Details for: HIPK3

Gene ID: 10114

Symbol: HIPK3

Ensembl ID: ENSG00000110422

Description: homeodomain interacting protein kinase 3

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 3.01
    Marker Score: 67,337
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.46
    Marker Score: 1,466
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 2.38
    Marker Score: 2,966
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 2.33
    Marker Score: 2,486
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 2.31
    Marker Score: 3,359
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.24
    Marker Score: 4,917
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 2.13
    Marker Score: 4,102
  • Cell Name: fat cell (CL0000136)
    Fold Change: 2.06
    Marker Score: 1,150
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.06
    Marker Score: 2,366
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.05
    Marker Score: 598
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2
    Marker Score: 42,663
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1.99
    Marker Score: 1,104
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.94
    Marker Score: 1,722
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.94
    Marker Score: 1,135
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.84
    Marker Score: 62,670
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.76
    Marker Score: 1,675
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.72
    Marker Score: 2,319
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.65
    Marker Score: 6,923
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.6
    Marker Score: 1,686
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.6
    Marker Score: 1,721
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.58
    Marker Score: 6,445
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.58
    Marker Score: 96,981
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 1.58
    Marker Score: 5,416
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.56
    Marker Score: 14,837
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 1.56
    Marker Score: 3,113
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 1.55
    Marker Score: 13,489
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.55
    Marker Score: 58,816
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.55
    Marker Score: 5,504
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.54
    Marker Score: 571
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.54
    Marker Score: 5,946
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 1.53
    Marker Score: 828
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.53
    Marker Score: 11,713
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 1.52
    Marker Score: 366
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.5
    Marker Score: 55,505
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.5
    Marker Score: 24,115
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.5
    Marker Score: 22,451
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.5
    Marker Score: 1,656
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 1.49
    Marker Score: 705
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.48
    Marker Score: 12,746
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.46
    Marker Score: 3,334
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.46
    Marker Score: 769
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.45
    Marker Score: 13,675
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.45
    Marker Score: 3,053
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 1.44
    Marker Score: 1,290
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.44
    Marker Score: 12,619
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 1.42
    Marker Score: 450
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.42
    Marker Score: 14,631
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 1.4
    Marker Score: 1,068
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.39
    Marker Score: 27,600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.39
    Marker Score: 2,141
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.39
    Marker Score: 673
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.38
    Marker Score: 77,394
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.37
    Marker Score: 1,389
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.37
    Marker Score: 1,766
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.37
    Marker Score: 348
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.37
    Marker Score: 465
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.37
    Marker Score: 496
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 1.36
    Marker Score: 620
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.36
    Marker Score: 428
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 1.35
    Marker Score: 3,329
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: 1.35
    Marker Score: 1,216
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 1.35
    Marker Score: 3,352
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.34
    Marker Score: 660
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.33
    Marker Score: 496
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.33
    Marker Score: 1,605
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.32
    Marker Score: 869
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.31
    Marker Score: 493
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.29
    Marker Score: 4,589
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.29
    Marker Score: 297
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.28
    Marker Score: 748
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.28
    Marker Score: 19,990
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.27
    Marker Score: 5,268
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 1.26
    Marker Score: 3,051
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 1.26
    Marker Score: 1,525
  • Cell Name: lung microvascular endothelial cell (CL2000016)
    Fold Change: 1.26
    Marker Score: 268
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.25
    Marker Score: 361
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 1.25
    Marker Score: 484
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.24
    Marker Score: 725
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.24
    Marker Score: 616
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.24
    Marker Score: 1,326
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.24
    Marker Score: 1,137
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 1.22
    Marker Score: 3,086
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.22
    Marker Score: 1,055
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.22
    Marker Score: 4,512
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.21
    Marker Score: 1,720
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.21
    Marker Score: 1,052
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.21
    Marker Score: 5,213
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 1.2
    Marker Score: 440
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 1.2
    Marker Score: 316
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.2
    Marker Score: 921
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.18
    Marker Score: 1,183
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.17
    Marker Score: 7,540
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.17
    Marker Score: 3,128
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 1.16
    Marker Score: 2,258
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.15
    Marker Score: 20,463
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 1.13
    Marker Score: 409
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 1.12
    Marker Score: 554
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 1.12
    Marker Score: 762
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.11
    Marker Score: 1,642
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.11
    Marker Score: 348

