Details for: FEM1B
Associated with
Other Information
Genular Protein ID: 424890564
Symbol: FEM1B_HUMAN
Name: FEM1-beta
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10542291
Title: F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis.
PubMed ID: 10542291
PubMed ID: 10623617
Title: Sequence, organization, and expression of the human FEM1B gene.
PubMed ID: 10623617
PubMed ID: 9455477
Title: Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 9455477
PubMed ID: 12168954
Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
PubMed ID: 12168954
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11559703
Title: The Caenorhabditis elegans sex-determining protein fem-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis.
PubMed ID: 11559703
PubMed ID: 15601820
Title: VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.
PubMed ID: 15601820
DOI: 10.1101/gad.1252404
PubMed ID: 19330022
Title: Human FEM1B is required for Rad9 recruitment and CHK1 activation in response to replication stress.
PubMed ID: 19330022
DOI: 10.1038/onc.2009.58
PubMed ID: 24076122
Title: Fem1b promotes ubiquitylation and suppresses transcriptional activity of Gli1.
PubMed ID: 24076122
PubMed ID: 28118078
Title: FEM1 proteins are ancient regulators of SLBP degradation.
PubMed ID: 28118078
PubMed ID: 29779948
Title: The eukaryotic proteome is shaped by E3 ubiquitin ligases targeting C-terminal degrons.
PubMed ID: 29779948
PubMed ID: 33398170
Title: Molecular basis for ubiquitin ligase CRL2FEM1C-mediated recognition of C-degron.
PubMed ID: 33398170
PubMed ID: 33398168
Title: Molecular basis for arginine C-terminal degron recognition by Cul2FEM1 E3 ligase.
PubMed ID: 33398168
Sequence Information:
- Length: 627
- Mass: 70264
- Checksum: 85DA943663A988C1
- Sequence:
MEGLAGYVYK AASEGKVLTL AALLLNRSES DIRYLLGYVS QQGGQRSTPL IIAARNGHAK VVRLLLEHYR VQTQQTGTVR FDGYVIDGAT ALWCAAGAGH FEVVKLLVSH GANVNHTTVT NSTPLRAACF DGRLDIVKYL VENNANISIA NKYDNTCLMI AAYKGHTDVV RYLLEQRADP NAKAHCGATA LHFAAEAGHI DIVKELIKWR AAIVVNGHGM TPLKVAAESC KADVVELLLS HADCDRRSRI EALELLGASF ANDRENYDII KTYHYLYLAM LERFQDGDNI LEKEVLPPIH AYGNRTECRN PQELESIRQD RDALHMEGLI VRERILGADN IDVSHPIIYR GAVYADNMEF EQCIKLWLHA LHLRQKGNRN THKDLLRFAQ VFSQMIHLNE TVKAPDIECV LRCSVLEIEQ SMNRVKNISD ADVHNAMDNY ECNLYTFLYL VCISTKTQCS EEDQCKINKQ IYNLIHLDPR TREGFTLLHL AVNSNTPVDD FHTNDVCSFP NALVTKLLLD CGAEVNAVDN EGNSALHIIV QYNRPISDFL TLHSIIISLV EAGAHTDMTN KQNKTPLDKS TTGVSEILLK TQMKMSLKCL AARAVRANDI NYQDQIPRTL EEFVGFH
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.