Details for: SGK2

Gene ID: 10110

Symbol: SGK2

Ensembl ID: ENSG00000101049

Description: serum/glucocorticoid regulated kinase 2

Associated with

Other Information

Genular Protein ID: 4126703019

Symbol: SGK2_HUMAN

Name: Serine/threonine-protein kinase Sgk2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10548550

Title: Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase.

PubMed ID: 10548550

DOI: 10.1042/bj3440189

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12590200

Title: Activation of Na+/K+-ATPase by the serum and glucocorticoid-dependent kinase isoforms.

PubMed ID: 12590200

DOI: 10.1159/000068699

PubMed ID: 12397388

Title: K(+) channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK.

PubMed ID: 12397388

DOI: 10.1007/s00424-002-0873-2

PubMed ID: 12634932

Title: Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms.

PubMed ID: 12634932

DOI: 10.1007/s00424-002-0982-y

PubMed ID: 12632189

Title: The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel alpha,beta,gamma-ENaC.

PubMed ID: 12632189

DOI: 10.1007/s00424-002-0993-8

PubMed ID: 15040001

Title: Regulation of the voltage gated K+ channel Kv1.3 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid inducible kinase SGK1.

PubMed ID: 15040001

DOI: 10.1002/jcp.10430

PubMed ID: 20511718

Title: The serum and glucocorticoid inducible kinases SGK1-3 stimulate the neutral amino acid transporter SLC6A19.

PubMed ID: 20511718

DOI: 10.1159/000315092

PubMed ID: 21865597

Title: Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+ exchanger NHE3 by glucocorticoids.

PubMed ID: 21865597

DOI: 10.1091/mbc.e11-04-0328

PubMed ID: 16460280

Title: Sgk kinases and their role in epithelial transport.

PubMed ID: 16460280

DOI: 10.1146/annurev.physiol.68.040104.131654

PubMed ID: 20919962

Title: Second AKT: the rise of SGK in cancer signalling.

PubMed ID: 20919962

DOI: 10.3109/08977194.2010.518616

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 367
  • Mass: 41175
  • Checksum: E53F1ABE253F648B
  • Sequence:
  • MNSSPAGTPS PQPSRANGNI NLGPSANPNA QPTDFDFLKV IGKGNYGKVL LAKRKSDGAF 
    YAVKVLQKKS ILKKKEQSHI MAERSVLLKN VRHPFLVGLR YSFQTPEKLY FVLDYVNGGE 
    LFFHLQRERR FLEPRARFYA AEVASAIGYL HSLNIIYRDL KPENILLDCQ GHVVLTDFGL 
    CKEGVEPEDT TSTFCGTPEY LAPEVLRKEP YDRAVDWWCL GAVLYEMLHG LPPFYSQDVS 
    QMYENILHQP LQIPGGRTVA ACDLLQSLLH KDQRQRLGSK ADFLEIKNHV FFSPINWDDL 
    YHKRLTPPFN PNVTGPADLK HFDPEFTQEA VSKSIGCTPD TVASSSGASS AFLGFSYAPE 
    DDDILDC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.