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Serine/Threonine Kinase Activity**: HIPK3 possesses intrinsic serine/threonine kinase activity, enabling it to phosphorylate and regulate various substrates. 2. **Apoptosis Regulation**: HIPK3 is involved in the negative regulation of apoptotic processes, suggesting its potential as a pro-survival factor in various cell types. 3. **Transcriptional Regulation**: HIPK3 interacts with transcription factors, such as GATA3, to regulate gene expression and cellular differentiation. 4. **Cellular Localization**: HIPK3 is predominantly localized to the nucleus and cytosol, where it can interact with various signaling pathways and transcriptional regulators. **Pathways and Functions:** 1. **Apoptotic Process**: HIPK3 negatively regulates apoptotic processes by phosphorylating and modulating key pro-apoptotic proteins, such as BAX and BAK. 2. **Protein Kinase Activity**: HIPK3 regulates protein kinase activity by phosphorylating and modulating kinases involved in various signaling pathways. 3. **Transcriptional Regulation**: HIPK3 interacts with transcription factors, such as GATA3, to regulate gene expression and cellular differentiation. 4. **Cell Cycle Regulation**: HIPK3 regulates cell cycle progression by phosphorylating and modulating key cell cycle regulators, such as cyclin-dependent kinases. **Clinical Significance:** 1. **Cardiac Diseases**: HIPK3 has been implicated in cardiac development and disease, including cardiomyopathy and heart failure. Dysregulation of HIPK3 may contribute to cardiac dysfunction and apoptosis. 2. **Cancer**: HIPK3 has been shown to regulate apoptosis and cell cycle progression in various cancer types, including breast, prostate, and lung cancer. HIPK3 may serve as a potential therapeutic target for cancer therapy. 3. **Neurological Disorders**: HIPK3 has been implicated in neurological disorders, including Alzheimer's disease and Parkinson's disease. Dysregulation of HIPK3 may contribute to neurodegeneration and apoptosis. 4. **Endothelial Dysfunction**: HIPK3 regulates endothelial function and vascular tone, suggesting its potential involvement in cardiovascular diseases, such as atherosclerosis and hypertension. In conclusion, HIPK3 is a multifunctional kinase that regulates various cellular processes, including apoptosis, proliferation, and differentiation. Its dysregulation has been implicated in various diseases, including cardiac diseases, cancer, neurological disorders, and endothelial dysfunction. Further research is needed to fully elucidate the role of HIPK3 in human disease and to explore its potential as a therapeutic target.

Genular Protein ID: 4090653176

Symbol: HIPK3_HUMAN

Name: Homeodomain-interacting protein kinase 3

UniProtKB Accession Codes:

Q9H422 O14632 Q2PBG4 Q2PBG5 Q92632 Q9HAS2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CPTAC 2 CTD 1 ChEBI 12 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 DrugCentral 1 EC 3 EMBL 4 EPD 1 Ensembl 4 ExpressionAtlas 1 GO 18 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 2 PRO 1 PROSITE 3 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 6 Rhea 6 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9373137

Title: Identification and sequence of human PKY, a putative kinase with increased expression in multidrug-resistant cells, with homology to yeast protein kinase Yak1.

PubMed ID: 9373137

DOI: 10.1016/s0378-1119(97)00350-8

PubMed ID: 11034606

Title: FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits Fas-mediated Jun NH2-terminal kinase activation.

PubMed ID: 11034606

DOI: 10.1084/jem.192.8.1165

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 9725910

Title: Activation of androgen receptor function by a novel nuclear protein kinase.

PubMed ID: 9725910

DOI: 10.1091/mbc.9.9.2527

PubMed ID: 10961991

Title: Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif.

PubMed ID: 10961991

DOI: 10.1074/jbc.m004293200

PubMed ID: 14766760

Title: JNK regulates HIPK3 expression and promotes resistance to Fas-mediated apoptosis in DU 145 prostate carcinoma cells.

PubMed ID: 14766760

DOI: 10.1074/jbc.m307629200

PubMed ID: 17210646

Title: Cyclic AMP stimulates SF-1-dependent CYP11A1 expression through homeodomain-interacting protein kinase 3-mediated Jun N-terminal kinase and c-Jun phosphorylation.

