Details for: RASGRP1

Gene ID: 10125

Symbol: RASGRP1

Ensembl ID: ENSG00000172575

Description: RAS guanyl releasing protein 1

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.66
    Marker Score: 14,273
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.62
    Marker Score: 15,416
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.57
    Marker Score: 2,222
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 1.53
    Marker Score: 4,297
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 1.48
    Marker Score: 1,381
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 168,439
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.46
    Marker Score: 4,179
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.45
    Marker Score: 2,233
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.4
    Marker Score: 8,969
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.4
    Marker Score: 20,924
  • Cell Name: memory regulatory T cell (CL0002678)
    Fold Change: 1.35
    Marker Score: 470
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 1.3
    Marker Score: 12,836
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 1.28
    Marker Score: 637
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 1.27
    Marker Score: 393
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.26
    Marker Score: 543
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.25
    Marker Score: 753
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.25
    Marker Score: 11,756
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.23
    Marker Score: 2,894
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 1.22
    Marker Score: 1,321
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.2
    Marker Score: 2,278
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 1.2
    Marker Score: 724
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.19
    Marker Score: 867
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.19
    Marker Score: 72,956
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 1.15
    Marker Score: 968
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.13
    Marker Score: 4,755
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.12
    Marker Score: 864
  • Cell Name: interneuron (CL0000099)
    Fold Change: 1.07
    Marker Score: 487
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: 1.07
    Marker Score: 625
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 1.06
    Marker Score: 537
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 1.05
    Marker Score: 2,913
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 1.05
    Marker Score: 3,318
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 1.03
    Marker Score: 54,358
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 1.03
    Marker Score: 590
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,754
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,978
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 0.98
    Marker Score: 1,759
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,403
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.97
    Marker Score: 658
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.95
    Marker Score: 490
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,407
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 0.95
    Marker Score: 335
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.94
    Marker Score: 446
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.93
    Marker Score: 386
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.92
    Marker Score: 290
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,723
  • Cell Name: naive T cell (CL0000898)
    Fold Change: 0.91
    Marker Score: 585
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.9
    Marker Score: 361
  • Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
    Fold Change: 0.88
    Marker Score: 641
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.88
    Marker Score: 316
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.87
    Marker Score: 4,981
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,259
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.86
    Marker Score: 13,487
  • Cell Name: natural T-regulatory cell (CL0000903)
    Fold Change: 0.86
    Marker Score: 441
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.85
    Marker Score: 888
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: 0.85
    Marker Score: 257
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 0.84
    Marker Score: 1,164
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 0.83
    Marker Score: 347
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.8
    Marker Score: 614
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 0.8
    Marker Score: 608
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: 0.8
    Marker Score: 1,372
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 0.79
    Marker Score: 1,993
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.78
    Marker Score: 843
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.78
    Marker Score: 227
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.76
    Marker Score: 1,237
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.76
    Marker Score: 442
  • Cell Name: intraepithelial lymphocyte (CL0002496)
    Fold Change: 0.75
    Marker Score: 838
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.74
    Marker Score: 383
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.73
    Marker Score: 1,225
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.72
    Marker Score: 656
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 0.7
    Marker Score: 222
  • Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
    Fold Change: 0.69
    Marker Score: 156
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.68
    Marker Score: 775
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.68
    Marker Score: 174
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.68
    Marker Score: 1,375
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 0.67
    Marker Score: 585
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.66
    Marker Score: 482
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 0.66
    Marker Score: 935
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.65
    Marker Score: 3,886
  • Cell Name: CD56-positive, CD161-positive immature natural killer cell, human (CL0002338)
    Fold Change: 0.64
    Marker Score: 212
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.64
    Marker Score: 2,480
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 0.64
    Marker Score: 175
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 0.64
    Marker Score: 1,558
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: 0.64
    Marker Score: 351
  • Cell Name: CD4-positive, CD25-positive, alpha-beta regulatory T cell (CL0000792)
    Fold Change: 0.63
    Marker Score: 167
  • Cell Name: activated CD4-positive, alpha-beta T cell, human (CL0001043)
    Fold Change: 0.62
    Marker Score: 284
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.62
    Marker Score: 746
  • Cell Name: regulatory T cell (CL0000815)
    Fold Change: 0.61
    Marker Score: 679
  • Cell Name: intermediate monocyte (CL0002393)
    Fold Change: 0.61
    Marker Score: 212
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.61
    Marker Score: 6,155
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 0.61
    Marker Score: 2,600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.59
    Marker Score: 270
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 0.59
    Marker Score: 638
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: 0.59
    Marker Score: 953
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 0.59
    Marker Score: 429
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: 0.58
    Marker Score: 1,314
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 0.58
    Marker Score: 490
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 0.57
    Marker Score: 561
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 0.56
    Marker Score: 773
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.56
    Marker Score: 356
  • Cell Name: memory T cell (CL0000813)
    Fold Change: 0.56
    Marker Score: 239

