Details for: CDH12P2

Gene ID: 1011

Symbol: CDH12P2

Ensembl ID: ENSG00000249230

Description: cadherin 12 pseudogene 2

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 0.0793
    Cell Significance Index: 0.9200
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 0.0221
    Cell Significance Index: 0.2000
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.0115
    Cell Significance Index: 0.1400
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0076
    Cell Significance Index: -0.0800
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0119
    Cell Significance Index: -0.1300
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0160
    Cell Significance Index: -0.2000
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0193
    Cell Significance Index: -0.2200
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0215
    Cell Significance Index: -0.2400
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.0219
    Cell Significance Index: -0.2900
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.0233
    Cell Significance Index: -0.2700
  • Cell Name: B cell (CL0000236)
    Fold Change: -0.0237
    Cell Significance Index: -0.2800
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0244
    Cell Significance Index: -0.2700
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.0251
    Cell Significance Index: -0.3300
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: -0.0271
    Cell Significance Index: -0.3300
  • Cell Name: mast cell (CL0000097)
    Fold Change: -0.0274
    Cell Significance Index: -0.3600
  • Cell Name: plasma cell (CL0000786)
    Fold Change: -0.0286
    Cell Significance Index: -0.3200
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.0288
    Cell Significance Index: -0.3500
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.0290
    Cell Significance Index: -0.2800
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: -0.0298
    Cell Significance Index: -0.3300
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.0299
    Cell Significance Index: -0.2800
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: -0.0299
    Cell Significance Index: -0.3400
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.0301
    Cell Significance Index: -0.3300
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: -0.0304
    Cell Significance Index: -0.3300
  • Cell Name: alveolar adventitial fibroblast (CL4028006)
    Fold Change: -0.0315
    Cell Significance Index: -0.3500
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: -0.0320
    Cell Significance Index: -0.2800
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.0328
    Cell Significance Index: -0.3100
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: -0.0338
    Cell Significance Index: -0.3100
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0362
    Cell Significance Index: -0.4300
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.0391
    Cell Significance Index: -0.5100
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.0399
    Cell Significance Index: -0.3300
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.0449
    Cell Significance Index: -0.5000
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: -0.0466
    Cell Significance Index: -0.5000
  • Cell Name: respiratory basal cell (CL0002633)
    Fold Change: -0.0498
    Cell Significance Index: -0.4900
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: -0.0508
    Cell Significance Index: -0.5400
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: -0.0541
    Cell Significance Index: -0.5800
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: -0.0557
    Cell Significance Index: -0.5800
  • Cell Name: alveolar type 1 fibroblast cell (CL4028004)
    Fold Change: -0.0645
    Cell Significance Index: -0.6800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Pseudogene status**: CDH12P2 is a pseudogene, meaning it lacks the ability to encode a functional protein. This suggests that its primary function may be to regulate gene expression or influence cellular behavior through alternative mechanisms. 2. **Widespread expression**: CDH12P2 is expressed in a variety of cell types, including those involved in immune responses, neural function, and tissue maintenance. 3. **Evolutionary conservation**: The presence of CDH12P2 in multiple species suggests that it may have a conserved function across different organisms. **Pathways and Functions:** 1. **Cell-cell adhesion**: Although CDH12P2 is a pseudogene, it may still play a role in regulating cell-cell adhesion, particularly in the context of immune responses. 2. **Signaling pathways**: CDH12P2 may influence signaling pathways involved in cell proliferation, differentiation, and survival, such as the Wnt/β-catenin pathway. 3. **Regulation of gene expression**: CDH12P2 may act as a transcriptional regulator, influencing the expression of genes involved in immune responses, neural function, and tissue maintenance. 4. **Epigenetic regulation**: CDH12P2 may also participate in epigenetic regulation, influencing the methylation status of DNA or histone modification. **Clinical Significance:** 1. **Immune system disorders**: Alterations in CDH12P2 expression may contribute to immune system disorders, such as autoimmune diseases or cancer. 2. **Neurological disorders**: Changes in CDH12P2 expression may be associated with neurological disorders, such as Alzheimer's disease, Parkinson's disease, or multiple sclerosis. 3. **Cancer**: CDH12P2 may play a role in cancer development and progression, particularly in the context of immune evasion. 4. **Regenerative medicine**: Understanding the function of CDH12P2 may lead to the development of novel therapeutic strategies for tissue repair and regeneration. In conclusion, while the functional significance of CDH12P2 remains unclear, its widespread expression in various cell types suggests that it may play a role in regulating immune responses, neural function, and tissue maintenance. Further research is needed to uncover the molecular mechanisms underlying the function of CDH12P2 and its potential clinical applications.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.