum: 671645764A9CB31C
  • Sequence:
    • MSLLRSLRVF LVARTGSYPA GSLLRQSPQP RHTFYAGPRL SASASSKELL MKLRRKTGYS 
FVNCKKALET CGGDLKQAEI WLHKEAQKEG WSKAAKLQGR KTKEGLIGLL QEGNTTVLVE 
VNCETDFVSR NLKFQLLVQQ VALGTMMHCQ TLKDQPSAYS KGFLNSSELS GLPAGPDREG 
SLKDQLALAI GKLGENMILK RAAWVKVPSG FYVGSYVHGA MQSPSLHKLV LGKYGALVIC 
ETSEQKTNLE DVGRRLGQHV VGMAPLSVGS LDDEPGGEAE TKMLSQPYLL DPSITLGQYV 
QPQGVSVVDF VRFECGEGEE AAETE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.