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RASGRP1 is a guanyl-releasing protein that binds to the small GTPase RAS, facilitating the exchange of GDP for GTP. This exchange enables RAS to activate downstream signaling pathways involved in cell proliferation, differentiation, and survival. RASGRP1 is also involved in the regulation of calcium ion binding, diacylglycerol binding, and phosphatidylcholine binding, which are essential for various cellular processes. **Pathways and Functions:** RASGRP1 is involved in multiple signaling pathways, including: 1. **Activation of GTPase activity**: RASGRP1 facilitates the exchange of GDP for GTP in RAS, enabling the activation of downstream signaling pathways. 2. **Activation of Ras in B cells**: RASGRP1 is required for the activation of Ras in B cells, which is essential for B cell proliferation and differentiation. 3. **Adaptive immune system**: RASGRP1 plays a crucial role in the regulation of immune cell activation and proliferation in the adaptive immune system. 4. **B cell activation**: RASGRP1 is involved in the regulation of B cell activation and proliferation. 5. **Calcium ion binding**: RASGRP1 binds to calcium ions, which is essential for various cellular processes, including cell signaling and differentiation. 6. **G alpha (q) signaling events**: RASGRP1 is involved in the regulation of G alpha (q) signaling events, which are essential for cell proliferation and differentiation. **Clinical Significance:** RASGRP1's involvement in immune cell signaling pathways makes it a potential target for therapeutic interventions in immune-related disorders, such as: 1. **Autoimmune diseases**: RASGRP1's role in B cell activation and proliferation makes it a potential target for the treatment of autoimmune diseases, such as rheumatoid arthritis and lupus. 2. **Cancer**: RASGRP1's involvement in cell proliferation and differentiation makes it a potential target for the treatment of various cancers, including leukemia and lymphoma. 3. **Infectious diseases**: RASGRP1's role in immune cell signaling pathways makes it a potential target for the treatment of infectious diseases, such as HIV and tuberculosis. In conclusion, RASGRP1 is a multifaceted gene involved in various cellular signaling pathways, including immune cell signaling. Its involvement in immune cell activation, proliferation, and differentiation makes it a potential target for therapeutic interventions in immune-related disorders.

Genular Protein ID: 3520043057

Symbol: GRP1_HUMAN

Name: RAS guanyl-releasing protein 1

UniProtKB Accession Codes:

O95267 Q56CZ0 Q58G75 Q59HB1 Q5I3A8 Q6GV31 Q6NX39 Q7LDG6 Q9UI94 Q9UNN9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 4 CORUM 1 CTD 1 ChEBI 5 ChEMBL 1 DNASU 1 DisGeNET 1 EMBL 11 Ensembl 5 ExpressionAtlas 1 GO 40 Gene3D 5 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 2 PRINTS 1 PRO 1 PROSITE 6 PROSITE-ProRule 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 RNAct 1 Reactome 6 RefSeq 3 SAM 1 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 9789079

Title: A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia.