PubMed ID: 17210646

DOI: 10.1128/mcb.02253-06

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 1215
  • Mass: 133743
  • Checksum: E952D04786955721
  • Sequence:
    • MASQVLVYPP YVYQTQSSAF CSVKKLKVEP SSCVFQERNY PRTYVNGRNF GNSHPPTKGS 
AFQTKIPFNR PRGHNFSLQT SAVVLKNTAG ATKVIAAQAQ QAHVQAPQIG AWRNRLHFLE 
GPQRCGLKRK SEELDNHSSA MQIVDELSIL PAMLQTNMGN PVTVVTATTG SKQNCTTGEG 
DYQLVQHEVL CSMKNTYEVL DFLGRGTFGQ VVKCWKRGTN EIVAIKILKN HPSYARQGQI 
EVSILARLST ENADEYNFVR AYECFQHRNH TCLVFEMLEQ NLYDFLKQNK FSPLPLKVIR 
PILQQVATAL KKLKSLGLIH ADLKPENIML VDPVRQPYRV KVIDFGSASH VSKTVCSTYL 
QSRYYRAPEI ILGLPFCEAI DMWSLGCVIA ELFLGWPLYP GALEYDQIRY ISQTQGLPGE 
QLLNVGTKST RFFCKETDMS HSGWRLKTLE EHEAETGMKS KEARKYIFNS LDDVAHVNTV 
MDLEGSDLLA EKADRREFVS LLKKMLLIDA DLRITPAETL NHPFVNMKHL LDFPHSNHVK 
SCFHIMDICK SHLNSCDTNN HNKTSLLRPV ASSSTATLTA NFTKIGTLRS QALTTSAHSV 
VHHGIPLQAG TAQFGCGDAF QQTLIICPPA IQGIPATHGK PTSYSIRVDN TVPLVTQAPA 
VQPLQIRPGV LSQTWSGRTQ QMLVPAWQQV TPLAPATTTL TSESVAGSHR LGDWGKMISC 
SNHYNSVMPQ PLLTNQITLS APQPVSVGIA HVVWPQPATT KKNKQCQNRG ILVKLMEWEP 
GREEINAFSW SNSLQNTNIP HSAFISPKII NGKDVEEVSC IETQDNQNSE GEARNCCETS 
IRQDSDSSVS DKQRQTIIIA DSPSPAVSVI TISSDTDEEE TSQRHSLREC KGSLDCEACQ 
STLNIDRMCS LSSPDSTLST SSSGQSSPSP CKRPNSMSDE EQESSCDTVD GSPTSDSSGH 
DSPFAESTFV EDTHENTELV SSADTETKPA VCSVVVPPVE LENGLNADEH MANTDSICQP 
LIKGRSAPGR LNQPSAVGTR QQKLTSAFQQ QHLNFSQVQH FGSGHQEWNG NFGHRRQQAY 
IPTSVTSNPF TLSHGSPNHT AVHAHLAGNT HLGGQPTLLP YPSSATLSSA APVAHLLASP 
CTSRPMLQHP TYNISHPSGI VHQVPVGLNP RLLPSPTIHQ TQYKPIFPPH SYIAASPAYT 
GFPLSPTKLS QYPYM

Genular Protein ID: 3533882124

Symbol: A8KAE4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8KAE4

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 1 DNASU 1 EMBL 2 GO 2 Gene3D 1 GenomeRNAi 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 1194
  • Mass: 131304
  • Checksum: 57950AF47864C936
  • Sequence:
    • MASQVLVYPP YVYQTQSSAF CSVKKLKVEP SSCVFQERNY PRTYVNGRNF GNSHPPTKGS 
AFQTKIPFNR PRGHNFSLQT SAVVLKNTAG ATKVIAAQAQ QAHVQAPQIG AWRNRLHFLE 
GPQRCGLKRK SEELDNHSSA MQIVDELSIL PAMLQTNMGN PVTVVTATTG SKQNCTTGEG 
DYQLVQHEVL CSMKNTYEVL DFLGRGTFGQ VVKCWKRGTN EIVAIKILKN HPSYARQGQI 
EVSILARLST ENADEYNFVR AYECFQHRNH TCLVFEMLEQ NLYDFLKQNK FSPLPLKVIR 
PILQQVATAL KKLKSLGLIH ADLKPENIML VDPVRQPYRV KVIDFGSASH VSKTVCSTYL 
QSRYYRAPEI ILGLPFCEAI DMWSLGCVIA ELFLGWPLYP GALEYDQIRY ISQTQGLPGE 
QLLNVGTKST RFFCKETDMS HSGWRLKTLE EHEAETGMKS KEARKYIFNS LDDVAHVNTV 
MDLEGSDLLA EKADRREFVS LLKKMLLIDA DLRITPAETL NHPFVNMKHL LDFPHSNHVK 
SCFHIMDICK SHLNSCDTNN HNKTSLLRPV ASSSTATLTA NFTKIGTLRS QALTTSAHSV 
VHHGIPLQAG TAQFGCGDAF QQTSIICPPA IQGIPATHGK PTSYSIRVYN TVPLVTQAPA 
VQPLQIRPGV LSQTWSGRTQ QMLVPAWQQV TPLAPATTTL TSESVAGSHR LGDWGKMISC 
SNHYNSVMPQ PLLTNQITLS APQPVSVGIA YVVWPQPATT KKNKQCQNRS NSLQNTNIPH 
SAFISPKIIN GKDVEEVSCI ETQDNQNSEG EARNCCETSI RQDSDSSVSD KQRQTIIIAD 
SPSPAVSVIT ISSDTDEEET SQRHSLRECK GSLDCEACQS TLNIDRMCSL SSPDSTLSTS 
SSGQSSPSPC KRPNSMSDEE QESSCDTVDG SPTSDSSGHD SPFAESTFVE DTHENTELVS 
SADTETKPAV CSVVVPPVEL ENGLNADEHM ANTDSICQPL IKGRSAPGRL NQPSAVGTRQ 
QKLTSAFQQQ HLNFSQVQHF GSGHQEWNGN FGHRRQQAYI PTSVTSNPFT LSHGSPNHTA 
VHAHLAGNTH LGGQPTLLPY PSSATLSSAA PVAHLLASPC TSRPMLQHPT YNISHPSGIV 
HQVPVGLNPR LLPSPTIHQT QYKPIFPPHS YIAASPAYTG FPLSPTKLSQ YPYM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.