PubMed ID: 9789079

DOI: 10.1073/pnas.95.22.13278

PubMed ID: 10087292

Title: RasGRP, a Ras activator: mouse and human cDNA sequences and chromosomal positions.

PubMed ID: 10087292

DOI: 10.1007/s003359901001

PubMed ID: 17878389

Title: Defective expression of ras guanyl nucleotide-releasing protein 1 in a subset of patients with systemic lupus erythematosus.

PubMed ID: 17878389

DOI: 10.4049/jimmunol.179.7.4890

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10807788

Title: RasGRP links T-cell receptor signaling to Ras.

PubMed ID: 10807788

PubMed ID: 11257115

Title: Diacylglycerol kinase zeta regulates Ras activation by a novel mechanism.

PubMed ID: 11257115

DOI: 10.1083/jcb.152.6.1135

PubMed ID: 11919165

Title: Expression of a catalytically inactive form of diacylglycerol kinase alpha induces sustained signaling through RasGRP.

PubMed ID: 11919165

DOI: 10.1096/fj.01-0762fje

PubMed ID: 12839994

Title: Vav mediates Ras stimulation by direct activation of the GDP/GTP exchange factor Ras GRP1.

PubMed ID: 12839994

DOI: 10.1093/emboj/cdg316

PubMed ID: 12782630

Title: Exchange factors of the RasGRP family mediate Ras activation in the Golgi.

PubMed ID: 12782630

DOI: 10.1074/jbc.m302807200

PubMed ID: 12845332

Title: Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1.

PubMed ID: 12845332

DOI: 10.1038/nature01806

PubMed ID: 15060167

Title: Ras activation in Jurkat T cells following low-grade stimulation of the T-cell receptor is specific to N-Ras and occurs only on the Golgi apparatus.

PubMed ID: 15060167

DOI: 10.1128/mcb.24.8.3485-3496.2004

PubMed ID: 15184873

Title: Inverted signaling hierarchy between RAS and RAC in T-lymphocytes.

PubMed ID: 15184873

DOI: 10.1038/sj.onc.1207768

PubMed ID: 15657177

Title: Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells.

PubMed ID: 15657177

DOI: 10.1182/blood-2004-10-3916

PubMed ID: 15899849

Title: A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells.

PubMed ID: 15899849

DOI: 10.1128/mcb.25.11.4426-4441.2005

PubMed ID: 17658605

Title: SKAP55 modulates T cell antigen receptor-induced activation of the Ras-Erk-AP1 pathway by binding RasGRP1.

PubMed ID: 17658605

DOI: 10.1016/j.molimm.2007.05.024

PubMed ID: 19933860

Title: RasGRP1 is required for human NK cell function.

PubMed ID: 19933860

DOI: 10.4049/jimmunol.0902012

PubMed ID: 27776107

Title: RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics.

PubMed ID: 27776107

DOI: 10.1038/ni.3575

PubMed ID: 23908768

Title: Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1.

PubMed ID: 23908768

DOI: 10.7554/elife.00813

PubMed ID: 28822832

Title: Combined immunodeficiency with EBV positive B cell lymphoma and epidermodysplasia verruciformis due to a novel homozygous mutation in RASGRP1.

PubMed ID: 28822832

DOI: 10.1016/j.clim.2017.08.007

PubMed ID: 29155103

Title: RASGRP1 mutation in autoimmune lymphoproliferative syndrome-like disease.

PubMed ID: 29155103

DOI: 10.1016/j.jaci.2017.10.026

Sequence Information:

  • Length: 797
  • Mass: 90402
  • Checksum: 8ACDCF0F715ABAA9
  • Sequence:
    • MGTLGKAREA PRKPSHGCRA ASKARLEAKP ANSPFPSHPS LAHITQFRMM VSLGHLAKGA 
SLDDLIDSCI QSFDADGNLC RSNQLLQVML TMHRIVISSA ELLQKVITLY KDALAKNSPG 
LCLKICYFVR YWITEFWVMF KMDASLTDTM EEFQELVKAK GEELHCRLID TTQINARDWS 
RKLTQRIKSN TSKKRKVSLL FDHLEPEELS EHLTYLEFKS FRRISFSDYQ NYLVNSCVKE 
NPTMERSIAL CNGISQWVQL MVLSRPTPQL RAEVFIKFIQ VAQKLHQLQN FNTLMAVIGG 
LCHSSISRLK ETSSHVPHEI NKVLGEMTEL LSSSRNYDNY RRAYGECTDF KIPILGVHLK 
DLISLYEAMP DYLEDGKVNV HKLLALYNHI SELVQLQEVA PPLEANKDLV HLLTLSLDLY 
YTEDEIYELS YAREPRNHRA PPLTPSKPPV VVDWASGVSP KPDPKTISKH VQRMVDSVFK 
NYDHDQDGYI SQEEFEKIAA SFPFSFCVMD KDREGLISRD EITAYFMRAS SIYSKLGLGF 
PHNFQETTYL KPTFCDNCAG FLWGVIKQGY RCKDCGMNCH KQCKDLVVFE CKKRAKNPVA 
PTENNTSVGP VSNLCSLGAK DLLHAPEEGP FTFPNGEAVE HGEESKDRTI MLMGVSSQKI 
SLRLKRAVAH KATQTESQPW IGSEGPSGPF VLSSPRKTAQ DTLYVLPSPT SPCPSPVLVR 
KRAFVKWENK DSLIKSKEEL RHLRLPTYQE LEQEINTLKA DNDALKIQLK YAQKKIESLQ 
LEKSNHVLAQ MEQGDCS

Genular Protein ID: 3974905832

Symbol: B2RA89_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2RA89

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 4 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 5 Genevisible 1 GenomeRNAi 1 InterPro 11 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 10 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 2 SAM 2 SMART 4 SUPFAM 3

Sequence Information:

  • Length: 797
  • Mass: 90403
  • Checksum: 5C16AFD979F0920B
  • Sequence:
    • MGTLGKAREA PRKPSHGCRA ASKARLEAKP ANSPFPSHPS LAHITQFRMM VSLGHLAKGA 
SLDDLIDSCI QSFDADGNLC RSNQLLQVML TMHRIVISSA ELLQKVITLY KDALAKNSPG 
LCLKICYFVR YWITEFWVMF KMDASLTDTM EEFQELVKAK GEELHCRLID TTQINARDWS 
RKLTQRIKSN TSKKRKVSLL FDHLEPEELS EHLTYLEFKS FRRISFSDYQ NYLVNSCVKE 
NPTMERSIAL CNGISQWVQL MVLSRPTPQL RAEVFIKFIQ VAQKLHQLQN FNTLMAVIGG 
LCHSSISRLK ETSSHVPHEI NKVLGEMTEL LSSSRNYDNY RRAYGECTDF KIPILGVHLK 
DLISLYEAMP DYLEDGKVNV HKLLALYNHI SELVQLQEVA PPLEANKDLV HLLTLSLDLY 
YTEDEIYELS YAREPRNHRA PPLTPSKPPV VVDWASGVSP KPDPKTISKH VQRMVDSVFK 
NYDHDQDGYI SQEEFEKIAA SFPFSFCVMD KDREGLISRD EITAYFMRAS SIYSKLGLGF 
PHNFQETTYL KPTFCDNCAG FLWGVIKQGY RCKDCGMNCH KQCKDLVVFE CKKRAKNPVA 
PTENNTSVGP VSNLCSLGAK DLLHAPEEGP FTFPNGEAVE HGEESKDRTI MLMGVSSQKI 
SLRLKRAVAH KATQTESQPW IGSEGPSGPF VLSSPRETAQ DTLYVLPSPT SPCPSPVLVR 
KRAFVKWENK DSLIKSKEEL RHLRLPTYQE LEQEINTLKA DNDALKIQLK YAQKKIESLQ 
LEKSNHVLAQ MEQGDCS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.